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Presence of additional Plasmodium vivax malaria in Duffy negative individuals from Southwestern Nigeria

June 30, 2020 - 14:18 -- Open Access
Mary Aigbiremo Oboh, Upasana Shyamsunder Singh, Daouda Ndiaye, Aida Sadikh Badiane, Nazia Anwar Ali, Praveen Kumar Bharti and Aparup Das
Malaria Journal 2020 19:229, 26 June 2020

Malaria in sub-Saharan Africa (sSA) is thought to be mostly caused by Plasmodium falciparum. Recently, growing reports of cases due to Plasmodium ovale, Plasmodium malariae, and Plasmodium vivax have been increasingly observed to play a role in malaria epidemiology in sSA. This in fact is due to the usage of very sensitive diagnostic tools (e.g. PCR), which have highlighted the underestimation of non-falciparum malaria in this sub-region. Plasmodium vivax was historically thought to be absent in sSA due to the high prevalence of the Duffy negativity in individuals residing in this sub-continent. Recent studies reporting detection of vivax malaria in Duffy-negative individuals from Mali, Mauritania, Cameroon challenge this notion.

Haematological Parameters and Spleen Rate of Asymptomatic and Malaria Negative Children in Edo South District, Nigeria

June 29, 2020 - 16:25 -- Open Access
Nwaneri D, Oladipo O, Ifebi E, Oviawe O, Asemota O, Ogboghodo B, Israel-Aina Y, Sadoh A
Ann Glob Health. 2020 Jun 17; 86(1):62

Malaria is commonly associated with alteration in haematologic cells of infected individuals in both the acute uncomplicated and severe phases. Whether this alteration occurs in the asymptomatic phase of the disease is still being investigated.

NOT Open Access | Species Composition of Anopheles (Diptera: Culicidae) in Selected Forested Tourist Areas of Nigeria Endemic for Malaria

June 23, 2020 - 15:22 -- NOT Open Access
Oduwole OA, Oringanje CM, Oduola AO, Nwachuku NS, Meremikwu MM, Alaribe AAA
J Med Entomol. 2020 Jun 19:tjaa110

The study was carried out to determine relative abundance, species diversity, of Anopheles species (Diptera: Culicidae) in selected forested areas in Cross River State, Nigeria and the prevalence of malaria infection in the specimens. Mosquitoes were collected using pyrethrum spray catch and Centre for Disease Control light traps modified with yeast and sugar to generate carbon dioxide (CO2) and identified using morphological identification keys. We used a multiplex polymerase chain reaction followed by restriction fragment length polymorphism (PCR-RFLP) to simultaneously distinguish sibling species of the An. gambiae s.l, including separation of An. gambiae s.s. and An. coluzzii (Diptera: Culicidae).

Identification of Mutations in Antimalarial Resistance Gene Kelch13 from plasmodium falciparum Isolates in Kano, Nigeria

June 2, 2020 - 09:26 -- Open Access
Abubakar UF, Adam R, Mukhtar MM, Muhammad A, Yahuza AA, Ibrahim SS
Trop Med Infect Dis. 2020 May 27; 5 (2):E85

Malaria control relies on first-line treatments that use artemisinin-combination therapies (ACT). Unfortunately, mutations in the plasmodium falciparum kelch13 gene result in delayed parasite clearance. Research on what is causing ACT failure is non-existent in northwestern Nigeria. Thus, the presence of mutations in kelch13 in P. falciparum isolates from Kano, Nigeria was investigated in this study.

Statistical Modelling of the Effects of Weather Factors on Malaria Occurrence in Abuja, Nigeria

May 21, 2020 - 06:31 -- Open Access
Segun OE, Shohaimi S, Nallapan M, Lamidi-Sarumoh AA, Salari N
Int J Environ Res Public Health. 2020 May 16;17(10):E3474

Despite the increase in malaria control and elimination efforts, weather patterns and ecological factors continue to serve as important drivers of malaria transmission dynamics. This study examined the statistical relationship between weather variables and malaria incidence in Abuja, Nigeria.

