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anti-malarial drugs

Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance

October 8, 2019 - 15:16 -- Open Access
Author(s): 
Nicholas J. White
Reference: 
Malaria Journal 2019 18:338, 11 October 2019

Resistance threatens all our currently available anti-malarial drugs.

Deployment and utilization of next-generation sequencing of Plasmodium falciparum to guide anti-malarial drug policy decisions in sub-Saharan Africa: opportunities and challenges

September 10, 2019 - 15:29 -- Open Access
Author(s): 
Deus S. Ishengoma, Queen Saidi, Carol H. Sibley, Cally Roper and Michael Alifrangis
Reference: 
Malaria Journal 2019 18:267, 3 September 2019

Parasite resistance against anti-malarial drugs is a major threat to the ongoing malaria control and elimination strategies.

Structure–activity relationships in a series of antiplasmodial thieno[2,3-b]pyridines

March 26, 2019 - 15:50 -- Open Access
Author(s): 
Andreas Masch, Abed Nasereddin, Conrad Kunick, et al.
Reference: 
Malaria Journal 2019 18:89, 21 March 2019

The attachment of alkylamino side chains leads to the improvement of antiplasmodial activity and aqueous solubility of selective PfGSK-inhibitors belonging to the class of 4-phenylthieno[2,3-b]pyridines.

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Artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in Congolese children under 10 years old living in a suburban area: a randomized study

November 4, 2015 - 11:55 -- Open Access
Author(s): 
Mathieu Ndounga, Pembe Issamou Mayengue, Francine Ntoumi, et al.
Reference: 
Malaria Journal 2015, 14:423 (29 October 2015)

This first randomized study in Brazzaville confirmed the excellent efficacy of these co-formulated anti-malarial drugs in children.

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