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Analysis of esterase enzyme activity in adults of the major malaria vector Anopheles funestus

March 10, 2016 - 13:44 -- Open Access
Dahan-Moss Y, Koekemoer L
Parasites & Vectors 2016, 9 :110 (27 February 2016)

The aim of this study was to analyse esterase activity levels at different ages during the life-span of adult Anopheles funestus Giles in order to better understand the complex biological processes in this species.

Bio-efficacy of new long-lasting insecticide-treated bed nets against Anopheles funestus and Anopheles gambiae from central and northern Mozambique

September 22, 2015 - 17:45 -- Open Access
Ana Abílio, Pelágio Marrune, Nilsa de Deus, Francisco Mbofana, Pedro Muianga, Ayubo Kampango
Malaria Journal 2015, 14:352 (17 September 2015)

The study shows evidence of considerable heterogeneity in both insecticide susceptibility and the level of bio-efficacy of commonly available types of LLINs against wild A. funestus and A. gambiae from Balama, Mocuba and Milange districts, located in north and centre of Mozambique.


Humans frequently exposed to a range of non-human primate malaria parasite species through the bites of Anopheles dirus mosquitoes in South-central Vietnam

July 21, 2015 - 16:44 -- Open Access
Maeno Y, Quang N, Culleton R, Kawai S, Masuda G, Nakazawa S, Marchand R
Parasites & Vectors 2015, 8 :376 (16 July 2015)

In this study we analysed the species composition of malarial sporozoites infecting the salivary glands of Anopheles dirus in order to determine their potential role as bridge vectors of Plasmodium parasites from monkeys to humans.


Knockdown resistance (kdr) mutations in Indian Anopheles culicifacies populations

June 24, 2015 - 15:40 -- Open Access
Dykes C, Kushwah R, Das M, Sharma S, Bhatt R, Veer V, Agrawal O, Adak T, Singh O
Parasites & Vectors 2015, 8 :333 (18 June 2015)

This vector is resistant to DDT in most parts of the country with indication of emerging resistance to pyrethroids. Since knockdown resistance (kdr) is known to confer cross-resistance between DDT and pyrethroids owing to a common target site of action, knowledge of prevalence of knockdown resistance (kdr) alleles is important from insecticide resistance management point of view.

Not Open Access | Anti-CD81 but not anti-SR-BI blocks Plasmodium falciparum liver infection in a humanized mouse model

May 23, 2015 - 10:07 -- NOT Open Access
Lander Foquet, Cornelus C. Hermsen, Lieven Verhoye, Geert-Jan van Gemert, Riccardo Cortese, Alfredo Nicosia, Robert W. Sauerwein, Geert Leroux-Roels and Philip Meuleman
J. Antimicrob. Chemother. (2015) 70 (6): 1784-1787

These observations confirm the role of CD81 in liver-stage malaria and question that of SR-BI. CD81 might be a valuable drug target for the prevention of malaria.

Plasmodium falciparum in the southeastern Atlantic forest: a challenge to the bromeliad-malaria paradigm?

April 27, 2015 - 12:48 -- Open Access
Gabriel Laporta, Marcelo Burattini, Debora Levy, Linah Fukuya, Tatiane de Oliveira, Luciana Maselli, Jan Conn, Eduardo Massad, Sergio Bydlowski, Maria Sallum
Malaria Journal 2015, 14:181 (25 April 2015)

These results show that P. falciparum actively circulates, in higher proportion than P. vivax, among Anopheles mosquitoes of fragments of the southeastern Brazilian Atlantic forest.


Airport malaria: report of four cases in Tunisia

February 25, 2015 - 15:53 -- Open Access
Emna Siala, Dhikrayet Gamara, Kalthoum Kallel, Jabeur Daaboub, Faiçal Zouiten, Sandrine Houzé, Aïda Bouratbine, Karim Aoun
Malaria Journal 2015, 14:42 (28 January 2015)

This indicates the need to consider malaria while examining airport employees or people living near international airports presenting with fever of unknown origin. It also stresses the need for effective spraying of aircrafts coming from malarious areas.


Not Open Access | Data from: Whole genome sequencing reveals absence of recent gene-flow and separate demographic histories for Anopheles punctulatus mosquitoes in Papua New Guinea

February 10, 2015 - 15:23 -- NOT Open Access
Logue K, Small S, Chan E, Reimer L, Siba P, Zimmerman P, Serre D
Dyrad 2015

Our analysis of more than 50 Mb of orthologous DNA sequences revealed no evidence of contemporary gene flow among these mosquitoes. In addition, investigation of the demography of two of the Anopheles punctulatus species revealed distinct population histories.

Not Open Access | Editorial Commentary: Ivermectin as a Complementary Strategy to Kill Mosquitoes and Stop Malaria Transmission?

January 14, 2015 - 18:08 -- NOT Open Access
Richard W. Steketee and Feiko O. ter Kuile
Clin Infect Dis. (2015) 60 (3): 366-368.

Thus, a systemic endectocidal drug like ivermectin, which can be given to both humans and animals and is toxic to Anopheles mosquitoes when they take a blood meal from a host that has recently received it, provides an intriguing opportunity to kill the remaining mosquitoes that avoid or survive our existing vector control interventions

NOT Open Access | Antiviral immunity of Anopheles gambiae is highly compartmentalized, with distinct roles for RNA interference and gut microbiota

January 14, 2015 - 18:05 -- NOT Open Access
Guillaume Carissimo, Emilie Pondeville, Kenneth D. Vernick, et al.
Proceedings of the National Academy of Sciences of the USA vol. 112 no. 2

We compare them with the responses of the post-midgut systemic compartment, which is the site of the subsequent disseminated viral infection. Normal viral infection of the midgut requires bacterial flora and is inhibited by the activities of immune deficiency (Imd), JAK/STAT, and Leu-rich repeat immune factors.


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