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pregnant women

Malaria knowledge and experiences with community health workers among recently pregnant women in Malawi

April 17, 2020 - 14:24 -- Open Access
Ashley Malpass, Jobiba Chinkhumba, Julie R. Gutman, et al.
Malaria Journal 2020 19:154, 15 April 2020

The World Health Organization recommends three or more doses of intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) to mitigate the negative effects of malaria in pregnancy (MIP). Many pregnant women in Malawi are not receiving the recommended number of doses. Community delivery of IPTp (cIPTp) is being piloted as a new approach to increase coverage. This survey assessed recently pregnant women’s knowledge of MIP and their experiences with community health workers (CHWs) prior to implementing cIPTp.

Trend of declining bed net utilization among pregnant women in Ethiopia: new data from the Arba Minch Health and Demographic Surveillance System, 2010–2016

April 13, 2020 - 13:42 -- Open Access
Teklemariam Gultie, Gistane Ayele, Alazar Baharu, et al.
Malaria Journal 2020 19:142, 8 April 2020

Bed net utilization is one of the important methods of malaria prevention. Malaria during pregnancy is one of the fatal diseases which mostly leads to the death of the mother and the fetus. Some of the complications of malaria during pregnancy are: intrauterine growth restrictions, intrauterine fetal death, and stillbirth. The main challenge of malaria treatment is that most of the anti-malarial drugs are not safe to use during pregnancy. The use of bed net is the most effective method of prevention of malaria during pregnancy. There is a paucity of information on bed net utilization among pregnant women in the study setting. Hence, this study aims to assess the trends of bed net utilization among pregnant women in Arba Minch Health and Demography Surveillance Site (HDSS), Southern Ethiopia.

NOT Open Access | Regional variation and demographic factors associated with knowledge of malaria risk and prevention strategies among pregnant women in Nigeria

April 6, 2020 - 08:41 -- NOT Open Access
Iyanda AE, Osayomi T, Boakye KA, Lu Y
Women & Health, Volume 60, 2020 - Issue 4

Pregnant women and children are the most vulnerable populations for malaria infection. Yet, knowledge of risk, and preventive measures are poor among this population. Using the 2015 Nigeria Malaria Indicator Survey, we applied logit link function to estimate the associations of wealth status, educational attainment, and region of residence with malaria risk knowledge and prevention strategies (using a treated mosquito net and malaria drugs) among 739 Nigerian pregnant women aged 15–49 years.

NOT Open Access | Effect of drug pressure on promoting the emergence of antimalarial resistant parasites among pregnant women in Ghana

March 19, 2020 - 09:16 -- NOT Open Access
Tornyigah B, Coppée R, Houze P, Kusi KA, Adu B, Quakyi I, Coleman N, Mama A, Deloron P, Anang AK, Clain J, Tahar R, Ofori MF, Ndam NT
Antimicrob Agents Chemother. 2020 Mar 16. pii: AAC.02029-19

Continuous spread of antimalarial drug resistance is a threat to current chemotherapy efficacy. Therefore, characterizing the genetic diversity of drug resistance markers is needed to follow treatment effectiveness and further update control strategies. Here, we genotyped Plasmodium falciparum resistance gene markers associated with sulfadoxine-pyrimethamine (SP) and artemisinin-based combination therapy (ACT) in isolates from pregnant women in Ghana.

Effectiveness of Sulfadoxine-Pyrimethamine for Intermittent Preventive Treatment of Malaria and Adverse Birth Outcomes in Pregnant Women

March 18, 2020 - 14:43 -- Open Access
Mlugu EM, Minzi O, Asghar M, Färnert A, Kamuhabwa AAR, Aklillu E
Pathogens. 2020 Mar 11;9(3). pii: E207

Effectiveness of intermittent preventive treatment in pregnancy with sulfadoxine–pyrimethamine (IPTp-SP) for prevention of malaria and adverse birth outcomes can be compromised by parasites-resistance to sulfadoxine–pyrimethamine. This study prospectively evaluated the effectiveness of IPTp-SP in Southeast Tanzania. From January 2017 to May 2019, HIV-negative and malaria-negative (mRDT) pregnant women attending their first antenatal-care visit in the second or third trimester (n = 500) were enrolled to receive monthly IPTp-SP and followed the protocol till delivery.

Relationship between placenta malaria and mother to child transmission of HIV infection in pregnant women in South East Nigeria

March 3, 2020 - 12:58 -- Open Access
Ikechukwu I. Mbachu, Samson D. Ejikunle, Frederick Anolue, Chioma N. Mbachu, Ephraim Dike, Eke Ejikem and Chijioke Okeudo
Malaria Journal 2020 19:97, 27 February 2020

This study determined the rate of mother-to-child transmission (MTCT) of HIV among HIV positive women with placenta malaria and factors associated with placenta malaria.

Towards protective immune responses against malaria in pregnant women

February 17, 2020 - 12:17 -- Open Access
Daubenberger CA
Lancet Infect Dis. 2020 Feb 4. pii: S1473-3099(20)30002-5

Plasmodium falciparum infection was estimated to affect around 11 million pregnancies in 2018 in 38 countries in sub-Saharan Africa. Malaria-associated maternal anaemia is a major driver of low birthweight in newborn babies and WHO have estimated that malaria infections in pregnancy have resulted in an estimated 872 000 babies born with low birthweight in 2018.

Asymptomatic malaria infection among pregnant women attending antenatal care in malaria endemic areas of North-Shoa, Ethiopia: a cross-sectional study

February 14, 2020 - 16:41 -- Open Access
Daniel Getacher Feleke, Aderaw Adamu, Angesom Gebreweld, Melkam Tesfaye, Wondmagegn Demisiss and Genet Molla
Malaria Journal 2020 19:67, 11 February 2020

The effort to reduce the burden of malaria should target transmission in the community by accurate identification of asymptomatic infections. In malaria-endemic areas, asymptomatic malaria infection is still associated with complications. Malaria during pregnancy is characterized by anaemia and placental malaria, leading to low birth weight and perinatal morbidity and mortality. This study aimed to provide reliable data on the burden of asymptomatic malaria among pregnant women in malaria endemic areas of North-Shoa, Ethiopia.

The potential of pregnant women as a sentinel population for malaria surveillance

November 26, 2019 - 14:38 -- Open Access
Nina C. Brunner, Frank Chacky, Renata Mandike, Ally Mohamed, Manuela Runge, Sumaiyya G. Thawer, Amanda Ross, Penelope Vounatsou, Christian Lengeler, Fabrizio Molteni and Manuel W. Hetzel
Malaria Journal 2019 18:370, 21 November 2019

With increasing spatial heterogeneity of malaria transmission and a shift of the disease burden towards older children and adults, pregnant women attending antenatal care (ANC) have been proposed as a pragmatic sentinel population for malaria surveillance. However, the representativeness of routine ANC malaria test-positivity and its relationship with prevalence in other population subgroups are yet to be investigated.

Interactions between malaria and HIV infections in pregnant women: a first report of the magnitude, clinical and laboratory features, and predictive factors in Kinshasa, the Democratic Republic of Congo

March 7, 2015 - 09:46 -- Open Access
Roger D Wumba, Josué Zanga, Michel N Aloni, Kennedy Mbanzulu, Aimé Kahindo, Madone N Mandina, Mathilde B Ekila, Oussama Mouri, Eric Kendjo
Malaria Journal 2015, 14:82 (18 February 2015)

The aim of the study was to determine the magnitude, predictive factors, clinical, biologic and anthropometric consequences of malaria infection, HIV infection, and interactions between malaria and HIV infections in pregnant women.


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