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What do malaria program officers want to learn? A survey of perspectives on a proposed malaria short course in Nigeria

October 2, 2021 - 13:15 -- Open Access
Ajumobi O, Afolabi RF, Adewole A, Balogun MS, Nguku P, Ajayi IO
PLoS One. 2021 Sep 29;16(9):e0257890

In disease control, the program officers are vital to the successful implementation of control strategies. However, poor knowledge of the disease and its control, staff attrition, and lack of intentional training for new staff can lead to under-performance and ineffectiveness of interventions. Thus, the Nigeria Field Epidemiology and Laboratory Training Program, in collaboration with National Malaria Elimination Program, planned a malaria short course (MSC) to strengthen the capacity of current program managers and incoming staff. To guide the development of the curriculum for the MSC, we conducted a needs assessment survey to ascertain the perceived usefulness of the MSC, the priority rating of MSC thematic domains and associated factors.

Knowledge, attitude, and practice of the National Guidelines for Diagnosis and Treatment of Malaria among medical doctors in Ebonyi state, Nigeria: A cross-sectional survey

September 25, 2021 - 11:57 -- Open Access
Omale UI
PLoS One. 2021 Sep 20;16(9):e0257600

The Guidelines for Diagnosis and Treatment of Malaria are meant to guide medical practitioners to enhance optimal management of patients suspected of having malaria which is vital to malarial control and elimination. Medical doctors have the main responsibility for treating patients with malaria so there was need to evaluate the extent to which the medical doctors in Ebonyi state, Nigeria, knew, viewed, and practiced the 2015 National Guidelines for Diagnosis and Treatment of Malaria.

Rural-urban dimensions of the perception of malaria severity and practice of malaria preventive measures: insight from the 2018 Nigeria Demographic and Health Survey

September 25, 2021 - 11:43 -- Open Access
Duodu PA, Dzomeku VM, Emerole CO, Agbadi P, Arthur-Holmes F, Nutor JJ
J Biosoc Sci. 2021 Sep 17:1-18

Morbidities and mortalities caused by malaria are still a serious issue in Nigeria, with the country accounting for 25% of malaria morbidities and 24% of malaria mortalities globally in 2018. Treated bed nets reduce the incidence of malaria, but not all Nigerians use them. This study aimed to examine the factors associated with treated bed net usage, including perceived severity of malaria, and the rural-urban differences in the relationship between socio-demographic factors and use of treated bed nets in Nigeria. The analytic sample size comprised 40,693 women aged 15-49 years.

NOT Open Access | Towards malaria control in Nigeria: implications of the malaria parasite rate and spleen rate among children living in a rural community in southwest Nigeria

September 1, 2021 - 16:19 -- NOT Open Access
Fatunla OAT, Olatunya OS, Ogundare EO, Fatunla TO, Oluwayemi IO, Oluwadiya KS, Oyelami OA
Trans R Soc Trop Med Hyg. 2021 Aug 30:trab131

The World Health Organization prioritizes malaria surveillance for accurate tracking of progress of intervention programmes. The malaria parasite rate (PR) and spleen rate (SR) are economical surveillance tools. There has been a global decline in the burden of malaria over the last decade, but most African countries, like Nigeria, have a slow rate of decline. There is a need for adequate malaria surveillance to guide malaria control strategies and policymaking.

NOT Open Access | Mutations in Pfcrt and Pfmdr1 genes of Plasmodium falciparum isolates from two sites in Northcentral and Southwest Nigeria

August 25, 2021 - 16:56 -- NOT Open Access
Agomo CO, Mishra N, Olukosi YA, Gupta R, Kamlesh K, Aina OO, Awolola ST
Infect Genet Evol. 2021 Aug 19:105042

The ability of malaria parasites to develop resistance to antimalarial drugs has made it necessary to continuously survey malaria parasite populations for resistance markers. Mutations in specific malaria parasite genes confer resistance to antimalarial drugs. The study compared mutations in Pfcrt and Pfmdr1 genes of P. falciparum from two ecologically different areas of Nigeria. Plasmodium falciparum dried blood spots collected from New Bussa (Northcentral Nigeria) and Ijede (Southwest Nigeria) were analysed by PCR-RFLP for Pfcrt, K76 T, Pfmdr1, N86Y and Y184F mutations.

