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Latin America

Development of molecular assays to detect target-site mechanisms associated with insecticide resistance in malaria vectors from Latin America

June 24, 2019 - 15:51 -- Open Access
Author(s): 
Juan C. Lol, David Castañeda, Lucy Mackenzie-Impoinvil, Carla G. Romero, Audrey Lenhart and Norma R. Padilla
Reference: 
Malaria Journal 2019 18:202, 20 June 2019

Malaria remains an important public health problem in Latin America, and the development of insecticide resistance in malaria vectors poses a major threat to malaria elimination efforts. Monitoring of insecticide susceptibility and the determination of the mechanisms involved in insecticide resistance are needed to effectively guide the deployment of appropriate vector control measures. Here, molecular assays have been developed to screen for mutations associated with insecticide resistance on the voltage-gated sodium channel (VGSC) and acetylcholinesterase-1 (Ace-1) genes in four malaria vectors from Latin America.

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Plasmodium vivax congenital malaria in an area of very low endemicity in Guatemala: implications for clinical and epidemiological surveillance in a malaria elimination context

December 10, 2012 - 09:04 -- Open Access
Tags: 
Author(s): 
Castellanos ME, Bardají A, Menegon M, Mayor A, Desai M, Severini C, Menéndez C, Padilla N
Reference: 
Malaria Journal 2012, 11:411 (8 December 2012)
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This is a report of the first Plasmodium vivax congenital malaria case in Guatemala and the first case in Latin America with genotypical, histological and clinical characterization.

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Review: malaria chemoprophylaxis for travelers to latin america.

December 8, 2011 - 15:27 -- Patrick Sampao
Author(s): 
Steinhardt LC, Magill AJ, Arguin PM.
Reference: 
Am J Trop Med Hyg. 2011 Dec;85(6):1015-24.

MalariaWorldPrimaquine should be strongly considered for nonpregnant, G6PD-nondeficient patients traveling to vivax-endemic areas of Latin America, and it has the added benefit of being the only drug to protect against malaria relapses.

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