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South America

NOT Open Access | Monitoring the Efficacy of Chloroquine-Primaquine Therapy for Uncomplicated Plasmodium vivax Malaria in the Main Transmission Hot Spot of Brazil

April 30, 2019 - 15:20 -- NOT Open Access
Author(s): 
Simone Ladeia-Andrade, Maria José Menezes, Taís Nóbrega de Sousa, Ana Carolina R. Silvino, Jaques F. de Carvalho Jr., Laís C. Salla, Odaílton A. Nery, Gladson N. P. de Melo, Rodrigo M. Corder, Priscila T. Rodrigues and Marcelo U. Ferreira
Reference: 
Antimicrob. Agents Chemother. April 2019 63:e01965-18

Emerging Plasmodium vivax resistance to chloroquine (CQ) may undermine malaria elimination efforts in South America. CQ-resistant P. vivax has been found in the major port city of Manaus but not in the main malaria hot spots across the Amazon Basin of Brazil, where CQ is routinely coadministered with primaquine (PQ) for radical cure of vivax malaria. Here we randomly assigned 204 uncomplicated vivax malaria patients from Juruá Valley, northwestern Brazil, to receive either sequential (arm 1) or concomitant (arm 2) CQ-PQ treatment.

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NOT Open Access | Pathological and molecular characterization of avian malaria in captive Magellanic penguins (Spheniscus magellanicus) in South America

February 6, 2019 - 15:39 -- NOT Open Access
Author(s): 
Paula Augusto Taunde, Matheus Viezzer Bianchi, Lívia Perles, Fernando Soares da Silva, Tainã Normanton Guim, Renan Alves Stadler, Marcos Rogério André, David Driemeier & Saulo Petinatti Pavarini
Reference: 
Parasitology Research February 2019, Volume 118, Issue 2, pp 599–606

Avian malaria is a mosquito-borne disease that affects multiple avian species and is caused by protozoans of the genus Plasmodium.

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Not Open Access | Parasitological and new molecular-phylogenetic characterization of the malaria parasite Plasmodium tejerai in South American penguins

January 31, 2013 - 04:37 -- NOT Open Access
Author(s): 
Patricia Silveira, Nayara O. Belo, Gustavo A. Lacorte, Cristiane K.M. Kolesnikovas, Ralph E.T. Vanstreels, Mário Steindel, José Luiz Catão-Dias, Gediminas Valkiūnas, Érika M. Braga
Reference: 
Parasitology International, Volume 62, Issue 2, April 2013, Pages 165-171
MalariaWorld

This study is the first report on mortality of Spheniscus magellanicus, penguin of South America, caused by Plasmodium tejerai, which was identified using morphological and molecular analyses.

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Plasmodium falciparum Field Isolates from South America Use an Atypical Red Blood Cell Invasion Pathway Associated with Invasion Ligand Polymorphisms

November 13, 2012 - 11:00 -- Open Access
Author(s): 
Mary Lopez-Perez, Elizabeth Villasis, Ricardo L. D. Machado, Marinete M. Póvoa, Joseph M. Vinetz, Silvia Blair, Dionicia Gamboa, Sara Lustigman
Reference: 
PLoS ONE 7(10): e47913
MalariaWorld

Studies of Plasmodium falciparum invasion pathways in field isolates have been limited.

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Open Access | Multiple independent introductions of Plasmodium falciparum in South America

January 11, 2012 - 09:34 -- Kabogo Ndegwa
Author(s): 
Erhan Yalcindag, Eric Elguero, Franck Prugnolle, et al.
Reference: 
PNAS January 10, 2012 vol. 109 no. 2 511-516

MalariaWorldThe origin of Plasmodium falciparum in South America is controversial.

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Open Access | Novel strategies lead to pre-elimination of malaria in previously high-risk areas in Suriname, South America

January 11, 2012 - 08:49 -- Kabogo Ndegwa
Author(s): 
Hiwat H, Hardjopawiro LS, Takken W, Villegas L
Reference: 
Malaria Journal 2012, 11:10 (9 January 2012)

MalariaWorldThe novel strategies for malaria control introduced in Suriname within the MM-MP have led to a significant decrease in the national malaria burden.

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A reliable ex vivo invasion assay of human reticulocytes by Plasmodium vivax

October 4, 2011 - 06:32 -- Kabogo Ndegwa
Author(s): 
Bruce Russell, Rossarin Suwanarusk, Laurent Rénia, et al.
Reference: 
Blood September 29, 2011 vol. 118 no. 13 e74-e81

MalariaWorldCurrently, there are no reliable RBC invasion assays to guide the discovery of vaccines against Plasmodium vivax, the most prevalent malaria parasite in Asia and South America.

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