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sudan

Hematological indices and abnormalities among patients with uncomplicated falciparum malaria in Kosti city of the White Nile state, Sudan: a comparative study

June 1, 2021 - 15:47 -- Open Access
Author(s): 
Elkhalifa AME, Abdul-Ghani R, Tamomh AG, Eltaher NE, Ali NY, Ali MM, Bazie EA, KhirAlla A, DfaAlla FA, Alhasan OAM
Reference: 
BMC Infect Dis. 2021 May 31;21(1):507

Hematological abnormalities are common features in falciparum malaria but vary among different populations across countries. Therefore, we compared hematological indices and abnormalities between Plasmodium falciparum-infected patients and malaria-negative subjects in Kosti city of the White Nile State, Sudan.

Status of insecticide susceptibility in Anopheles arabiensis and detection of the knockdown resistance mutation (kdr) concerning agricultural practices from Northern Sudan state, Sudan

March 30, 2021 - 14:26 -- Open Access
Author(s): 
Korti MY, Ageep TB, Adam AI, Shitta KB, Hassan AA, Algadam AA, Baleela RM, Saad HA, Abuelmaali SA
Reference: 
J Genet Eng Biotechnol. 2021 Mar 29;19(1):49

Chemical control has been the most efficient method in mosquito control, the development of insecticide resistance in target populations has a significant impact on vector control. The use of agricultural pesticides may have a profound impact on the development of resistance in the field populations of malaria vectors. Our study focused on insecticide resistance and knockdown resistance (kdr) of Anopheles arabiensis populations from Northern Sudan, related to agricultural pesticide usage.

Molecular and morphological identification of suspected Plasmodium vivax vectors in Central and Eastern Sudan

March 10, 2021 - 14:49 -- Open Access
Author(s): 
Omnia Fathelrhman Abdelwhab, Arwa Elaagip, Musab M. Albsheer, Ayman Ahmed, Giacomo Maria Paganotti and Muzamil Mahdi Abdel Hamid
Reference: 
Malaria Journal 2021 20:132, 4 March 2021

In spite of the global effort to eliminate malaria, it remains the most significant vector-borne disease of humans. Plasmodium falciparum is the dominant malaria parasite in sub-Saharan Africa. However, Plasmodium vivax is becoming widely spread throughout Africa. The overuse of vector control methods has resulted in a remarkable change in the behaviour of mosquito that feeds on human as well as on vector composition. The aim of this study was to identify Anopheles mosquito species in vivax malaria endemic regions and to investigate their role in P. vivax circumsporozoite protein (Pvcsp) allele diversity.

Impact of placental malaria on maternal, placental and fetal cord responses and its role in pregnancy outcomes in women from Blue Nile State, Sudan

January 13, 2021 - 10:08 -- Open Access
Author(s): 
Samia Omer, Clara Franco-Jarava, Ali Noureldien, Mona Omer, Mutasim Abdelrahim, Israel Molina and Ishag Adam
Reference: 
Malaria Journal 2021 20:35, 9 January 2021

The sequestration of Plasmodium falciparum infected cells in the placenta results in placental malaria (PM). It activates the mother's immune cells and induces secretion of inflammatory cytokines, which might influence pregnancy outcomes. This study aims to investigate the cytokines (levels IL-4, IL-6, IL-10, IL-17A, and INF γ) in maternal peripheral, placental, and umbilical cord blood in response to PM and the extent to which this may influence maternal haemoglobin levels and birth weight.

A snapshot of Plasmodium falciparum malaria drug resistance markers in Sudan: a pilot study

November 10, 2020 - 14:22 -- Open Access
Author(s): 
Mohamed NS, Abdelbagi H, Sibley CH, et al.
Reference: 
BMC Res Notes. 2020 Nov 7;13(1):512

Malaria infection is still known to be a worldwide public health problem, especially in tropical and sub-tropical African countries like Sudan. A pilot study conducted to describe the trend of P. falciparum drug resistance markers in 2017–2018 in comparison to CQ and AS/SP eras in Sudan. The Pfcrt, Pfmdr-1, Pfdhfr, and Pfdhps genes were investigated. Data deposited by the worldwide antimalarial resistance network was consulted, and the molecular markers previously reported from Sudan were analyzed.