Demand for malaria rapid diagnostic test, health care-seeking behaviour, and drug use among rural community members with fever or malaria-like illness in Ebonyi state, Nigeria: a cross-sectional household survey

August 25, 2021 - 16:43 -- Open Access
Omale UI, Oka OU, Okeke IM, Azuogu BN, Alo C, Madubueze UC, Eze II, Okeke KC, Utulu R, Akpan UE, Iloke CV, Nnubia AO, Ibemesi DO, Nnabu CR, Anene OC
BMC Health Serv Res. 2021 Aug 21;21(1):857

A good understanding of the demand for malaria rapid diagnostic test (MRDT), malaria health care-seeking behavior, and drug use among community members is crucial to malaria control efforts. The aim of this study was to assess the demand (use and/or request) for MRDT, health care-seeking behavior, and drug use, as well as associated factors, among rural community members (both children and adults) with fever or malaria-like illness in Ebonyi state, Nigeria.

NOT Open Access | High prevalence of plasmodium malariae and plasmodium ovale in co-infections with plasmodium falciparum in asymptomatic malaria parasite carriers in southwestern Nigeria

August 17, 2021 - 17:11 -- NOT Open Access
Abdulraheem MA, Ernest M, Ugwuanyi I, Abkallo HM, Nishikawa S, Adeleke M, Orimadegun AE, Culleton R
Int J Parasitol. 2021 Aug 11:S0020-7519(21)00239-3

Asymptomatic malaria parasite carriers do not seek anti-malarial treatment and may constitute a silent infectious reservoir. In order to assess the level of asymptomatic and symptomatic carriage amongst adolescents in a highly endemic area, and to identify the risk factors associated with such carriage, we conducted a cross-sectional survey of 1032 adolescents (ages 10-19 years) from eight schools located in Ibadan, southwestern Nigeria in 2016.

Does subsidizing the private for-profit sector benefit the poor? Evidence from national antimalarial subsidies in Nigeria and Uganda

July 28, 2021 - 12:49 -- Open Access
Tougher S, Hanson K, Goodman CA
Health Econ. 2021 Jul 22

Subsidising quality-assured artemisinin combination therapies (QAACTs) for distribution in the for-profit sector is a controversial strategy for improving access. The Affordable Medicines Facility-malaria (AMFm) was the largest initiative of this kind. We assessed the equity of AMFm in two ways using nationally representative household survey data on care seeking for children from Nigeria and Uganda.

Geopolitical zones differentials in intermittent preventive treatment in pregnancy (IPTp) and long lasting insecticidal nets (LLIN) utilization in Nigeria

July 20, 2021 - 13:16 -- Open Access
Chukwu C, Onuoha H, Okorafor KAK, Ojomo O, Mokuolu OA, Ekholuenetale M
PLoS One. 2021 Jul 16;16(7):e0254475

The coverage of long lasting insecticidal nets (LLIN) and intermittent preventive treatment of malaria in pregnancy (IPTp) uptake for the prevention of malaria commonly vary by geography. Many sub-Saharan Africa (SSA) countries, including Nigeria are adopting the use of LLIN and IPTp to fight malaria. Albeit, the coverage of these interventions to prevent malaria across geographical divisions have been understudied in many countries. In this study, we aimed to explore the differentials in LLIN and IPTp uptake across Nigerian geopolitical zones.

Oxygen systems and quality of care for children with pneumonia, malaria and diarrhoea: Analysis of a stepped-wedge trial in Nigeria

July 14, 2021 - 10:12 -- Open Access
Graham HR, Maher J, Bakare AA, Nguyen CD, Ayede AI, Oyewole OB, Gray A, Izadnegahdar R, Duke T, Falade AG
PLoS One. 2021 Jul 8;16(7):e0254229

To evaluate the effect of improved hospital oxygen systems on quality of care (QOC) for children with severe pneumonia, severe malaria, and diarrhoea with severe dehydration.


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