The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10493 malaria professionals are enjoying the free benefits of MalariaWorld today

anopheles

NOT Open Access | Long-lasting insecticidal nets and the quest for malaria eradication: a mathematical modeling approach

May 25, 2020 - 08:13 -- NOT Open Access
Author(s): 
Enahoro I, Eikenberry S, Gumel AB, Huijben S, Paaijmans K
Reference: 
J Math Biol. 2020 May 23

Recent dramatic declines in global malaria burden and mortality can be largely attributed to the large-scale deployment of insecticidal-based measures, namely long-lasting insecticidal nets (LLINs) and indoor residual spraying. However, the sustainability of these gains, and the feasibility of global malaria eradication by 2040, may be affected by increasing insecticide resistance among the Anopheles malaria vector.

A steroid hormone agonist reduces female fitness in insecticide-resistant Anopheles populations

April 13, 2020 - 15:21 -- Open Access
Author(s): 
Brown F, Paton DG, Catteruccia F, Ranson H, Ingham VA
Reference: 
Insect Biochem Mol Biol. 2020 Apr 7:103372

Insecticide based vector control tools such as insecticide treated bednets and indoor residual spraying represent the cornerstones of malaria control programs. Resistance to chemistries used in these programs is now widespread and represents a significant threat to the gains seen in reducing malaria-related morbidity and mortality.

NOT Open Access | Neotropical Anopheles (Kerteszia) mosquitoes associated with bromeliad-malaria transmission in a changing world

March 2, 2020 - 14:10 -- NOT Open Access
Author(s): 
Multini LC, Wilke ABB, Marrelli MT
Reference: 
Acta Tropica, 21 February 2020, 105413

Kerteszia is a neotropical subgenus of Anopheles composed of 12 species. The species in this subgenus are strongly associated with humid forests rich in epiphytic bromeliads. Forest fragmentation and anthropogenic changes can therefore have a negative impact on the abundance and survival of these mosquito species. Within this subgenus, four species are considered primary vectors of malaria: An. cruzii, An. bellator, An. homunculus and An. neivai. Malaria cases associated with Kerteszia species are often referred to as bromeliad malaria, a type of malaria reported to be endemic in the coastal rainforest of the neotropical region since the end of the nineteenth century.

Molecular characterization of RNase III protein of Asaia sp. for developing a robust RNAi-based paratransgensis tool to affect the sexual life-cycle of Plasmodium or Anopheles fitness

February 11, 2020 - 15:47 -- Open Access
Author(s): 
Majid Asgari, Mahdokht Ilbeigikhamsehnejad, Elham Rismani, Navid Dinparast Djadid, Abbasali Raz
Reference: 
Parasit Vectors. 2020; 13:42

According to scientific recommendations, paratransgenesis is one of the solutions for improving the effectiveness of the Global Malaria Eradication Programme. In paratransgenesis, symbiont microorganisms are used for distorting or blocking the parasite life-cycle, affecting the fitness and longevity of vectors or reducing the vectorial competence. It has been revealed recently that bacteria could be used as potent tools for double stranded RNA production and delivery to insects. Moreover, findings showed that RNase III mutant bacteria are more competent for this aim. Asaia spp. have been introduced as potent paratransgenesis candidates for combating malaria and, based on their specific features for this goal, could be considered as effective dsRNA production and delivery tools to Anopheles spp. Therefore, we decided to characterize the rnc gene and its related protein to provide the basic required information for creating an RNase III mutant Asaia bacterium.

IgG antibody response against Anopheles salivary gland proteins in asymptomatic Plasmodium infections in Narino, Colombia

January 27, 2020 - 13:37 -- Open Access
Author(s): 
Jehidys Montiel, Luisa F. Carbal, Alberto Tobón-Castaño, Gissella M. Vásquez, Michael L. Fisher and Berlin Londono-Rentería
Reference: 
Malaria Journal 2020 19:42, 23 January 2020

The humoral immune response against Anopheles salivary glands proteins in the vertebrate host can reflect the intensity of exposure to Anopheles bites and the risk of Plasmodium infection. In Colombia, the identification of exposure biomarkers is necessary due to the several Anopheles species circulating. The purpose of this study was to evaluate risk of malaria infection by measuring antibody responses against salivary glands extracts from Anopheles (Nyssorhynchus) albimanus and Anopheles (Nys.) darlingi and also against the gSG6-P1 peptide of Anopheles gambiae in people residing in a malaria endemic area in the Colombian Pacific coast.

