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Open Access | Feasibility and acceptability of ACT for the community case management of malaria in urban settings in five African sites

August 19, 2011 - 09:13 -- Patrick Sampao
Author(s): 
Akweongo P, Agyei-Baffour P, Sudhakar M, Simwaka BN, Konate AT, Adongo PB, Browne EN, Tegegn A, Ali D, Traore A, Amuyunzu-Nyamongo M, Pagnoni F, Barnish G
Reference: 
Malaria Journal 2011, 10:240 (16 August 2011)

In all sites, interviews revealed that caregivers' knowledge of malaria signs and symptoms improved after the intervention. Preference for CMDs as providers for malaria increased in all sites.

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Open Access | Insecticidal activity of the essential oil from fruits and seeds of Schinus terebinthifolia Raddi against African malaria vectors

July 7, 2011 - 11:53 -- Patrick Sampao
Author(s): 
Eliningaya J Kweka, Mramba Nyindo, Franklin Mosha and Ary G Silva
Reference: 
Parasites & Vectors 2011, 4:129, 5 July 2011

Twenty third instar larvae of both Anopheles gambiae s.s. and Cx. quinquefasciatus were exposed to different dosages of plant extract in both laboratory and semi- field environments. Observation of the mortality response was assessed at intervals of 12, 24, 48 and 72 hours.

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Open Access | Producing A Successful Malaria Vaccine: Innovation In The Lab And Beyond

June 14, 2011 - 14:20 -- Patrick Sampao
Author(s): 
Christian Loucq, Ashley Birkett, David Poland, Carla Botting, Julia Nunes and Sally Ethelston
Reference: 
Health Aff June 2011 vol. 30 no. 6 1065-1072

This article recounts the pivotal roles in that achievement played by collaborations of nonprofit organizations, pharmaceutical companies, private and public donors, and countries whose citizens would benefit most directly from a vaccine.

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Open Access | Evaluation of a PfHRP2 and a pLDH-based Rapid Diagnostic Test for the Diagnosis of Severe Malaria in 2 Populations of African Children

April 6, 2011 - 12:21 -- Patrick Sampao
Author(s): 
Ilse C. E. Hendriksen, George Mtove, Arjen M. Dondorp, et al
Reference: 
Clin Infect Dis. (2011) 52 (9): 1100-1107.

We compared a Plasmodium falciparum histidine-rich-protein2 (PfHRP2)–based RDT and a Plasmodium lactate dehydrogenase (pLDH)–based RDT with routine microscopy of a peripheral blood slide and expert microscopy as a reference standard for the diagnosis of severe malaria in 1898 children who presented with severe febrile illness at 2 centers in Mozambique and Tanzania.

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African Burkitt Lymphoma: Age-Specific Risk and Correlations with Malaria Biomarkers

March 2, 2011 - 13:26 -- Patrick Sampao
Author(s): 
Benjamin Emmanuel., Esther Kawira., Sam M. Mbulaiteye., et al.
Reference: 
Am J Trop Med Hyg, Mar 2011; 84: 397 - 401.

Our findings suggest that concurrent infection with multiple malaria genotypes may be related to onset of African Burkitt lymphoma.

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Fast Track: Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial

November 15, 2010 - 13:43 -- Patrick Sampao
Author(s): 
Arjen M Dondorp, Caterina I Fanello, Juliet Mwanga-Amumpaire et al.
Reference: 
The Lancet, Volume 376, Issue 9753, 13 November 2010-19 November 2010, Pages 1647-1657

These data, together with a meta-analysis of all trials comparing artesunate and quinine, strongly suggest that parenteral artesunate should replace quinine as the treatment of choice for severe falciparum malaria worldwide.

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Open Access | Potential negative impacts and low effectiveness in the use of African annual killifish in the biocontrol of aquatic mosquito larvae in temporary water bodies

September 20, 2010 - 12:31 -- Patrick Sampao
Author(s): 
Reichard M., Watters BR., et al.
Reference: 
Parasites & Vectors 2010, 3:89 (16 September 2010)

Commentary and discussion on a recent paper promoting the use of Nothobranchius guentheri, a small African annual fish from the Island of Zanzibar as a tool to control mosquito larvae in temporary bodies of freshwater throughout Africa is presented.

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Open Access | Aestivation of the African Malaria Mosquito, Anopheles gambiae in the Sahel

September 3, 2010 - 08:22 -- Patrick Sampao
Author(s): 
Tovi L., Adama D., et al.
Reference: 
Am. J. Trop. Med. Hyg., 83(3), 2010, pp. 601-606

These results provide evidence that An. gambiae persists throughout the dry season by aestivation and open new questions for mosquito and parasite research.

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Review: Following the path of most resistance: dhps K540E dispersal in African Plasmodium falciparum

August 23, 2010 - 11:56 -- Patrick Sampao
Author(s): 
Inbarani Naidoo, Cally Roper
Reference: 
Trends in Parasitology, Volume 26, Issue 9, September 2010, Pages 447-456

We discuss whether there are common principles governing resistance dispersal in Africa and how these might guide surveillance in future.

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