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anopheles

Knowledge engagement in gene drive research for malaria control

April 30, 2019 - 15:29 -- Open Access
Author(s): 
Sarah Hartley, Delphine Thizy, Katie Ledingham, Mamadou Coulibaly, Abdoulaye Diabaté, Bakara Dicko, Samba Diop, Jonathan Kayondo, Annet Namukwaya, Barry Nourou, Léa Paré Toé
Reference: 
PLoS Negl Trop Dis 13(4): e0007233

Gene drive mosquitoes are a novel approach to vector control being developed to help tackle malaria. A gene drive increases the frequency of a desired gene and its phenotypic effect into a mosquito population through reproduction in relatively few generations [1]. Combining gene drive with the precision of gene editing, scientists are able to modify the Anopheles mosquito genome and push modifications through natural vector populations. 

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Medical Condition: 

Cell-traversal protein for ookinetes and sporozoites (CelTOS) formulated with potent TLR adjuvants induces high-affinity antibodies that inhibit Plasmodium falciparum infection in Anopheles stephensi

April 29, 2019 - 13:13 -- Open Access
Author(s): 
Sakineh Pirahmadi, Sedigheh Zakeri, Akram A. Mehrizi, Navid D. Djadid, Abbas-Ali Raz, Jafar J. Sani, Ronak Abbasi and Zahra Ghorbanzadeh
Reference: 
Malaria Journal 2019 18:146, 24 April 2019

Plasmodium falciparum parasite is the most deadly species of human malaria, and the development of an effective vaccine that prevents P. falciparum infection and transmission is a key target for malarial elimination and eradication programmes. P. falciparum cell-traversal protein for ookinetes and sporozoites (PfCelTOS) is an advanced vaccine candidate. A comparative study was performed to characterize the immune responses in BALB/c mouse immunized with Escherichia coli-expressed recombinant PfCelTOS (rPfCelTOS) in toll-like receptor (TLR)-based adjuvants, CpG and Poly I:C alone or in combination (CpG + Poly I:C), followed by the assessment of transmission-reducing activity (TRA) of anti-rPfCelTOS antibodies obtained from different vaccine groups in Anopheles stephensi.

Medical Condition: 

Not Open Access | Plasmodium: Yet More Don’ts

February 9, 2019 - 18:51 -- NOT Open Access
Author(s): 
Miles B. Markus
Reference: 
Trends in Parasitology, Letter| Volume 35, Issue 2, P101-102, February 01, 2019

Anopheline’ is both an adjective (‘anopheline mosquito’) and a noun. Don’t use an upper case ‘A’, except at the beginning of a sentence; and do not italicize the word as if it is a Latinized genus name.

Change in Anopheles richness and composition in response to artificial flooding during the creation of the Jirau hydroelectric dam in Porto Velho, Brazil

February 23, 2017 - 16:24 -- Open Access
Author(s): 
Moreno S. Rodrigures, Elis P. Batista, Alexandre A. Silva, Fábio M. Costa, Verissimo A. S. Neto and Luiz Herman S. Gil
Reference: 
Malaria Journal 2017 16:87, 22 February 2017

The continual monitoring of these vectors during the late operational phase may be useful in order to understand how anophelines will behave in this area.

Draft Genomes of Anopheles cracens and Anopheles maculatus: Comparison of Simian Malaria and Human Malaria Vectors in Peninsular Malaysia

July 19, 2016 - 15:15 -- Open Access
Author(s): 
Yee-Ling Lau, Wenn-Chyau Lee, Junhui Chen, Zhen Zhong, Jianbo Jian, Amirah Amir, Fei-Wen Cheong, Jia-Siang Sum, Mun-Yik Fong
Reference: 
PLoS ONE 11(6): e0157893

Anopheles cracens has been incriminated as the vector of human knowlesi malaria in peninsular Malaysia.

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Pilot longitudinal mosquito surveillance study in the Danube Delta Biosphere Reserve and the first reports of Anopheles algeriensis Theobald, 1903 and Aedes hungaricus Mihályi, 1955 for Romania

April 26, 2016 - 16:10 -- Open Access
Author(s): 
Török E, Tomazatos A, Lühken R, et al.
Reference: 
Parasites & Vectors 2016, 9 :196 (11 April 2016)

We initiated a longitudinal mosquito surveillance study with carbon dioxide-baited Heavy Duty Encephalitis Vector Survey traps at four sampling sites to analyse the spatio-temporal pattern of the (i) mosquito species composition and diversity, (ii) functional groups of mosquitoes (oviposition sites, overwintering stage, and number of generations), and (iii) the occurrence of potential West Nile virus (WNV) vectors.

Behaviour and molecular identification of Anopheles malaria vectors in Jayapura district, Papua province, Indonesia

April 8, 2016 - 17:07 -- Open Access
Author(s): 
Brandy St. Laurent, Sukowati Supratman, Neil F. Lobo, et al.
Reference: 
Malaria Journal 2016 15:192, 8 April 2016

The vector composition in Papua, Indonesia is consistent with certain northern areas of PNG, but the behaviours of anophelines sampled in this region, such as early and indoor human biting of An. farauti 4, may enable them to act as major vectors of malaria.

Malaria incidence and entomological findings in an area targeted for a cluster-randomized controlled trial to prevent malaria in Ethiopia: results from a pilot study

March 10, 2016 - 17:19 -- Open Access
Author(s): 
Taye Gari, Oljira Kenea, Bernt Lindtjørn, et al.
Reference: 
Malaria Journal 2016 15:145, 8 March 2016

This study showed a high variation in malaria incidence and Anopheles between kebeles.

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Analysis of esterase enzyme activity in adults of the major malaria vector Anopheles funestus

March 10, 2016 - 13:44 -- Open Access
Author(s): 
Dahan-Moss Y, Koekemoer L
Reference: 
Parasites & Vectors 2016, 9 :110 (27 February 2016)

The aim of this study was to analyse esterase activity levels at different ages during the life-span of adult Anopheles funestus Giles in order to better understand the complex biological processes in this species.

Bio-efficacy of new long-lasting insecticide-treated bed nets against Anopheles funestus and Anopheles gambiae from central and northern Mozambique

September 22, 2015 - 17:45 -- Open Access
Author(s): 
Ana Abílio, Pelágio Marrune, Nilsa de Deus, Francisco Mbofana, Pedro Muianga, Ayubo Kampango
Reference: 
Malaria Journal 2015, 14:352 (17 September 2015)

The study shows evidence of considerable heterogeneity in both insecticide susceptibility and the level of bio-efficacy of commonly available types of LLINs against wild A. funestus and A. gambiae from Balama, Mocuba and Milange districts, located in north and centre of Mozambique.

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