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anti-malarial drugs

Structure–activity relationships in a series of antiplasmodial thieno[2,3-b]pyridines

March 26, 2019 - 15:50 -- Open Access
Andreas Masch, Abed Nasereddin, Conrad Kunick, et al.
Malaria Journal 2019 18:89, 21 March 2019

The attachment of alkylamino side chains leads to the improvement of antiplasmodial activity and aqueous solubility of selective PfGSK-inhibitors belonging to the class of 4-phenylthieno[2,3-b]pyridines.

Medical Condition: 

Artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in Congolese children under 10 years old living in a suburban area: a randomized study

November 4, 2015 - 11:55 -- Open Access
Mathieu Ndounga, Pembe Issamou Mayengue, Francine Ntoumi, et al.
Malaria Journal 2015, 14:423 (29 October 2015)

This first randomized study in Brazzaville confirmed the excellent efficacy of these co-formulated anti-malarial drugs in children.

Medical Treatment: 
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