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ethiopia

In vivo efficacy of anti-malarial drugs against clinical Plasmodium vivax malaria in Ethiopia: a systematic review and meta-analysis

January 12, 2022 - 23:09 -- Open Access
Author(s): 
Tsige Ketema, Ketema Bacha, Kefelegn Getahun and Quique Bassat
Reference: 
Malaria Journal 2021 20:483, 24 December 2021

Ethiopia is one of the few countries in Africa where Plasmodium vivax commonly co-exists with Plasmodium falciparum, and which accounts for ~ 40% of the total number of malaria infections in the country. Regardless of the growing evidence over many decades of decreasing sensitivity of this parasite to different anti-malarial drugs, there has been no comprehensive attempt made to systematically review and meta-analyse the efficacy of different anti-malarial drugs against P. vivax in the country. However, outlining the efficacy of available anti-malarial drugs against this parasite is essential to guide recommendations for the optimal therapeutic strategy to use in clinical practice. The aim of this study was to synthesize evidence on the efficacy of anti-malarial drugs against clinical P. vivax malaria in Ethiopia.

The effect of long-lasting insecticidal nets (LLINs) physical integrity on utilization

January 5, 2022 - 23:04 -- Open Access
Author(s): 
Honelgn Nahusenay Hiruy, Ayele Zewde, Joseph Keating, et al.
Reference: 
Malaria Journal 2021 20:468, 18 December 2021

In Ethiopia, despite improvements in coverage and access, utilization of long-lasting insecticidal nets (LLINs) remains a challenge. Different household-level factors have been identified as associated with LLIN use. However, the contribution of LLIN physical integrity to their utilization is not well investigated and documented. This study aimed to assess the association between the physical integrity of LLINs and their use.

Community knowledge, perceptions, and practices regarding malaria and its control in Jabi Tehnan district, Amhara Region, Northwest Ethiopia

December 28, 2021 - 21:04 -- Open Access
Author(s): 
Abebe Asale, Zewdu Abro, Bayu Enchalew, Alayu Teshager, Aklilu Belay, Menale Kassie and Clifford Maina Mutero
Reference: 
Malaria Journal 2021 20:459, 9 December 2021

Use of long-lasting insecticidal nets (LLINs), indoor residual spraying (IRS), community-based malaria education, prompt diagnosis and treatment are key programme components of malaria prevention and control in Ethiopia. However, the effectiveness of these interventions is often undermined by various challenges, including insecticide and drug resistance, the plasticity of malaria vectors feeding and biting behaviour, and certain household factors that lead to misuse and poor utilization of LLINs. The primary objective of this study was to document households’ perceptions towards malaria and assess the prevalence of the disease and the constraints related to the ongoing interventions in Ethiopia (LLINs, IRS, community mobilization house screening).

Acceptability of peer learning and education approach on malaria prevention (PLEA-malaria) through primary schools communities in rural Ethiopia: peer educators’ perspectives

November 23, 2021 - 09:22 -- Open Access
Author(s): 
Fira Abamecha, Alemayehu Deressa, Morankar Sudhakar, Lakew Abebe, Yohannes Kebede, Dejene Tilahun, Firanbon Teshome and Zewdie Birhanu
Reference: 
Malaria Journal 2021 20:437, 15 November 2021

Evidence on peer educators’ experiences of implementing the school-based educational interventions on malaria prevention would be used as inputs for malaria eliminating efforts. This study explored the acceptability of the school-based peer-learning and education approach on malaria prevention (PLEA-malaria) among peer educators in Ethiopia.

Practices of anti-malaria pharmaceuticals inventory control system and associated challenges in public health facilities of Oromiya special zone, Amhara region, Ethiopia

November 10, 2021 - 20:54 -- Open Access
Author(s): 
Mengesha HY, Gebrehiwot GM, Workneh BD, Kahissay MH
Reference: 
BMC Public Health. 2021 Nov 6;21(1):2026

Anti-malaria pharmaceuticals inventory control system helps to maintain an appropriate stock level using logistics management information system records and reports. Antimalaria pharmaceuticals are highly influenced by seasonality and demand variation. Thus, to compensate the seasonality, resupply quantities should be adjusted by multiplying the historical consumption with the Look-ahead seasonality indexes (LSI) to minimize stock-outs during the peak transmission season and overstocks (possible expiries) during off-peak seasons The purpose of this study was to assess anti-malaria pharmaceuticals inventory control practice and associated challenges in public health facilities of the Oromiya special zone, Amhara region, Ethiopia.

