HIV-infected individuals on antiretroviral therapy (ART) require treatment with artemisinin-based combination therapy (ACT) when infected with malaria. Artemether–lumefantrine (AL) is the most commonly used ACT for treatment of falciparum malaria in Africa but there is limited evidence on the safety and efficacy of AL in HIV-infected individuals on ART, among whom drug–drug interactions are expected. Day-42 adequate clinical and parasitological response (ACPR) and incidence of adverse events was assessed in HIV-infected individuals on efavirenz-based ART with uncomplicated falciparum malaria treated with AL.
From the sub-set of survey data analysed, non-falciparum species are present and occurred as mixed infections.
The increases in interventions, such as ITNs and IRS, were shown to have contributed to malaria reduction in 2015; however, changes in demographics such as increases in the proportion of more at risk groups among under-five children and rural residents may have overridden the impact of these interventions and resulted in an overall increase.
Routine data are important for researchers and policy makers alike.
The external quality assurance scheme provided periodic representations of clinical and laboratory staff performance.
This study demonstrated that deployment of as few as four CRDs within a hut was associated with reduced indoor mosquito densities.
Human mobility has influenced malaria transmission in Lusaka district through a number of factors by importing infections.
Endogenous α-HRP2 antibodies form immune complexes with HRP2 in the symptomatic patient population of a low-transmission area in rural Southern Zambia.
Free mass distribution of LLINs policy was adopted in 2005 in Zambia.
Co-treating WSEBs with both PM and BA results in wash-resistant insecticidal activity comparable with LLINs.