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heterocyclic analogs

Not Open Access | Recent advances in novel heterocyclic scaffolds for the treatment of drug-resistant malaria

March 18, 2015 - 12:37 -- NOT Open Access
Sahil Kumar, Rajesh K. Singh, Babita Patial, Sachin Goyal, T. R. Bhardwaj
Journal of Enzyme Inhibition and Medicinal Chemistry, March 16, 2015

This review presents recent modifications of 4-aminoquinoline and 8-aminoquinolone rings as leads to novel active molecules which are under clinical trials. The review also encompasses the other heterocyclic compounds emerged as potential antimalarial agents with promising results such as acridinediones and acridinone analogues, pyridines and quinolones as antimalarials.

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