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A five-year trend analysis of malaria surveillance data in selected zones of Amhara region, Northwest Ethiopia

July 30, 2020 - 13:26 -- Open Access
Lankir D, Solomon S, Gize A
BMC Public Health. 2020 Jul 28; 20(1):1175

Trend analysis of malaria surveillance data is essential to inform stakeholders on progress towards malaria control. From the total 387,096 cases of malaria reported in Amhara region in 2017, 167,079 (43.2%) cases were in Central, North and West Gondar zones. From this total figure of zones, 15,445 (9.2%) were ≤ 5 years which contributes 4% of cases in the region. So, the purpose of this study was to analyze trends of malaria parasite in Selected Zones of Amhara Region, Northwest Ethiopia.

Therapeutic efficacy of artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Chewaka District, Ethiopia

July 14, 2020 - 09:17 -- Open Access
Abdulhakim Abamecha, Daniel Yilma, Wondimagegn Addisu, Hassan El-Abid, Achim Ibenthal, Harald Noedl, Delenasaw Yewhalaw, Mohieddine Moumni and Alemseged Abdissa
Malaria Journal 2020 19:240, 10 July 2020

The efficacy of artemether-lumefantrine (AL) for treatment of uncomplicated Plasmodium falciparum malaria in south-western Ethiopia is poorly documented. Regular monitoring of drug efficacy is an important tool for supporting national treatment policies and practice. This study investigated the therapeutic efficacy of AL for the treatment of P. falciparum malaria in Ethiopia.

School-based social and behavior change communication (SBCC) advances community exposure to malaria messages, acceptance, and preventive practices in Ethiopia: A pre-posttest study

June 29, 2020 - 16:14 -- Open Access
Kebede Y, Abebe L, Alemayehu G, Sudhakar M, Birhanu Z
PLoS One. 2020 Jun 25; 15(6):e0235189

Ethiopia has shown incredible success in malaria morbidity, mortality, and control. Community empowerment is a milestone to meet the ambitious plans of eliminating malaria by 2030.

Comprehensive competency assessment of malaria microscopists and laboratory diagnostic service capacity in districts stratified for malaria elimination in Ethiopia

June 29, 2020 - 16:12 -- Open Access
Nega D, Abebe A, Abera A, Gidey B, G/Tsadik A, Tasew G
PLoS One. 2020 Jun 25; 15(6):e0235151

Federal Ministry of Health (FMoH) Ethiopia achieved significant declines in malaria mortality and incidence and has recently launched malaria elimination in selected low transmission settings. Successful malaria elimination calls for rapid and accurate diagnosis of cases so that the patients can promptly be treated before the occurrence of transmission. Therefore, this study assessed the competency of malaria microscopists using panal slides, and laboratory service availability and readiness in terms of supplies and equipments in malaria elimination targeted districts in Ethiopia.

Exploring the impact of cattle on human exposure to malaria mosquitoes in the Arba Minch area district of southwest Ethiopia

June 26, 2020 - 15:18 -- Open Access
Zeru MA, Shibru S, Massebo F
Parasit Vectors. 2020 Jun 22;13(1):322

The success of indoor interventions that target mosquitoes for malaria control is partially dependent on early evening and outdoor biting behaviours of mosquito vectors. In southwest Ethiopia, people and cattle live in proximity, which calls to investigate whether the presence of cattle increase or decrease bites from malaria mosquito vectors. This study assessed both host-seeking and overnight activity of malaria mosquito vectors given the presence or absence of cattle in Chano Mille village, Arba Minch district, Ethiopia.

Disseminating clinical study results to trial participants in Ethiopia: insights and lessons learned

June 9, 2020 - 16:13 -- Open Access
Tamiru S. Degaga, Sophie Weston, Kamala Thriemer, et al.
Malaria Journal 2020 19:205, 8 June 2020

International regulatory authorities and funders require that research be disseminated promptly and appropriately to all involved stakeholders. However, following completion of clinical trials participants often either do not receive any feedback or materials provided are not appropriate for the context.

Genetic diversity and genotype multiplicity of Plasmodium falciparum infection in patients with uncomplicated malaria in Chewaka district, Ethiopia

June 9, 2020 - 16:07 -- Open Access
Abdulhakim Abamecha, Hassan El-Abid, Alemseged Abdissa, et al.
Malaria Journal 2020 19:203, 8 June 2020

Genetic diversity in Plasmodium falciparum poses a major threat to malaria control and elimination interventions. Characterization of the genetic diversity of P. falciparum strains can be used to assess intensity of parasite transmission and identify potential deficiencies in malaria control programmes, which provides vital information to evaluating malaria elimination efforts. This study investigated the P. falciparum genetic diversity and genotype multiplicity of infection in parasite isolates from cases with uncomplicated P. falciparum malaria in Southwest Ethiopia.

Performance of malaria microscopy external quality assessment and networking among health facilities in west Amhara region, Ethiopia

May 21, 2020 - 06:35 -- Open Access
Tegegne B, Ejigu K, Alemu G, Fetene Y, Endaylalu K, Melese M
BMC Infect Dis. 2020 May 19; 20(1):355

Microscopic examination of peripheral blood smear produces reliable results both about the malaria infection status and level of parasitemia. However, test results are affected by skill of the laboratory personnel, workload, condition of microscopes and quality of laboratory supplies. Therefore, continuous monitoring of the performance of laboratories is of pivotal importance in order to make timely correction.

NOT Open Access | Case Report: Primaquine Failure for Radical Cure of Plasmodium vivax Malaria in Gambella, Ethiopia

May 13, 2020 - 14:45 -- NOT Open Access
Teklehaimanot A, Teklehaimanot H, Girmay A, Woyessa A
Am J Trop Med Hyg. 2020 May 11

Failures of primaquine for the treatment of relapsed Plasmodium vivax malaria is a serious challenge to malaria elimination in Ethiopia, where P. vivax accounts for up to 40% of malaria infections. We report here occurrence of a total of 15 episodes of primaquine treatment failure for radical cure in three historical P. vivax malaria patients from Gambella, Ethiopia, during 8–16 months of follow-up in 1985–1987.

Insecticide resistance in Anopheles stephensi in Somali Region, eastern Ethiopia

May 12, 2020 - 16:42 -- Open Access
Solomon Yared, Araya Gebressielasie, Lambodhar Damodaran, Victoria Bonnell, Karen Lopez, Daniel Janies and Tamar E. Carter
Malaria Journal 2020 19:180, 12 May 2020

The movement of malaria vectors into new areas is a growing concern in the efforts to control malaria. The recent report of Anopheles stephensi in eastern Ethiopia has raised the necessity to understand the insecticide resistance status of the vector in the region to better inform vector-based interventions. The aim of this study was to evaluate insecticide resistance in An. stephensi in eastern Ethiopia using two approaches: (1) World Health Organization (WHO) bioassay tests in An. stephensi; and (2) genetic analysis of insecticide resistance genes in An. stephensi in eastern Ethiopia.


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