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Conference Report | MALVAC 2009: Progress and Challenges in Development of Whole Organism Malaria Vaccines for Endemic Countries, 3–4 June 2009, Dakar, Senegal

July 6, 2010 - 07:42 -- Patrick Sampao
M. Pinder, V.S. Moorthy, B.D. Akanmori, B. Genton, G.V. Brown
Vaccine, Volume 28, Issue 30, 5 July 2010, Pages 4695-4702

A group of leading scientists, clinical trialists and stakeholders, together with representatives of regulatory authorities including some from African countries, met recently to document the issues that will require detailed consideration to assess this promising approach. Questions related to scale-up, quality, purity and consistency of a manufacturing process using mosquitoes to generate a commercial product, and demonstration of the stability of attenuated sporozoites will need further work.

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