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T-REX of RBC Genetic Variants to Prevent or Ameliorate Cerebral Malaria

April 19, 2018 - 05:57 -- Philip JAJOSKY
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As of April 2018, there are 4 PubMed articles that propose the immediate evaluation of T-REX for the prevention of malaria deaths (under author name "JAJOSKY"). These proposals represent 4 (malaria-specific) cell-therapy variations of the special-donor concept highlighted by the successful (HIV-specific) cell-therapy administered to "the Berlin patient."

Not Open Access | Intravenous Artesunate for the Treatment of Severe and Complicated Malaria in the United States: Clinical Use Under an Investigational New Drug Protocol

October 7, 2015 - 14:14 -- NOT Open Access
Author(s): 
Patrick S. Twomey, Bryan L. Smith, Cathy McDermott, Anne Novitt-Moreno, William McCarthy, S. Patrick Kachur and Paul M. Arguin
Reference: 
Ann Intern Med. 2015;163(7):498-506.

To assess the safety and clinical benefit of intravenous artesunate as an alternative to quinidine.

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Open Access | Malaria Surveillance — United States, 2010

March 2, 2012 - 14:17 -- Patrick Sampao
Author(s): 
Sonja Mali, S. Patrick Kachur, Paul M. Arguin
Reference: 
Morbidity and Mortality Weekly Report (MMWR), Volume 61, No. SS-2 March 2, 2012

MalariaWorldThis report summarizes cases in persons with onset of illness in 2010 and summarizes trends during previous years.

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Malaria in the United States – Past and Present

December 21, 2011 - 12:49 -- Patrick Sampao
Author(s): 
Andrea J. Linscott
Reference: 
Clinical Microbiology Newsletter, Volume 33, Issue 7, 1 April 2011, Pages 49-52

MalariaWorldThis article reviews the history of malaria and its eradication in the U.S. and discusses methods for laboratory diagnosis.

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Open Access | State of malaria diagnostic testing at clinical laboratories in the United States, 2010: a nationwide survey

November 15, 2011 - 07:17 -- Kabogo Ndegwa
Author(s): 
Abanyie FA, Arguin PM, Gutman J
Reference: 
Malaria Journal 2011, 10:340 (10 November 2011)

MalariaWorldAlthough malaria diagnostic testing services were available to a majority of U.S. laboratories surveyed, very few were in complete compliance with all of the CLSI guidelines for analysis and reporting of results, and most respondents reported very few cases of malaria annually.

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Presumptive Treatment to Reduce Imported Malaria among Refugees from East Africa Resettling in the United States

October 10, 2011 - 08:03 -- Patrick Sampao
Author(s): 
Christina R. Phares, Bryan K. Kapella, Annelise C. Doney, Paul M. Arguin, Michael Green, Leul Mekonnen, Aleksander Galev, Michelle Weinberg, and William M. Stauffer
Reference: 
Am J Trop Med Hyg 2011 85:612-615

Refugees from East Africa Resettling in the United StatesDuring May 4, 2007–February 29, 2008, the United States resettled 6,159 refugees from Tanzania. Refugees received pre-departure antimalarial treatment with sulfadoxine-pyrimethamine (SP), partially supervised (three/six doses) artemether-lumefantrine (AL), or fully supervised AL.

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A Local, Regional, and National Assessment of Pediatric Malaria in the United States

May 10, 2011 - 07:20 -- Kabogo Ndegwa
Author(s): 
Patrick W. Hickey, Kathryn E. Cape, Penny Masuoka, Joseph M. Campos, William Pastor, Edward C. Wong and Nalini Singh
Reference: 
Journal of Travel Medicine, Volume 18, Issue 3, pages 153–160, May/June 2011

Malaria is a preventable disease for which the risk to life and costs of treatment are significant.

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Open Access | Malaria Surveillance --- United States, 2009

April 28, 2011 - 07:00 -- Kabogo Ndegwa
Author(s): 
Sonja Mali, Kathrine R. Tan, Paul M. Arguin
Reference: 
Morbidity and Mortality Weekly Report (MMWR), April 22, 2011 / Vol. 60 / No. SS–3

Decreasing the number of malaria cases in subsequent years will require conveying the importance of adhering to appropriate preventive measures for malaria specifically targeting travelers visiting friends and relatives, missionary, and pregnant populations.

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Comparing the Understanding of Subjects Receiving a Candidate Malaria Vaccine in the United States and Mali

October 4, 2010 - 12:15 -- Patrick Sampao
Author(s): 
Ruth D., Issaka S., et al.
Reference: 
Am J Trop Med Hyg, Oct 2010; 83: 868 - 872.

Initial responses to questionnaires used to assess participants' understanding of informed consent for malaria vaccine trials conducted in the United States and Mali were tallied.

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Open Access | Malaria surveillance --- United States, 2008

July 1, 2010 - 09:18 -- Kabogo Ndegwa
Author(s): 
S Mali, S Steele, L Slutsker, PM Arguin
Reference: 
MMWR Surveill Summ June 25, 2010 / 59(SS07);1-15

CDC received reports of 1,298 cases of malaria with an onset of symptoms in 2008 among patients in the United States, a decrease of 13.8% from the 1,505 cases reported for 2007 (p<0.001). These cases included one transfusion-related case, one congenital case, and two fatal cases. Plasmodium falciparum, P. vivax, P. malariae, and P. ovale were identified in 40.6%, 14.6%, 1.5%, and 1.4% of cases, respectively.

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