The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10750 malaria professionals are enjoying the free benefits of MalariaWorld today

insecticide resistance

The making of a PNAS paper...here's our story

September 3, 2015 - 20:35 -- Bart G.J. Knols

Once a scientific paper is published online and you can download a pdf of it, this addictive and magnificent feeling gets on to you. This is the fruit of all the hard work: first to get the funding to undertake the research, then the hard work to actually perform all the research, then the hard work to write up the manuscript, then the submission, the reviews, the rebuttal, and eventually acceptance followed by proof reading and then publication. The route from thinking up research to publishing about it is long, tedious, and really hard work. But why don't we ever talk about this route? Why do we publish our papers but don't tell our peers more about how we got there? The fun parts, the sweat and tears, or even the fights? This week we published an article in the Proceedings of the National Academy of Sciences USA (PNAS; attached below). And here's the story you don't know when you read the paper...

Insecticide resistance status of indoor and outdoor resting malaria vectors in a highland and lowland site in Western Kenya

March 2, 2021 - 15:19 -- Open Access
Author(s): 
Owuor KO, Machani MG, Mukabana WR, Munga SO, Yan G, Ochomo E, Afrane YA
Reference: 
PLoS One. 2021 Mar 1;16(3):e0240771

Long Lasting Insecticidal Nets (LLINs) and indoor residual spraying (IRS) represent powerful tools for controlling malaria vectors in sub-Saharan Africa. The success of these interventions relies on their capability to inhibit indoor feeding and resting of malaria mosquitoes. This study sought to understand the interaction of insecticide resistance with indoor and outdoor resting behavioral responses of malaria vectors from Western Kenya.

Malaria vectors diversity, insecticide resistance and transmission during the rainy season in peri-urban villages of south-western Burkina Faso

January 27, 2021 - 15:52 -- Open Access
Author(s): 
Dieudonné Diloma Soma, Serge Bèwadéyir Poda, Roch Kounbobr Dabiré, et al.
Reference: 
Malaria Journal 2021 20:63, 25 January 2021

This study reports an updated description on malaria vector diversity, behaviour, insecticide resistance and malaria transmission in the Diébougou and Dano peri-urban areas, Burkina Faso.

Monitoring insecticide resistance in malaria vectors in Shandong Province: approaching malaria elimination

December 3, 2020 - 13:27 -- Open Access
Author(s): 
Cheng P, Liu L, Lv Y, Wang H, Gong M, Liu H
Reference: 
J Vector Ecol. 2020 Dec;45(2):380-383

Since the malaria elimination program was launched in China in 2010, the number of local infections has declined from 4,262 in 2010 to none in 2017, indicating remarkable achievements for prevention and treatment (Zhang et al. 2018). Shandong Province is a malaria‐endemic area, and vivax malaria is prevalent throughout the province.

Identification of main malaria vectors and their insecticide resistance profile in internally displaced and indigenous communities in Eastern Democratic Republic of the Congo (DRC)

November 24, 2020 - 14:56 -- Open Access
Author(s): 
Jeanine A. C. M. Loonen, Dominic B. Dery, Bertin Z. Musaka, Janvier B. Bandibabone, Teun Bousema, Marit van Lenthe, Biserka Pop-Stefanija, Jean-François Fesselet and Constantianus J. M. Koenraadt
Reference: 
Malaria Journal 2020 19:425, 23 November 2020

Malaria remains a major public health concern in the Democratic Republic of the Congo (DRC) and its control is affected by recurrent conflicts. Médecins Sans Frontières (MSF) initiated several studies to better understand the unprecedented incidence of malaria to effectively target and implement interventions in emergency settings. The current study evaluated the main vector species involved in malaria transmission and their resistance to insecticides, with the aim to propose the most effective tools and strategies for control of local malaria vectors.