A validation of the Malaria Atlas Project maps and development of a new map of malaria transmission in Sokoto, Nigeria: a cross-sectional study using geographic information systems

April 13, 2020 - 13:53 -- Open Access
Usman Nasir Nakakana, Ismaila Ahmed Mohammed, B. O. Onankpa, Ridwan M. Jega and Nma Muhammad Jiya
Malaria Journal 2020 19:149, 8 April 2020

Malaria remains a major cause of morbidity and mortality among children in Africa. There is inadequate information regarding malaria transmission-intensity in some of the worst-affected parts of sub-Saharan Africa (SSA). The Malaria Atlas Project (MAP) was developed in 2006, to project estimates of malaria transmission intensity where this data is not available, based on the vector behaviour for malaria. Data from malariometric studies globally were obtained and modelled to provide prevalence estimates. The sensitivity of these maps, however, reduces with unavailability of data. This necessitates a validation of these maps locally, and investigation into alternative methods of predicting prevalence to guide malaria control interventions and improve their efficiency and effectiveness. This study was conducted to compare the true estimates in Sokoto, Nigeria, with the MAP projections for north-western Nigeria, and it proposes an alternative way of mapping malaria intensity in Nigeria and beyond.

Individual and contextual correlates of mosquito net use among women in Nigeria

April 10, 2020 - 17:10 -- Open Access
Sulaimon T. Adedokun and Olalekan A. Uthman
Malaria Journal 2020 19:138, 7 April 2020

Malaria has been described as an urgent public health priority with almost half of the world’s population being at risk. Use of insecticide-treated nets is considered one of the effective ways of preventing malaria. Nigeria, which is ranked among the five countries that are responsible for almost half of the global malaria cases, has less than half of its women population using mosquito nets. This study examined the effects of individual and contextual factors on the use of mosquito nets among women of reproductive age in Nigeria.

NOT Open Access | Regional variation and demographic factors associated with knowledge of malaria risk and prevention strategies among pregnant women in Nigeria

April 6, 2020 - 08:41 -- NOT Open Access
Iyanda AE, Osayomi T, Boakye KA, Lu Y
Women & Health, Volume 60, 2020 - Issue 4

Pregnant women and children are the most vulnerable populations for malaria infection. Yet, knowledge of risk, and preventive measures are poor among this population. Using the 2015 Nigeria Malaria Indicator Survey, we applied logit link function to estimate the associations of wealth status, educational attainment, and region of residence with malaria risk knowledge and prevention strategies (using a treated mosquito net and malaria drugs) among 739 Nigerian pregnant women aged 15–49 years.

Monitoring the physical and insecticidal durability of the long-lasting insecticidal net DawaPlus® 2.0 in three States in Nigeria

March 31, 2020 - 15:20 -- Open Access
Emmanuel Obi, Festus Okoh, Albert Kilian, et al.
Malaria Journal 2020 19:124, 30 March 2020

Following guidance from the US President’s Malaria Initiative, durability monitoring of DawaPlus® 2.0 brand of long-lasting insecticidal net (LLIN) distributed during the 2015/16 mass campaign was set up in three ecologically different states: Zamfara, Ebonyi and Oyo.

The fidelity of implementation of recommended care for children with malaria by community health workers in Nigeria

March 10, 2020 - 16:11 -- Open Access
Adeoti O, Spiegelman D, Afonne C, Falade CO, Jegede AS, Oshiname FO, Gomes M, Ajayi IO
Implement Sci. 2020 Mar 4;15(1):13

In the context of task shifting, a promoted approach to healthcare delivery in resource-poor settings, trained community health workers (CHWs) have been shown to be effective in delivering quality care of malaria for febrile under-5 children. While their effectiveness has been documented, the fidelity of implementation (FOI) has not been adequately studied. By understanding and measuring whether an intervention has been performed with fidelity, researchers and practitioners gain a better understanding of how and why an intervention works, and the extent to which outcomes can be improved. The objective of this study was to assess the FOI of a recommended protocol for malaria care by CHWs in a resource-poor setting in Nigeria.


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