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Zambia

Efficacy and safety of artemether–lumefantrine as treatment for Plasmodium falciparum uncomplicated malaria in adult patients on efavirenz-based antiretroviral therapy in Zambia: an open label non-randomized interventional trial

May 28, 2019 - 11:31 -- Open Access
Author(s): 
Clifford G. Banda, Mike Chaponda, Victor Mwapasa, et al.
Reference: 
Malaria Journal 2019 18:180, 24 May 2019

HIV-infected individuals on antiretroviral therapy (ART) require treatment with artemisinin-based combination therapy (ACT) when infected with malaria. Artemether–lumefantrine (AL) is the most commonly used ACT for treatment of falciparum malaria in Africa but there is limited evidence on the safety and efficacy of AL in HIV-infected individuals on ART, among whom drug–drug interactions are expected. Day-42 adequate clinical and parasitological response (ACPR) and incidence of adverse events was assessed in HIV-infected individuals on efavirenz-based ART with uncomplicated falciparum malaria treated with AL.

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Distribution of Plasmodium species and assessment of performance of diagnostic tools used during a malaria survey in Southern and Western Provinces of Zambia

April 14, 2019 - 17:03 -- Open Access
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Author(s): 
Lungowe Sitali, John M. Miller, Mulenga C. Mwenda, Daniel J. Bridges, Moonga B. Hawela, Busiku Hamainza, Elizabeth Chizema-Kawesha, Thomas P. Eisele, James Chipeta and Bernt Lindtjørn
Reference: 
Malaria Journal 2019 18:130, 11 April 2019

From the sub-set of survey data analysed, non-falciparum species are present and occurred as mixed infections.

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Investigating the upsurge of malaria prevalence in Zambia between 2010 and 2015: a decomposition of determinants

March 12, 2019 - 15:32 -- Open Access
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Author(s): 
Mukumbuta Nawa, Peter Hangoma, Andrew P. Morse and Charles Michelo
Reference: 
Malaria Journal 2019 18:61, 7 March 2019

The increases in interventions, such as ITNs and IRS, were shown to have contributed to malaria reduction in 2015; however, changes in demographics such as increases in the proportion of more at risk groups among under-five children and rural residents may have overridden the impact of these interventions and resulted in an overall increase.

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A new approach to gathering pharmaceutical market data to support policy implementation and access to medicines: as demonstrated by malaria medicines in Zambia

December 4, 2018 - 14:49 -- Open Access
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Author(s): 
Renia Coghlan, Peter Stephens, Bernice Mwale and Makomani Siyanga
Reference: 
Malaria Journal 2018 17:444, 29 November 2018

Routine data are important for researchers and policy makers alike.

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Outreach training and supportive supervision for malaria case management in Zambia: the effects of focused capacity building on indicators of diagnostic and clinical performance

December 4, 2018 - 14:34 -- Open Access
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Author(s): 
Matt Worges, Nicole Whitehurst, Emanuel Yamo, Hawela Moonga, Joshua Yukich and Luis Benavente
Reference: 
Malaria Journal 2018 17:438, 28 November 2018

The external quality assurance scheme provided periodic representations of clinical and laboratory staff performance.

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Controlled release spatial repellent devices (CRDs) as novel tools against malaria transmission: a semi-field study in Macha, Zambia

November 27, 2018 - 15:34 -- Open Access
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Author(s): 
Jennifer C. Stevenson, Limonty Simubali, Noel M. Elman, et al.
Reference: 
Malaria Journal 2018 17:437, 26 November 2018

This study demonstrated that deployment of as few as four CRDs within a hut was associated with reduced indoor mosquito densities.

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Human mobility and factors associated with malaria importation in Lusaka district, Zambia: a descriptive cross sectional study

November 6, 2018 - 14:09 -- Open Access
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Author(s): 
Miriam Lowa, Lungowe Sitali, Mwiche Siame and Patrick Musonda
Reference: 
Malaria Journal 2018 17:404, 3 November 2018

Human mobility has influenced malaria transmission in Lusaka district through a number of factors by importing infections.

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Evidence for histidine-rich protein 2 immune complex formation in symptomatic patients in Southern Zambia

July 14, 2018 - 15:17 -- Open Access
Author(s): 
Christine F. Markwalter, Lwiindi Mudenda, Mindy Leelawong, Danielle W. Kimmel, Armin Nourani, Saidon Mbambara, Philip E. Thuma and David W. Wright
Reference: 
Malaria Journal 2018 17:256, 9 July 2018

Endogenous α-HRP2 antibodies form immune complexes with HRP2 in the symptomatic patient population of a low-transmission area in rural Southern Zambia.

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Insecticide-treated nets mass distribution campaign: benefits and lessons in Zambia

April 25, 2018 - 15:01 -- Open Access
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Author(s): 
Freddie Masaninga, Nawa Mukumbuta, Elizabeth Kawesha-Chizema, et al.
Reference: 
Malaria Journal 2018 17:173, 24 April 2018

Free mass distribution of LLINs policy was adopted in 2005 in Zambia.

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Wash-resistance of pirimiphos-methyl insecticide treatments of window screens and eave baffles for killing indoor-feeding malaria vector mosquitoes: an experimental hut trial, South East of Zambia

April 17, 2018 - 15:55 -- Open Access
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Author(s): 
Dingani Chinula, Chadwick H. Sikaala, Gerry Killeen, et al.
Reference: 
Malaria Journal 2018 17:164, 13 April 2018

Co-treating WSEBs with both PM and BA results in wash-resistant insecticidal activity comparable with LLINs.

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