sub-saharan Africa

Research in progress: Evaluating Artemisinin-resistant Plasmodium falciparum malaria using the K13 propeller domain molecular biomarker

Hi,
I want to share my research observations (on artemisinin resistance in Plasmodium falciparum) with malaria Professionals in this scientific community and welcome your candid comments.

I am a Ph.D student working on surveillance for artemisinin-resistant Plasmodium falciparum in dried blood spots sampled from Nigeria. I sequenced the K13 propeller domain at Macrogen using the PCR primers published in Nature Ariey 2014 titled 'A molecular marker of artemisinin resistant Plasmodium falciparum malaria'.

Chemical composition and insecticidal activity of plant essential oils from Benin against Anopheles gambiae (Giles)

Tags:

Anopheles gambiae, Benin

Author(s):

Bossou AD, Mangelinckx S, Yedomonhan H, Boko PM, Akogbeto MC, De Kimpe N, Avlessi F, Sohounhloue DC

Reference:

Parasites & Vectors 2013, 6 :337 (3 December 2013)

Background

Insecticide resistance in sub-Saharan Africa and especially in Benin is a major public health issue hindering the control of the malaria vectors. Each Anopheles species has developed a resistance to one or several classes of the insecticides currently in use in the field. Therefore, it is urgent to find alternative compounds to conquer the vector. In this study, the efficacies of essential oils of nine plant species, which are traditionally used to avoid mosquito bites in Benin, were investigated.

Continent:

sub-saharan Africa

Coverage of intermittent preventive treatment and insecticide-treated nets for the control of malaria during pregnancy in sub-Saharan Africa: a synthesis and meta-analysis of national survey data, 2009–11

Tags:

malaria, pregnancy

Author(s):

Anna Maria van Eijk, Jenny Hill, David A Larsen, Jayne Webster, Richard W Steketee, Thomas P Eisele, Feiko O ter Kuile

Reference:

The Lancet Infectious Diseases, Volume 13, Issue 12, December 2013, Pages 1029-1042

We aimed to review the coverage of intermittent preventive treatment, insecticide-treated nets, and antenatal care for pregnant women in sub-Saharan Africa and to explore associations between coverage and individual and country-level factors, including the role of funding for malaria prevention.

Continent:

sub-saharan Africa

Why are IPTp coverage targets so elusive in sub-Saharan Africa? A systematic review of health system barriers

Tags:

malaria

Author(s):

Sylla Thiam, Victoria Kimotho, Patrick Gatonga

Reference:

Malaria Journal 2013, 12:353 (3 October 2013)

This review sought to consolidate scattered evidence as to the health system barriers for IPTp coverage in the continent.

Continent:

sub-saharan Africa

Lessons from Agriculture for the Sustainable Management of Malaria Vectors

Author(s):

Matthew B. Thomas, H. Charles J. Godfray, Andrew F. Read, Henk van den Berg, Bruce E. Tabashnik, Joop C. van Lenteren, Jeff K. Waage, Willem Takken

Reference:

PLoS Med 9(7)

MalariaWorld Current malaria vector control relies almost exclusively on killing adult mosquitoes with chemical insecticides deployed as either insecticide-treated nets (ITNs) or indoor residual sprays (IRS).

Continent:

sub-saharan Africa

Medical Condition:

malaria vectors

Medical Treatment:

pyrethroids

NOT Open Access | Review: Poor-quality antimalarial drugs in southeast Asia and sub-Saharan Africa

Author(s):

Gaurvika ML Nayyar, Joel G Breman, Paul N Newton, James Herrington

Reference:

The Lancet Infectious Diseases, Volume 12, Issue 6, June 2012, Pages 488-496

MalariaWorld We reviewed published and unpublished studies reporting chemical analyses and assessments of packaging of antimalarial drugs.

Continent:

Southeast Asia

sub-saharan Africa

Medical Treatment:

antimalarial

Open Access | Letter: Plasmodium falciparum in Asymptomatic Immigrants from Sub-Saharan Africa, Spain

Author(s):

Begoña Monge-Maillo, Francesca Norman, José Antonio Pérez-Molina, Marta Díaz-Menéndez, Jose Miguel Rubio, and Rogelio López-Vélez

Reference:

Emerging Infectious Diseases, Volume 18, Number 2—February 2012

MalariaWorld In 2010, we reviewed the medical records of 314 asymptomatic (defined as patients with no symptoms at the time of consultation) immigrants from sub-Saharan Africa who had settled in Spain, had not traveled to their countries of origin since arrival, and had been examined at the Tropical Medicine Unit (TMU) of the Ramon y Cajal Hospital in Madrid during the previous 5 years.

Person:

Immigrants

Continent:

sub-saharan Africa

Country:

Spain

Medical Condition:

Plasmodium falciparum

Open Access | The use of paediatric artemisinin combinations in sub-Saharan Africa: a snapshot questionnaire survey of health care personnel

Author(s):

Agnandji ST, Kurth F, Ramharter M, et al.

Reference:

Malaria Journal 2011, 10:365 (14 December 2011)

This snapshot questionnaire survey aimed to provide an overview on the current routine practices for the availability and use P-ACT as anti-malarial treatment for young children in sub-Saharan Africa.

Person:

health care personnel

Continent:

sub-saharan Africa

Medical Treatment:

Artemisinin

Hematologic Parameters in Pediatric Uncomplicated Plasmodium falciparum Malaria in Sub-Saharan Africa

Author(s):

Piero Olliaro, Abdoulaye Djimdé, Grant Dorsey, Corine Karema, Andreas Mårtensson, Jean-Louis Ndiaye, Sodiomon B. Sirima, Michel Vaillant and Julien Zwang

Reference:

Am J Trop Med Hyg 2011 85:619-625

MalariaWorld The risk of neutropenia increased with follow-up time independent of treatment outcome, and was lower with age, higher baseline parasitemia, and artemisinin combination treatment. These analyses provides information on hematologic variations caused by malaria.

Continent:

sub-saharan Africa

Medical Condition:

malaria

Plasmodium falciparum