Gene copy number and function of the APL1 immune factor changed during Anopheles evolution

January 15, 2020 - 14:52 -- Open Access
Author(s): 
Mitri C, Bischoff E, Eiglmeier K, Holm I, Dieme C, Brito-Fravallo E, Raz A, Zakeri S, Nejad MIK, Djadid ND, Vernick KD, Riehle MM
Reference: 
Parasites Vectors 13, 18 (2020)

The recent reference genome assembly and annotation of the Asian malaria vector Anopheles stephensi detected only one gene encoding the leucine-rich repeat immune factor APL1, while in the Anopheles gambiae and sibling Anopheles coluzzii, APL1 factors are encoded by a family of three paralogs. The phylogeny and biological function of the unique APL1 gene in An. stephensi have not yet been specifically examined.

Not Open Access | Field Efficacy of VectoMax FG and VectoLex CG Biological Larvicides for Malaria Vector Control in Northwestern Brazil

November 30, 2019 - 15:16 -- NOT Open Access
Author(s): 
Fontoura PS, da Costa AS, Ribeiro FS, Ferreira MS, Castro MC, Ferreira MU
Reference: 
J Med Entomol. 2019 Nov 21. pii: tjz220

Despite historical and contemporary evidence of its effectiveness, larval source management with insecticides remains little used by most malaria control programs worldwide. Here we show that environmentally safe biological larvicides under field conditions can significantly reduce anopheline larval density in fish farming ponds that have became major larval habitats across the Amazon Basin.

Country: 

NOT Open Access | Functional analysis of the three major PGRPLC isoforms in the midgut of the malaria mosquito Anopheles coluzzii

November 26, 2019 - 13:30 -- NOT Open Access
Author(s): 
Rodgers FH, Cai JA, Pitaluga AN, Mengin-Lecreulx D, Gendrin M, Christophides GK
Reference: 
Insect Biochemistry and Molecular Biology, 21 November 2019, 103288

Peptidoglycan recognition proteins (PGRPs) constitute the primary means of bacterial recognition in insects. Recent work in the model organism Drosophila has revealed the mechanisms by which the complement of PGRPs refine the sensitivity of different tissues to bacterial elicitors, permitting the persistence of commensal bacteria in the gut whilst maintaining vigilance against bacterial infection.

The male mosquito contribution towards malaria transmission: Mating influences the Anopheles female midgut transcriptome and increases female susceptibility to human malaria parasites

November 18, 2019 - 16:18 -- Open Access
Author(s): 
Farah Aida Dahalan, Thomas S. Churcher, Nikolai Windbichler, Mara K. N. Lawniczak
Reference: 
PLoS Pathog 15(11): e1008063

Mating causes dramatic changes in female physiology, behaviour, and immunity in many insects, inducing oogenesis, oviposition, and refractoriness to further mating. Females from the Anopheles gambiae species complex typically mate only once in their lifetime during which they receive sperm and seminal fluid proteins as well as a mating plug that contains the steroid hormone 20-hydroxyecdysone.

Medical Condition: 

Evaluating synthetic odours and trap designs for monitoring Anopheles farauti in Queensland, Australia

September 10, 2019 - 15:18 -- Open Access
Author(s): 
Bram van de Straat, Alexandra Hiscox, Willem Takken and Thomas R. Burkot
Reference: 
Malaria Journal 2019 18:299, 2 September 2019

Monitoring of malaria vectors is important for designing and maintaining effective control interventions as changes in vector-feeding habits can threaten the efficacy of interventions. At present, human landing catches remain the most common method for monitoring malaria vectors of the Anopheles punctulatus complex, including the Anopheles farauti group. The aims of this study were to evaluate the efficacy of different lures and fan-powered traps, including an odour blend that has been demonstrated to be attractive to African anophelines, in Queensland, Australia.

Country: 

Pages

Subscribe to RSS - anopheles