Baseline malaria prevalence at the targeted pre-elimination districts in Ethiopia

November 4, 2021 - 12:58 -- Open Access
Author(s): 
Nega D, Abera A, Abate E, et al.
Reference: 
BMC Public Health. 2021 Nov 3;21(1):1996

Encouraged by the previous success in malaria control and prevention strategies, the Ethiopian ministry of health launched malaria elimination with a stepwise approach by primarily targeting the low-transmission Districts and their adjacent areas/zones in order to shrink the country’s malaria map progressively. Hence, this community survey was conducted to establish baseline malaria information at the preliminary phase of elimination at targeted settings.

Comorbidity of Geo-Helminthes among Malaria Outpatients of the Health Facilities in Ethiopia: Systematic Review and Meta-Analysis

October 30, 2021 - 12:56 -- Open Access
Author(s): 
Boltena MT, El-Khatib Z, Sahlemichael Kebede A, Asamoah BO, Tadesse Boltena A, Yeshambaw M, Biru M
Reference: 
Int J Environ Res Public Health. 2021 Jan 20;18(3):862

Coinfection of malaria and intestinal helminths affects one third of the global population, largely among communities with severe poverty. The spread of these parasitic infections overlays in several epidemiological locations and the host shows different outcomes. This systematic review and meta-analysis determine the pooled prevalence of malaria and intestinal helminthiases coinfections among malaria suspected patients in Ethiopia.

Genetic variation of Plasmodium falciparum histidine-rich protein 2 and 3 in Assosa zone, Ethiopia: its impact on the performance of malaria rapid diagnostic tests

October 23, 2021 - 18:09 -- Open Access
Author(s): 
Gezahegn Solomon Alemayehu, Alebachew Messele, Kayla Blackburn, Karen Lopez, Eugenia Lo, Daniel Janies and Lemu Golassa
Reference: 
Malaria Journal 2021 20:394, 9 October 2021

Rapid diagnostic tests (RDT) are commonly used for the diagnosis of malaria caused by Plasmodium falciparum. However, false negative results of RDT caused by genetic variation of P. falciparum histidine-rich protein 2 and 3 genes (pfhrp2/3) threaten existing malaria case management and control efforts. The main objective of this study was to investigate the genetic variations of the pfhrp2/3 genes.

The effect of irrigation on malaria vector bionomics and transmission intensity in western Ethiopia

October 16, 2021 - 13:07 -- Open Access
Author(s): 
Haileselassie W, Zemene E, Lee MC, Zhong D, Zhou G, Taye B, Dagne A, Deressa W, Kazura JW, Yan G, Yewhalaw D
Reference: 
Parasit Vectors. 2021 Oct 7;14(1):516

Irrigation schemes may result in subsequent changes in malaria disease dynamics. Understanding the mechanisms and effects of irrigation on malaria vector bionomics and transmission intensity is essential to develop new or alternative surveillance and control strategies to reduce or control malaria risk. This study was designed to assess the effect of rice irrigation on malaria vector bionomics and transmission intensity in the Gambella Region, Ethiopia.

Prevalence and associated factors of malaria in children under the age of five years in Wogera district, northwest Ethiopia: A cross-sectional study

October 16, 2021 - 13:00 -- Open Access
Author(s): 
Tsegaye AT, Ayele A, Birhanu S
Reference: 
PLoS One. 2021 Oct 11;16(10):e0257944

Malaria is a major public health problem in sub-Saharan Africa, and children are especially vulnerable. In 2019, an estimated 409,000 people died of malaria, most (274,000) were young children and 94% of the cases and deaths were in Africa. Prior studies in Ethiopia focused on the adult population and high transmission areas. Hence, this study aimed to determine the prevalence and associated factors of malaria in children under five years in low transmission areas.

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