Plasmodium falciparum resistance to chloroquine (CQ) and sulfadoxine-pyrimethamine (SP) has historically posed a major threat to malaria control throughout the world. The country of Angola officially replaced CQ with artemisinin-based combination therapy (ACT) as a first-line treatment in 2006, but malaria cases and deaths have recently been rising. Many classic resistance mutations are relevant for the efficacy of currently available drugs, making it important to continue monitoring their frequency in Angola.
No abstract available
Biennial therapeutic efficacy monitoring is a crucial activity for ensuring efficacy of currently used artemisinin-based combination therapy in Angola.
Malaria is one of the main causes of death in Angola, particularly among children under 5 years of age. An essential means to improve the situation is with strong malaria case management; this includes diagnosing suspected patients with a confirmatory test, either with a rapid diagnostic test (RDT) or microscopy, prompt and correct treatment with artemisinin-based combination therapy (ACT), and proper case registration (track). In 2011, the United States President’s Malaria Initiative (PMI) launched a country-wide programme to improve malaria case management through the provision of regular training and supervision at different levels of health care provision. An evaluation of malaria testing, treatment and registration practices in eight provinces, and at health facilities of various capacities, across Angola was conducted to assess progress of the national programme implementation.
DROUGHT AND MALARIA IN ANGOLA
Drought in southern Angola 2000 to 2006
When I was asked by the US Agency for International Development to go to Angola in 2005 to start the Presidential Malaria Initiative (PMI), I was told to begin spraying interiors of homes in the southern provinces of Huila and Kunene as soon as possible. I think they picked me because Portuguese is one of my favorite languages, and I had worked on malaria control in Sudan for 5 years, besides being with CDC in Puerto Rico when the island was finally declared malaria-free.