The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10434 malaria professionals are enjoying the free benefits of MalariaWorld today

merozoite

Immunogenicity analysis of conserved fragments in Plasmodium ovale species merozoite surface protein 4

March 31, 2020 - 15:25 -- Open Access
Author(s): 
Juliette Uwase, Ruilin Chu, Kokouvi Kassegne, Yao Lei, Feihu Shen, Haitian Fu, Yifan Sun, Yinghua Xuan, Jun Cao and Yang Cheng
Reference: 
Malaria Journal 2020 19:126, 30 March 2020

There is an urgent need for an effective vaccine to control and eradicate malaria, one of the most serious global infectious diseases. Plasmodium merozoite surface protein 4 (MSP4) has been listed as a blood-stage subunit vaccine candidate for malaria. Infection with Plasmodium ovale species including P. ovale wallikeri and P. ovale curtisi, is also a source of malaria burden in tropical regions where it is sometimes mixed with other Plasmodium species. However, little is known about P. ovale MSP4.

Genetic polymorphism of merozoite surface proteins 1 and 2 of Plasmodium falciparum in the China–Myanmar border region

November 26, 2019 - 13:26 -- Open Access
Author(s): 
Cang-Lin Zhang, Hong-Ning Zhou, Quan Liu and Ya-Ming Yang
Reference: 
Malaria Journal 2019 18: 367, 19 November 2019

Malaria is a major public health problem in the China–Myanmar border region. The genetic structure of malaria parasite may affect its transmission model and control strategies. The present study was to analyse genetic diversity of Plasmodium falciparum by merozoite surface proteins 1 and 2 (MSP1 and MSP2) and to determine the multiplicity of infection in clinical isolates in the China–Myanmar border region.

Medical Condition: 

Not Open Access | Host–parasite interactions that guide red blood cell invasion by malaria parasites

April 11, 2015 - 11:48 -- NOT Open Access
Author(s): 
Aditya S Paul, Elizabeth S Egan, Manoj T Duraisingh
Reference: 
Current Opinion in Hematology: May 2015 - Volume 22 - Issue 3 - p 220–226

Here, we review recent advances on RBC invasion by Plasmodium merozoites, focusing on specific molecular interactions between host and parasite.

Not Open Access | RALP1 is a rhoptry-neck erythrocyte-binding protein of Plasmodium falciparum merozoite and a potential blood-stage vaccine candidate antigen.

September 6, 2013 - 19:09 -- NOT Open Access
Author(s): 
Ito D, Hasegawa T, Tsuboi T, et al.
Reference: 
Infect Immun. 2013 Sep 3.
MalariaWorld

The findings that RALP1 possesses an erythrocyte binding epitope in the C-terminal region and that anti-RALP1 antibodies disrupt the tight junction formation, are evidences to suggest that RALP1 plays an important role during merozoite invasion into erythrocytes.

Subscribe to RSS - merozoite