NOT Open Access | Community pharmacists' knowledge and practice regarding malaria and its treatment in Sudan: a cross-sectional survey

October 7, 2020 - 16:02 -- NOT Open Access
Author(s): 
Elhag EAA, Sulaiman SAS
Reference: 
Int J Clin Pharm. 2020 Oct 6

Malaria is one of the main causes of death in Sudan with high prevalence among males, children under five-year and pregnant women. In 2016 near 13% of hospital admissions in Sudan were due to malaria. Community pharmacist dispensing of antimalarial drugs without prescription and malaria self-treatment may lead to the development of drugs resistance and delay disease control. Objective To assess the knowledge and practice of community pharmacists regarding malaria and its treatment. Setting Community pharmacies in Khartoum State, Sudan.

Antimalarial drug resistance molecular makers of Plasmodium falciparum isolates from Sudan during 2015-2017

August 24, 2020 - 14:05 -- Open Access
Author(s): 
Hussien M, Abdel Hamid MM, Elamin EA, Hassan AO, Elaagip AH, Salama AHA, Abdelraheem MH, Mohamed AO
Reference: 
PLoS One. 2020 Aug 20;15(8):e0235401

Current malaria control and elimination strategies rely mainly on efficacious antimalarial drugs. However, drug resistance is a major threat facing malaria control programs. Determination of drug resistance molecular markers is useful in the monitoring and surveillance of malaria drug efficacy. This study aimed to determine the mutations and haplotypes frequencies of different genes linked with antimalarial drug resistance in certain areas in Sudan.

NOT Open Access | Congenital Malaria in Newborns Delivered to Mothers with Malaria-Infected Placenta in Blue Nile State, Sudan

August 3, 2020 - 15:43 -- NOT Open Access
Author(s): 
Omer SA, Adam I, Noureldien A, Elhaj H, Guerrero-Latorre L, Silgado A, Sulleiro E, Molina I
Reference: 
J Trop Pediatr. 2020 Aug 1;66(4):428-434

Diagnosis of congenital malaria is complicated by the low density of the parasite circulating in the cord blood and/or the peripheral blood of the newborns. Molecular techniques are significantly more sensitive than blood smears in detecting low-level parasitemia. This study investigated the prevalence of congenital malaria by the use of the real-time polymerase chain reaction (real-time PCR) in 102 babies born to mothers with microscopically confirmed infected placenta from Blue Nile state, Sudan.

NOT Open Access | Congenital Malaria in Newborns Delivered to Mothers with Malaria-Infected Placenta in Blue Nile State, Sudan

January 24, 2020 - 14:57 -- NOT Open Access
Author(s): 
Omer SA, Adam I, Noureldien A, Elhaj H, Guerrero-Latorre L, Silgado A, Sulleiro E, Molina I
Reference: 
Journal of Tropical Pediatrics, fmz083

Diagnosis of congenital malaria is complicated by the low density of the parasite circulating in the cord blood and/or the peripheral blood of the newborns. Molecular techniques are significantly more sensitive than blood smears in detecting low-level parasitemia. This study investigated the prevalence of congenital malaria by the use of the real-time polymerase chain reaction (real-time PCR) in 102 babies born to mothers with microscopically confirmed infected placenta from Blue Nile state, Sudan.

Droughts, Dictators and the Immunity Trap in Sudan

December 1, 2014 - 18:20 -- William Jobin
Tags: 

My field experience in fighting malaria in Africa started with five years in central Sudan where I helped organize the Blue Nile Health Project in 1979, aimed at protecting 2 million people in the million acre Gezira Irrigation System. I benefited a great deal from the malaria experience of my Sudanese colleagues, as well as from the Iranians and others in the WHO Regional Office for the Eastern Mediterranean. I also benefited from the support of WHO Geneva, and from Letitia Obeng in UNEP.

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