Spatial Anopheles arabiensis (Diptera: Culicidae) insecticide resistance patterns across malaria-endemic regions of Botswana

November 24, 2020 - 13:44 -- Open Access
Author(s): 
Mmabaledi Buxton, Ryan J. Wasserman and Casper Nyamukondiwa
Reference: 
Malaria Journal 2020 19:415, 19 November 2020

Since the advent of the Green Revolution, pesticides have played an important role in the global management of invertebrate pests including vector mosquitoes. Despite optimal efficacy, insects often display insensitivity to synthetic insecticides owing to prolonged exposure that may select for resistance development. Such insecticide insensitivity may regress national and regional coordination in mosquito vector management and indeed malaria control. In Botswana, prolonged use of synthetic insecticides against malaria vectors have been practiced without monitoring of targeted mosquito species susceptibility status.

Multiple insecticide resistance target sites in adult field strains of An. gambiae (s.l.) from southeastern Senegal

November 14, 2020 - 16:15 -- Open Access
Author(s): 
Diouf EH, Niang EHA, Samb B, Diagne CT, Diouf M, Konaté A, Dia I, Faye O, Konaté L
Reference: 
Parasit Vectors. 2020 Nov 11;13(1):567

High coverage of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) are the cornerstones of vector control strategy in Senegal where insecticide resistance by the target vectors species is a great of concern. This study explores insecticide susceptibility profile and target-site mutations mechanisms within the Anopheles gambiae complex in southeastern Senegal.

Comparative assessment of insecticide resistance phenotypes in two major malaria vectors, Anopheles funestus and Anopheles arabiensis in south-eastern Tanzania

November 14, 2020 - 16:00 -- Open Access
Author(s): 
Polius G. Pinda, Claudia Eichenberger, Halfan S. Ngowo, Dickson S. Msaky, Said Abbasi, Japhet Kihonda, Hamis Bwanaly and Fredros O. Okumu
Reference: 
Malaria Journal 2020 19:408, 11 November 2020

Long-lasting insecticide-treated nets (LLINs) and indoor residual spraying (IRS) have greatly reduced malaria transmission in sub-Saharan Africa, but are threatened by insecticide resistance. In south-eastern Tanzania, pyrethroid-resistant Anopheles funestus are now implicated in > 80% of malaria infections, even in villages where the species occurs at lower densities than the other vector, Anopheles arabiensis. This study compared the insecticide resistance phenotypes between the two malaria vectors in an area where pyrethroid-LLINs are widely used.

Reduced long-lasting insecticidal net efficacy and pyrethroid insecticide resistance are associated with over-expression of CYP6P4, CYP6P3 and CYP6Z1 in populations of Anopheles coluzzii from South-East Côte d'Ivoire

November 12, 2020 - 15:38 -- Open Access
Author(s): 
Meiwald A, Clark E, Kristan M, Edi C, Jeffries CL, Pelloquin B, Irish SR, Walker T, Messenger LA
Reference: 
J Infect Dis. 2020 Nov 11:jiaa699

Resistance to major public health insecticides in Côte d’Ivoire has intensified and now threatens the long-term effectiveness of malaria vector control interventions.

NOT Open Access | Cytochrome P450-based metabolic insecticide resistance in Anopheles and Aedes mosquito vectors: Muddying the waters

November 4, 2020 - 16:05 -- NOT Open Access
Author(s): 
Vontas J, Katsavou E, Mavridis K
Reference: 
Pestic Biochem Physiol. 2020 Nov;170:104666

Despite the substantial progress achieved in the characterization of cytochrome P450 (CYP) -based resistance mechanisms in mosquitoes, a number of questions remain unanswered. These include: (i) the regulation and physiology of resistance conferring CYPs; (ii) the actual contribution of CYPs in resistance alone or in combination with other detoxification partners or other resistance mechanisms; (iii) the association between overexpression levels and allelic variation, with the catalytic activity and the intensity of resistance and (iv) the true value of molecular diagnostics targeting CYP markers, for driving decision making in the frame of Insecticide Resistance Management applications.

Pages

Subscribe to RSS - insecticide resistance