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Anopheles gambiae

A significant association between deltamethrin resistance, Plasmodium falciparum infection and the Vgsc-1014S resistance mutation in Anopheles gambiae highlights the epidemiological importance of resistance markers

May 25, 2016 - 17:43 -- Open Access
Bilali Kabula, Patrick Tungu, Emily J. Rippon, Keith Steen, William Kisinza, Stephen Magesa, Franklin Mosha and Martin James Donnelly
Malaria Journal 2016 15:289, 23 May 2016

One marker, Vgsc-1014S, was associated with insecticide resistance and P. falciparum infection in wild-caught mixed aged populations of A. gambiae s.s. thereby showing how resistance may directly impact transmission.


How important is the angle of tilt in the WHO cone bioassay?

May 2, 2016 - 06:28 -- Open Access
Henry F. Owusu and Pie Müller
Malaria Journal 2016 15:243, 27 April 2016

The angle at which the test is performed significantly affects the amount of time mosquitoes spend resting on the nets, and subsequently mortality.

Increasing outdoor host-seeking in Anopheles gambiae over 6 years of vector control on Bioko Island

April 26, 2016 - 18:30 -- Open Access
Jacob I. Meyers, Sharmila Pathikonda, Michel A. Slotman, et al.
Malaria Journal 2016 15:239, 26 April 2016

While vector control on Bioko Island has succeeded in substantial reduction in overall vector biting rates, populations of An. coluzzii and An. melas persist.

Effects of larvicidal and larval nutritional stresses on Anopheles gambiae development, survival and competence for Plasmodium falciparum

April 26, 2016 - 16:19 -- Open Access
Vantaux A, Ouattarra I, Lefèvre T, Dabiré K
Parasites & Vectors 2016, 9 :226 (23 April 2016)

We investigated how two environmental stresses (larviciding and nutritional stress) interact to affect Anopheles gambiae (previously An. gambiae S molecular form) life history traits and its susceptibility for field isolates of its natural malaria agent Plasmodium falciparum.

Overloading the immunity of the mosquito Anopheles gambiae with multiple immune challenges

April 21, 2016 - 16:29 -- Open Access
Barreaux A, Barreaux P, Koella J
Parasites & Vectors 2016, 9 :210 (14 April 2016)

We considered these questions with the mosquito Anopheles gambiae by inoculating individuals simultaneously with one, two or three negatively charged Sephadex beads, and estimating the melanisation as the darkness of the bead (which ranges from about 0 for unmelanised beads to 100 for the most melanised beads of our experiment).

Radical remodeling of the Y chromosome in a recent radiation of malaria mosquitoes

April 13, 2016 - 16:17 -- Open Access
Andrew Brantley Hall, Philippos-Aris Papathanos, Nora J. Besansky, et al.
PNAS April 12, 2016, vol. 113 no. 15

Y chromosomes control essential male functions in many species, including sex determination and fertility.

Malaria vector populations across ecological zones in Guinea Conakry and Mali, West Africa

April 8, 2016 - 17:08 -- Open Access
Boubacar Coulibaly, Raymond Kone, Michelle M. Riehle, et al.
Malaria Journal 2016 15:191, 8 April 2016

The study represents detailed vector characterization from an understudied area in West Africa with endemic malaria transmission.


Genomic signatures of population decline in the malaria mosquito Anopheles gambiae

March 29, 2016 - 17:17 -- Open Access
Samantha M. O’Loughlin, Stephen M. Magesa, Charles Mbogo, Franklin Mosha, Janet Midega and Austin Burt
Malaria Journal 2016 15:182, 24 March 2016

These results support the hypothesis that the recent decline in An. gambiae was driven by the rollout of bed nets.

Medical Treatment: 

Not Open Access | Identifying targets of selection in mosaic genomes with machine learning: applications in Anopheles gambiae for detecting sites within locally adapted chromosomal inversions

March 22, 2016 - 13:18 -- NOT Open Access
Qixin He, L Lacey Knowles
Molecular Ecology

Here we develop a new approach that uses discriminant functions informed from inversion-specific expectations to classify loci that are under selection (or drift). 

Low prevalence of Plasmodium and absence of malaria transmission in Conakry, Guinea: prospects for elimination

March 19, 2016 - 19:40 -- Open Access
Bernard L. Kouassi, Dziedzom K. de Souza, Benjamin G. Koudou, et al.
Malaria Journal 2016 15:175, 18 March 2016

The low density of larval and adult stages of Anopheles mosquitoes, the absence of infected An. gambiae species and the low prevalence of Plasmodium in under 5-year-old children are important features that might facilitate malaria elimination in Conakry.


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