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Treatment

Superbug: an emerging and quickly spreading threat to the race against malaria

February 17, 2017 - 09:46 -- Salomé Beaujouan

While the malaria death count in Cambodia dropped to just one case in 2016, a new threat to the race against the disease arises in south-eastern Asia: superbugs. A superbug is a drug-resistant, human-killing parasite that modern medicine struggles to combat.

Open Access | Costs analysis of the treatment of imported malaria

January 4, 2012 - 07:33 -- Kabogo Ndegwa
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Author(s): 
Svihrova V, Szilagyiova M, Novakova E, Svihra J, Hudeckova H
Reference: 
Malaria Journal 2012, 11:1 (2 January 2012)

MalariaWorldThe analysis confirmed statistically-significant differences between the direct and indirect costs of treatment with and without chemoprophylaxis for patients with imported malaria.

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Open Access | Cost-effectiveness of malaria microscopy and rapid diagnostic tests versus presumptive diagnosis: implications for malaria control in Uganda

December 21, 2011 - 10:01 -- Kabogo Ndegwa
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Author(s): 
Batwala V, Magnussen P, Hansen KS, Nuwaha F
Reference: 
Malaria Journal 2011, 10:372 (19 December 2011)

MalariaWorldRDT was cost effective in both low and high transmission settings.

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Plasmodium vivax treatments: what are we looking for?

October 26, 2011 - 14:08 -- Kabogo Ndegwa
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Author(s): 
Price, Ric N.; Douglas, Nicholas M.; Anstey, Nicholas M.; von Seidlein, Lorenz
Reference: 
C urrent Opinion in Infectious Diseases, December 2011 - Volume 24 - Issue 6 - p 578–585

MalariaWorldIn regions coendemic for P. vivax and P. falciparum, a unified treatment policy for malaria of any parasitological cause is likely to confer the greatest individual and public health benefit.

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Open Access | A thirteen-year analysis of Plasmodium falciparum populations reveals high conservation of the mutant pfcrt haplotype despite the withdrawal of chloroquine from national treatment guidelines in Gabon

October 19, 2011 - 07:26 -- Kabogo Ndegwa
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Author(s): 
Frank M, Lehners N, Mayengue PI, Gabor J, Dal-Bianco M, Kombila DU, Mombo Ngoma G, Supan C, Lell B, Ntoumi F, Grobusch MP, Dietz K, Kremsner PG
Reference: 
Malaria Journal 2011, 10:304 (17 October 2011)

MalariaWorldFour years after the withdrawal of CQ from national treatment guidelines the prevalence of the mutant pfcrt allele remains at 97%.

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Three unusual presentations of plasmodium vivax malaria

September 28, 2011 - 06:50 -- Kabogo Ndegwa
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Author(s): 
Satyendra Kumar Sonkar, Ravi Uniyal, and Gyanendra Kumar Sonkar
Reference: 
Trop Doct October 2011 vol. 41 no. 4 240-241

We present three cases of unusual and complicated malaria caused by Plasmodium vivax.

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Can lay community health workers be trained to use diagnostics to distinguish and treat malaria and pneumonia in children? Lessons from rural Uganda

September 21, 2011 - 07:10 -- Kabogo Ndegwa
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Author(s): 
D. Mukanga, R. Babirye, S. Peterson, G. W. Pariyo, G. Ojiambo, J. K. Tibenderana, P. Nsubuga and K. Kallander
Reference: 
Tropical Medicine & International Health, Volume 16, Issue 10, pages 1234–1242, October 2011

Community health workers can be trained to use RDTs and timers to assess and manage malaria and pneumonia in children.

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Do poor people use poor quality providers? Evidence from the treatment of presumptive malaria in Nigeria (pages 1087–1098)

August 11, 2011 - 07:24 -- Kabogo Ndegwa
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Author(s): 
Obinna Onwujekwe, Kara Hanson and Benjamin Uzochukwu
Reference: 
Tropical Medicine & International Health, Volume 16, Issue 9, pages 1087–1098, September 2011

Everybody used poor quality malaria treatment services but the poor people used providers with poor quality malaria treatment services more than others.

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Open Access | Accuracy of malaria rapid diagnostic tests in community studies and their impact on treatment of malaria in an area with declining malaria burden in north-eastern Tanzania

June 29, 2011 - 06:54 -- Kabogo Ndegwa
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Author(s): 
Ishengoma DS, Francis F, Mmbando BP, Lusingu JP, Magistrado P, Alifrangis M, Theander TG, Bygbjerg IC, Lemnge MM
Reference: 
Malaria Journal 2011, 10:176 (26 June 2011)

Although RDTs had low sensitivity and specificity, which varied widely depending on fever and parasite density, using RDTs reduced over-treatment with anti-malarials significantly.

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Plasmodium berghei proteome changes in response to SSJ-183 treatment

June 23, 2011 - 07:25 -- Kabogo Ndegwa
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Author(s): 
Jun Lu, Chika Arai, Abu Bakar Md, Masataka Ihara
Reference: 
Bioorganic & Medicinal Chemistry, Volume 19, Issue 13, 1 July 2011, Pages 4144-4147

The benzo[a]phenoxazine derivative, SSJ-183 has shown excellent anti-malarial efficacy and safety.

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