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review

NOT Open Access | Chalcone hybrids as privileged scaffolds in antimalarial drug discovery: A key review

March 19, 2020 - 09:07 -- NOT Open Access
Author(s): 
Qin HL, Zhang ZW, Lekkala R, Alsulami H, Rakesh KP
Reference: 
Eur J Med Chem. 2020 Mar 9; 193:112215

Malaria remains a serious worldwide health danger and massive economic trouble to disease-endemic nations. Presently, 250 million of malarial cases are expected worldwide. The emergence of fighting of the Plasmodium parasite against the first-line antimalarial drugs has fueled research attention in the way of designing new scaffolds as well as strategies to counter the drug resistance.

NOT Open Access | Dynamics of prevalence and distribution pattern of avian Plasmodium species and its vectors in diverse zoogeographical areas - A review

March 2, 2020 - 14:08 -- NOT Open Access
Author(s): 
Nourani L, Zakeri S, Djadid ND
Reference: 
Infection, Genetics and Evolution, 19 February 2020, 104244

Avian Plasmodium is of special interest to health care scientists and veterinarians due to the potency of causing avian malaria in non-adapted birds and their evolutionary phylogenetic relationship with human malaria species. This article aimed to provide a comprehensive list of the common avian Plasmodium parasites in the birds and mosquitoes, to specify the common Plasmodium species and lineages in the selected regions of West of Asia, East of Europe, and North of Africa/Middle East, and to determine the contribution of generalist and host-specific Plasmodium species and lineages.

Controlling mosquitoes with semiochemicals: a review

February 22, 2020 - 17:20 -- Open Access
Author(s): 
Wooding M, Naudé Y, Rohwer E, Bouwer M
Reference: 
Parasites Vectors 2020 Feb 17; 13(1):80

The use of semiochemicals in odour-based traps for surveillance and control of vector mosquitoes is deemed a new and viable component for integrated vector management programmes. Over 114 semiochemicals have been identified, yet implementation of these for management of infectious diseases such as malaria, dengue, chikungunya and Rift Valley fever is still a major challenge. The difficulties arise due to variation in how different mosquito species respond to not only single chemical compounds but also complex chemical blends.

Multiplicity of Asymptomatic Plasmodium falciparum Infections and Risk of Clinical Malaria: A Systematic Review and Pooled Analysis of Individual Participant Data

February 22, 2020 - 17:16 -- Open Access
Author(s): 
Eldh M, Hammar U, Arnot D, Beck HP, Garcia A, Liljander A, Mercereau-Puijalon O, Migot-Nabias F, Mueller I, Ntoumi F, Ross A, Smith T, Sondén K, Vafa Homann M, Yman V, Felger I, Färnert A
Reference: 
The Journal of Infectious Diseases, Volume 221, Issue 5, 1 March 2020, Pages 775–785

The malaria parasite Plasmodium falciparum holds an extensive genetic polymorphism. In this pooled analysis, we investigate how the multiplicity in asymptomatic P. falciparum infections—that is, the number of coinfecting clones—affects the subsequent risk of clinical malaria in populations living under different levels of transmission.

Pregnancy-specific malarial immunity and risk of malaria in pregnancy and adverse birth outcomes: a systematic review

January 24, 2020 - 14:45 -- Open Access
Author(s): 
Cutts JC, Agius PA, Zaw Lin, Powell R, Moore K, Draper B, Simpson JA, Fowkes FJI
Reference: 
BMC Med 18, 14 (2020)

In endemic areas, pregnant women are highly susceptible to Plasmodium falciparum malaria characterized by the accumulation of parasitized red blood cells (pRBC) in the placenta. In subsequent pregnancies, women develop protective immunity to pregnancy-associated malaria and this has been hypothesized to be due to the acquisition of antibodies to the parasite variant surface antigen VAR2CSA. In this systematic review we provide the first synthesis of the association between antibodies to pregnancy-specific P. falciparum antigens and pregnancy and birth outcomes.

Economic and Resource Use Associated With Management of Malaria in Children Aged <5 Years in Sub-Saharan Africa: A Systematic Literature Review

January 14, 2020 - 16:39 -- Open Access
Author(s): 
El-Houderi A, Constantin J, Castelnuovo E, Sauboin C
Reference: 
MDM Policy & Practice, 2019 Dec 21;4(2):2381468319893986.

Malaria is a major health, economic, and social burden in sub-Saharan Africa. The objective is to help understanding the economic impact of malaria and informing estimates of the potential economic impact of malaria prevention. To achieve this, we conducted a systematic review of published information on health system costs, health care resource use, and household costs for the management of malaria episodes in children aged <5 years in sub-Saharan Africa.

Book review: ‘The Encyclopedia of Medical and Veterinary Entomology’

November 14, 2013 - 22:25 -- Ingeborg van Schayk
Author(s): 
Bart GJ Knols
Reference: 
MWJ 2013, 4, 17

This article is a book review of 'The encyclopedia of medical and veterinary entomology', which is based on and adapted from the original text 'Medical and Veterinary Entomology'written by Prof. Douglas S. Kettle (the second edition, which was published in 1995).

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