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artemisinin-based combination therapy

Not Open Access | Imported malaria and artemisinin-based combination therapy failure in travellers returning to Belgium: A retrospective study

November 7, 2019 - 21:48 -- NOT Open Access
Author(s): 
Rovira-Vallbona E, Bottieau E, Guetens P, Verschueren J, Rebolledo J, Nulens E, Van der Hilst J, Clerinx J, Van Esbroeck M, Rosanas-Urgell A
Reference: 
Travel Med Infect Dis. 2019 Oct 30:101505 [Epub ahead of print]

BACKGROUND

Malaria (Plasmodium spp) remains a top cause of travel-associated morbidity among European residents. Here, we describe recent trends of imported malaria to Belgium and characterize the first cases of P.falciparum failure to artemisinin combination therapy (ACT).

METHODS

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Alternative methods for the Plasmodium falciparum artemisinin ring-stage survival assay with increased simplicity and parasite stage-specificity

February 22, 2016 - 17:19 -- Open Access
Author(s): 
Whitney A. Kite, Viviana A. Melendez-Muniz, Roberto R. Moraes Barros, Thomas E. Wellems and Juliana M. Sá
Reference: 
Malaria Journal 2016 15:94, 17 February 2016

Assessing P. falciparum ART sensitivity in vitro via RSA can be streamlined and accurately evaluated in the laboratory by filtration or sorbitol synchronization methods, thus increasing the accessibility of the assay to research groups.

Usefulness of Plasmodium falciparum-specific rapid diagnostic tests for assessment of parasite clearance and detection of recurrent infections after artemisinin-based combination therapy

October 18, 2013 - 15:57 -- Open Access
Author(s): 
Berit Aydin-Schmidt, Marycelina Mubi, Ulrika Morris, Max Petzold, Billy E Ngasala, Zul Premji, Anders Björkman, Andreas Mårtensson
Reference: 
Malaria Journal 2013, 12:349 (1 October 2013)
MalariaWorld

The results may have implications for the choice of RDT devices in similar transmission settings for improved malaria case management.

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