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drug resistance

NOT Open Access | Within-Host Selection of Drug Resistance in a Mouse Model of Repeated Incomplete Malaria Treatment: Comparison between Atovaquone and Pyrimethamine

January 20, 2016 - 15:04 -- NOT Open Access
Author(s): 
Suci Nuralitha, Josephine E. Siregar, Din Syafruddin, Jessica Roelands, Jan Verhoef, Andy I. M. Hoepelman, and Sangkot Marzuki
Reference: 
Antimicrob. Agents Chemother. January 2016 vol. 60 no. 1 258-263

The evolutionary selection of malaria parasites within individual hosts is an important factor in the emergence of drug resistance but is still not well understood.

Effective Coverage and Systems Effectiveness for Malaria Case Management in Sub-Saharan African Countries

June 2, 2015 - 13:46 -- Open Access
Author(s): 
Katya Galactionova, Fabrizio Tediosi, Don de Savigny, Thomas Smith, Marcel Tanner
Reference: 
PLoS ONE 10(5): e0127818

Scale-up of malaria preventive and control interventions over the last decade resulted in substantial declines in mortality and morbidity from the disease in sub-Saharan Africa and many other parts of the world.

Frequency and correlates of malaria over-treatment in areas of differing malaria transmission: a cross-sectional study in rural Western Kenya

March 5, 2015 - 17:44 -- Open Access
Author(s): 
Frankline M Onchiri, Patricia B Pavlinac, Benson O Singa, Jacqueline M Naulikha, Elizabeth A Odundo, Carey Farquhar, Barbra A Richardson, Grace John-Stewart, Judd L Walson
Reference: 
Malaria Journal 2015, 14:97 (1 March 2015)

Malaria over-treatment was common, particularly in Homa Bay, where the prevalence of malaria was extremely high.

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