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sub-saharan Africa

Research in progress: Evaluating Artemisinin-resistant Plasmodium falciparum malaria using the K13 propeller domain molecular biomarker

January 9, 2016 - 09:03 -- Olajoju Soniran

Hi,
I want to share my research observations (on artemisinin resistance in Plasmodium falciparum) with malaria Professionals in this scientific community and welcome your candid comments.

I am a Ph.D student working on surveillance for artemisinin-resistant Plasmodium falciparum in dried blood spots sampled from Nigeria. I sequenced the K13 propeller domain at Macrogen using the PCR primers published in Nature Ariey 2014 titled 'A molecular marker of artemisinin resistant Plasmodium falciparum malaria'.

Chemical composition and insecticidal activity of plant essential oils from Benin against Anopheles gambiae (Giles)

December 11, 2013 - 16:21 -- Open Access
Author(s): 
Bossou AD, Mangelinckx S, Yedomonhan H, Boko PM, Akogbeto MC, De Kimpe N, Avlessi F, Sohounhloue DC
Reference: 
Parasites & Vectors 2013, 6 :337 (3 December 2013)

Background

Insecticide resistance in sub-Saharan Africa and especially in Benin is a major public health issue hindering the control of the malaria vectors. Each Anopheles species has developed a resistance to one or several classes of the insecticides currently in use in the field. Therefore, it is urgent to find alternative compounds to conquer the vector. In this study, the efficacies of essential oils of nine plant species, which are traditionally used to avoid mosquito bites in Benin, were investigated.

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Coverage of intermittent preventive treatment and insecticide-treated nets for the control of malaria during pregnancy in sub-Saharan Africa: a synthesis and meta-analysis of national survey data, 2009–11

November 20, 2013 - 17:20 -- Open Access
Author(s): 
Anna Maria van Eijk, Jenny Hill, David A Larsen, Jayne Webster, Richard W Steketee, Thomas P Eisele, Feiko O ter Kuile
Reference: 
The Lancet Infectious Diseases, Volume 13, Issue 12, December 2013, Pages 1029-1042
MalariaWorld

We aimed to review the coverage of intermittent preventive treatment, insecticide-treated nets, and antenatal care for pregnant women in sub-Saharan Africa and to explore associations between coverage and individual and country-level factors, including the role of funding for malaria prevention.

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Why are IPTp coverage targets so elusive in sub-Saharan Africa? A systematic review of health system barriers

October 18, 2013 - 15:20 -- Open Access
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Author(s): 
Sylla Thiam, Victoria Kimotho, Patrick Gatonga
Reference: 
Malaria Journal 2013, 12:353 (3 October 2013)
MalariaWorld

This review sought to consolidate scattered evidence as to the health system barriers for IPTp coverage in the continent.

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Lessons from Agriculture for the Sustainable Management of Malaria Vectors

July 13, 2012 - 11:09 -- Patrick Sampao
Author(s): 
Matthew B. Thomas, H. Charles J. Godfray, Andrew F. Read, Henk van den Berg, Bruce E. Tabashnik, Joop C. van Lenteren, Jeff K. Waage, Willem Takken
Reference: 
PLoS Med 9(7)

MalariaWorldCurrent malaria vector control relies almost exclusively on killing adult mosquitoes with chemical insecticides deployed as either insecticide-treated nets (ITNs) or indoor residual sprays (IRS).

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NOT Open Access | Review: Poor-quality antimalarial drugs in southeast Asia and sub-Saharan Africa

May 23, 2012 - 12:54 -- Patrick Sampao
Author(s): 
Gaurvika ML Nayyar, Joel G Breman, Paul N Newton, James Herrington
Reference: 
The Lancet Infectious Diseases, Volume 12, Issue 6, June 2012, Pages 488-496

MalariaWorldWe reviewed published and unpublished studies reporting chemical analyses and assessments of packaging of antimalarial drugs.

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Open Access | Letter: Plasmodium falciparum in Asymptomatic Immigrants from Sub-Saharan Africa, Spain

February 2, 2012 - 11:26 -- Patrick Sampao
Author(s): 
Begoña Monge-Maillo, Francesca Norman, José Antonio Pérez-Molina, Marta Díaz-Menéndez, Jose Miguel Rubio, and Rogelio López-Vélez
Reference: 
Emerging Infectious Diseases, Volume 18, Number 2—February 2012

MalariaWorldIn 2010, we reviewed the medical records of 314 asymptomatic (defined as patients with no symptoms at the time of consultation) immigrants from sub-Saharan Africa who had settled in Spain, had not traveled to their countries of origin since arrival, and had been examined at the Tropical Medicine Unit (TMU) of the Ramon y Cajal Hospital in Madrid during the previous 5 years.

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Open Access | The use of paediatric artemisinin combinations in sub-Saharan Africa: a snapshot questionnaire survey of health care personnel

December 15, 2011 - 15:28 -- Patrick Sampao
Author(s): 
Agnandji ST, Kurth F, Ramharter M, et al.
Reference: 
Malaria Journal 2011, 10:365 (14 December 2011)

http://www.pnas.org/content/108/50/20113.abstractThis snapshot questionnaire survey aimed to provide an overview on the current routine practices for the availability and use P-ACT as anti-malarial treatment for young children in sub-Saharan Africa.

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Hematologic Parameters in Pediatric Uncomplicated Plasmodium falciparum Malaria in Sub-Saharan Africa

October 10, 2011 - 07:50 -- Patrick Sampao
Author(s): 
Piero Olliaro, Abdoulaye Djimdé, Grant Dorsey, Corine Karema, Andreas Mårtensson, Jean-Louis Ndiaye, Sodiomon B. Sirima, Michel Vaillant and Julien Zwang
Reference: 
Am J Trop Med Hyg 2011 85:619-625

MalariaWorldThe risk of neutropenia increased with follow-up time independent of treatment outcome, and was lower with age, higher baseline parasitemia, and artemisinin combination treatment. These analyses provides information on hematologic variations caused by malaria.

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Open Access | Patterns of chloroquine use and resistance in sub-Saharan Africa: a systematic review of household survey and molecular data

May 11, 2011 - 12:06 -- Patrick Sampao
Author(s): 
Anne EP Frosch, Meera Venkatesan, Miriam K Laufer
Reference: 
Malaria Journal 2011, 10:116 (9 May 2011)

This study demonstrates that in 2006-2007 chloroquine and SP continued to be used at high rates in many African countries.

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