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rapid diagnostic test (RDT)

Malaria infection prevalence and sensitivity of reactive case detection in zanzibar

June 15, 2020 - 15:43 -- Open Access
Author(s): 
Stuck L, Fakih BS, Yukich J, et al.
Reference: 
Int J Infect Dis. 2020 Jun 10:S1201-9712(20)30452-5

Reactive case detection (RCD) is a commonly used strategy for malaria surveillance and response in elimination settings. Many approaches to RCD assume detectable infections are clustered within and around homes of passively detected cases (index households), which has been evaluated in a number of settings with disparate results.

Uncovering hidden pfhrp2/3 deletion Plasmodium falciparum

June 10, 2020 - 15:08 -- Open Access
Author(s): 
Kobayashi T
Reference: 
EBioMedicine. 2020 Jun 5;56:102781

Deaths and transmission from malaria have declined significantly in the past decade, although the progress has somewhat stalled in recent years. Accurate and timely diagnosis is essential to providing adequate treatment to malaria cases. Plasmodium falciparum histidine-rich protein 2 (PfHRP2) based rapid diagnostic test (RDT) is widely used especially in Africa, where P. Falciparum accounts for 98%of estimated malaria cases. Despite its importance, reports of parasites lackingpfhrp2gene emerging across the globe are threatening the importance of this malaria diagnostic tool.

Risk Factors for Malaria Infection and Seropositivity in the Elimination Area of Grand'Anse, Haiti: A Case-Control Study among Febrile Individuals Seeking Treatment at Public Health Facilities

May 29, 2020 - 14:24 -- Open Access
Author(s): 
Ashton RA, Joseph V, Eisele TP, et al.
Reference: 
Am J Trop Med Hyg. 2020 May 26.

The island of Hispaniola aims to eliminate malaria by 2025; however, there are limited data to describe epidemiologic risk factors for malaria in this setting. A prospective case–control study was conducted at four health facilities in southwest Haiti, aiming to describe factors influencing the risk of current and past malaria infection. Cases were defined as individuals attending facilities with current or recent fever and positive malaria rapid diagnostic test (RDT), whereas controls were those with current or recent fever and RDT negative.

Housing Improvements and Malaria Risk in Sub-Saharan Africa: A Multi-Country Analysis of Survey Data

March 16, 2017 - 16:21 -- Open Access
Author(s): 
Lucy S. Tusting, Christian Bottomley, Harry Gibson, Immo Kleinschmidt, Andrew J. Tatem, Steve W. Lindsay, Peter W. Gething
Reference: 
PLoS Med 14(2): e1002234

Housing quality is an important risk factor for malaria infection across the spectrum of malaria endemicity in SSA, with a strength of association between housing quality and malaria similar to that observed between ITN use and malaria.

Medical Treatment: 

A comparison of malaria prevalence, control and management strategies in irrigated and non-irrigated areas in eastern Kenya

August 16, 2016 - 15:47 -- Open Access
Author(s): 
John Muthii Muriuki, Philip Kitala, Gerald Muchemi, Ian Njeru, Joan Karanja and Bernard Bett
Reference: 
Malaria Journal 2016 15:402, 11 August 2016

The residents of Bura irrigation scheme were more likely to be infected compared to those living in the non-irrigated area of Ijara.

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Glucose-6-phosphate dehydrogenase deficiency among Yemeni children residing in malaria-endemic areas of Hodeidah governorate and evaluation of a rapid diagnostic test for its detection

June 27, 2016 - 17:52 -- Open Access
Author(s): 
Rashad Abdul-Ghani, Mohammed A. K. Mahdy, Ali Alhaj, et al.
Reference: 
Malaria Journal 2016 15:327, 21 June 2016

G6PD deficiency with enzyme activity of ≤60 % of normal is prevalent among 12.0 % of children residing in malaria-endemic areas of Hodeidah governorate, with 2.3 % having severe G6PD deficiency.

Feasibility, acceptability and impact of integrating malaria rapid diagnostic tests and pre-referral rectal artesunate into the integrated community case management programme. A pilot study in Mchinji district, Malawi

March 22, 2016 - 17:37 -- Open Access
Author(s): 
Themba B. Phiri, Blessings N. Kaunda-Khangamwa, Andrew Bauleni, Tiyese Chimuna, David Melody, Humphreys Kalengamaliro, John H. Sande, Humphreys Kampira Nsona and Don P. Mathanga
Reference: 
Malaria Journal 2016 15:177, 21 March 2016

Integration of RDTs and pre-referral rectal at artesunate community level is both feasible and acceptable.

Country: 

Health workers’ compliance to rapid diagnostic tests (RDTs) to guide malaria treatment: a systematic review and meta-analysis

March 16, 2016 - 17:48 -- Open Access
Author(s): 
Alinune N. Kabaghe, Benjamin J. Visser, Rene Spijker, Kamija S. Phiri, Martin P. Grobusch and Michèle van Vugt
Reference: 
Malaria Journal 2016 15:163, 15 March 2016

With regard to published data, compliance to RDT appears to be generally fair in sub-Saharan Africa; compliance to negative results will need to improve to prevent mismanagement of patients and overprescribing of anti-malarial drugs.

Medical Treatment: 

Drug seller adherence to clinical protocols with integrated management of malaria, pneumonia and diarrhoea at drug shops in Uganda

July 17, 2015 - 10:04 -- Open Access
Author(s): 
Phyllis Awor, Henry Wamani, Thorkild Tylleskar, Stefan Peterson
Reference: 
Malaria Journal 2015, 14:277 (16 July 2015)

With the introduction of the iCCM intervention at drug shops in Eastern Uganda, it was possible to achieve high adherence to the treatment protocols, which is likely compatible with increased quality of care.

Country: 
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