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gametocytes

Humoral immunity prevents clinical malaria during Plasmodium relapses without eliminating gametocytes

October 1, 2019 - 14:29 -- Open Access
Author(s): 
Chester J. Joyner, Cristiana F. A. Brito, Mary R. Galinski, et al.
Reference: 
PLoS Pathog 15(9): e1007974

Plasmodium relapses are attributed to the activation of dormant liver-stage parasites and are responsible for a significant number of recurring malaria blood-stage infections.

Medical Condition: 

Artesunate causes recrudescence, Artemisia however kills gametocytes

February 16, 2016 - 11:03 -- Pierre Lutgen

A paper from Mali published last week is alarming (AA Djimbe et al., Parasite, 2016. 23, 3). Artesunate does not clear mature gametocytes during oral artesunate treatment and does not prevent the appearance of new gametocytes. This confirms to a large extent the randomized, double blind, large scale clinical trials of Munyanga and Idumbo in Maniema-Congo end of last year (see www.malariaworld.org).

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