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plasmodium spp

Disruption of Apicoplast Biogenesis by Chemical Stabilization of an Imported Protein Evades the Delayed-Death Phenotype in Malaria Parasites

March 6, 2019 - 13:24 -- Open Access
Michael J. Boucher and Ellen Yeh
mSphere January/February 2019 4:e00710-18

Malaria parasites (Plasmodium spp.) contain a nonphotosynthetic plastid organelle called the apicoplast, which houses essential metabolic pathways and is required throughout the parasite life cycle.

Antagonistic effects of Plasmodium-helminth co-infections on malaria pathology in different population groups in Côte d’Ivoire

January 15, 2019 - 15:32 -- Open Access
Eveline Hürlimann, Clarisse A. Houngbedji, Richard B. Yapi, Prisca B. N’Dri, Kigbafori D. Silué, Mamadou Ouattara, Jürg Utzinger, Eliézer K. N’Goran, Giovanna Raso
PLoS Negl Trop Dis 13(1): e0007086

No exacerbation from co-infection with Plasmodium and helminths was observed, neither in participants aged 5–18 years nor in adults from the community-based studies.

Reassessment of asymptomatic carriers of Plasmodium spp. in an endemic area with a very low incidence of malaria in extra-Amazonian Brazil

November 14, 2017 - 15:46 -- Open Access
Filomena E. C. de Alencar, Rosely dos Santos Malafronte, Crispim Cerutti Jr., Lícia Natal Fernandes, Julyana Cerqueira Buery, Blima Fux, Helder Ricas Rezende and Angelica Espinosa Miranda
Malaria Journal 2017 16:452, 9 November 2017

The findings suggest that untreated dwellers from this extra-Amazonian region, who initially harbour malaria parasites, may become negative without ever developing apparent symptoms of the disease.

NOT Open Access | Variant surface antigens of Plasmodium falciparum and their roles in severe malaria

July 25, 2017 - 15:31 -- NOT Open Access
Mats Wahlgren, Suchi Goel & Reetesh R. Akhouri
Nature Reviews Microbiology 15, 479–491 (2017)

Proliferation and differentiation inside erythrocytes are important steps in the life cycle of Plasmodium spp.

Bioluminescence Method for In Vitro Screening of Plasmodium Transmission-Blocking Compounds

May 25, 2017 - 14:43 -- Open Access
Raquel Azevedo, Marija Markovic, Marta Machado, Blandine Franke-Fayard, António M. Mendes, and Miguel Prudêncio
Antimicrob. Agents Chemother. June 2017 vol. 61 no. 6 e02699-16

The sporogonic stage of the life cycle of Plasmodium spp., the causative agents of malaria, occurs inside the parasite's mosquito vector, where a process of fertilization, meiosis, and mitotic divisions culminates in the generation of large numbers of mammalian-infective sporozoites.

Exo-erythrocytic development of avian malaria and related haemosporidian parasites

March 9, 2017 - 15:44 -- Open Access
Gediminas Valkiūnas and Tatjana A. Iezhova
Malaria Journal 2017 16:101, 3 March 2017

Recent molecular studies combined with histological research show that avian haemosporidians are more virulent than formerly believed.

Prevalence of Plasmodium spp. in illegal gold miners in French Guiana in 2015: a hidden but critical malaria reservoir

June 13, 2016 - 16:21 -- Open Access
Maylis Douine, Lise Musset, Mathieu Nacher, et al.
Malaria Journal 2016 15:315, 9 June 2016

This significant malaria reservoir in a mobile and illegal population with difficult access to a health care system raises the threat of artemisinin resistance and puts the population of the Guiana Shield at risk of new transmission foci while countries of the region aim at malaria elimination.


A method to preserve low parasitaemia Plasmodium-infected avian blood for host and vector infectivity assays

March 15, 2016 - 18:53 -- Open Access
Jenny S. Carlson, Federico Giannitti, Gediminas Valkiūnas, Lisa A. Tell, Joy Snipes, Stan Wright and Anthony J. Cornel
Malaria Journal 2016 15:154, 11 March 2016

A simple method of collecting and preserving avian whole blood with malaria parasites of low parasitaemia (≤0.0005 %) was developed that remained viable for further experimental bird and mosquito infectivity assays.

Survey of Plasmodium in the golden-headed lion tamarin (Leontopithecus chrysomelas) living in urban Atlantic forest in Rio de Janeiro, Brazil

February 22, 2016 - 17:17 -- Open Access
Elizabeth Helen Aitken, Marina Galvão Bueno, Luana dos Santos Ortolan, José M. Alvaréz, Alcides Pissinatti, Maria Cecília Martins Kierulff, José Luiz Catão-Dias and Sabrina Epiphanio
Malaria Journal 2016 15:93, 17 February 2016

This study is the first to provide information on Plasmodium spp. infection in L. chrysomelas. Plasmodium spp.


Epigenetic Roulette in Blood Stream Plasmodium: Gambling on Sex

February 15, 2016 - 18:22 -- Open Access
Andrew P. Waters
PLoS Pathog 12(2): e1005353

The well-known and invidious pathology caused by malaria parasites (Plasmodium spp.) stems from the intraerythrocytic developmental cycle (IDC), which is the progressive invasion of erythrocytes by the merozoite form of the parasite followed by parasite growth, asexual replication, and lysis of the host cell liberating logarithmically greater numbers of infectious merozoites.


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