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Treatment

Three unusual presentations of plasmodium vivax malaria

September 28, 2011 - 06:50 -- Kabogo Ndegwa
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Author(s): 
Satyendra Kumar Sonkar, Ravi Uniyal, and Gyanendra Kumar Sonkar
Reference: 
Trop Doct October 2011 vol. 41 no. 4 240-241

We present three cases of unusual and complicated malaria caused by Plasmodium vivax.

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Can lay community health workers be trained to use diagnostics to distinguish and treat malaria and pneumonia in children? Lessons from rural Uganda

September 21, 2011 - 07:10 -- Kabogo Ndegwa
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Author(s): 
D. Mukanga, R. Babirye, S. Peterson, G. W. Pariyo, G. Ojiambo, J. K. Tibenderana, P. Nsubuga and K. Kallander
Reference: 
Tropical Medicine & International Health, Volume 16, Issue 10, pages 1234–1242, October 2011

Community health workers can be trained to use RDTs and timers to assess and manage malaria and pneumonia in children.

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Do poor people use poor quality providers? Evidence from the treatment of presumptive malaria in Nigeria (pages 1087–1098)

August 11, 2011 - 07:24 -- Kabogo Ndegwa
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Author(s): 
Obinna Onwujekwe, Kara Hanson and Benjamin Uzochukwu
Reference: 
Tropical Medicine & International Health, Volume 16, Issue 9, pages 1087–1098, September 2011

Everybody used poor quality malaria treatment services but the poor people used providers with poor quality malaria treatment services more than others.

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Open Access | Accuracy of malaria rapid diagnostic tests in community studies and their impact on treatment of malaria in an area with declining malaria burden in north-eastern Tanzania

June 29, 2011 - 06:54 -- Kabogo Ndegwa
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Author(s): 
Ishengoma DS, Francis F, Mmbando BP, Lusingu JP, Magistrado P, Alifrangis M, Theander TG, Bygbjerg IC, Lemnge MM
Reference: 
Malaria Journal 2011, 10:176 (26 June 2011)

Although RDTs had low sensitivity and specificity, which varied widely depending on fever and parasite density, using RDTs reduced over-treatment with anti-malarials significantly.

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Plasmodium berghei proteome changes in response to SSJ-183 treatment

June 23, 2011 - 07:25 -- Kabogo Ndegwa
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Author(s): 
Jun Lu, Chika Arai, Abu Bakar Md, Masataka Ihara
Reference: 
Bioorganic & Medicinal Chemistry, Volume 19, Issue 13, 1 July 2011, Pages 4144-4147

The benzo[a]phenoxazine derivative, SSJ-183 has shown excellent anti-malarial efficacy and safety.

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Development, Evaluation, and Application of an In Silico Model for Antimalarial Drug Treatment and Failure

June 21, 2011 - 06:55 -- Kabogo Ndegwa
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Author(s): 
Katherine Winter and Ian M. Hastings
Reference: 
Antimicrobial Agents and Chemotherapy, July 2011,p. 3380-3392, Vol. 55, No. 7

Pharmacological mechanism-based modeling was refined and used to develop an in silico model of antimalarial drug treatment validated against clinical and field data.

Open Access | Community case management of malaria using ACT and RDT in two districts in Zambia: achieving high adherence to test results using Community Health Workers

June 13, 2011 - 07:22 -- Kabogo Ndegwa
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Author(s): 
Chanda P, Hamainza B, Moonga HB, Chalwe V, Pagnoni F
Reference: 
Malaria Journal 2011, 10:158 (9 June 2011)

CHWs are effective delivery points for prompt and effective malaria case management at community level.

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Open Access | Paracetamol versus placebo in treatment of non-severe malaria in children in Guinea-Bissau: a randomized controlled trial

June 2, 2011 - 07:20 -- Kabogo Ndegwa
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Author(s): 
Kofoed P, Ursing J, Rodrigues A, Rombo L
Reference: 
Malaria Journal 2011, 10:148 (1 June 2011)

Fewer children had early treatment failure and the mean temperature was slightly lower in the afternoon on day 0 in the paracetamol group.

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Open Access | The Impact of Retail-Sector Delivery of Artemether–Lumefantrine on Malaria Treatment of Children under Five in Kenya: A Cluster Randomized Controlled Trial

June 2, 2011 - 07:17 -- Kabogo Ndegwa
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Author(s): 
Beth P. Kangwana, Sarah V. Kedenge, Abdisalan M. Noor, Victor A. Alegana, Andrew J. Nyandigisi, Jayesh Pandit, Greg W. Fegan, James E. Todd, Simon Brooker, Robert W. Snow, Catherine A. Goodman
Reference: 
PLoS Med 8(5): e1000437

Subsidizing ACT in the retail sector can significantly increase ACT coverage for reported fevers in rural areas.

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Open Access | Community perceptions of malaria and vaccines in South Coast and Busia regions of Kenya

May 31, 2011 - 11:53 -- Kabogo Ndegwa
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Author(s): 
Ojakaa DI, Ofware P, Machira YW, Yamo E, Collymore Y, Ba-Nguz A, Vansadia P, Bingham A
Reference: 
Malaria Journal 2011, 10:147 (30 May 2011)

The study raises issues that should inform a communications strategy and guide policy decisions within Kenya on eventual malaria vaccine introduction.

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