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Improving Pharmacokinetic-Pharmacodynamic Modeling to Investigate Anti-Infective Chemotherapy with Application to the Current Generation of Antimalarial Drugs

July 31, 2013 - 15:27 -- Open Access
Author(s): 
Katherine Kay, Ian M. Hastings
Reference: 
PLoS Comput Biol 9(7): e1003151
MalariaWorld

Mechanism-based pharmacokinetic-pharmacodynamic (PK/PD) modelling is the standard computational technique for simulating drug treatment of infectious diseases with the potential to enhance our understanding of drug treatment outcomes, drug deployment strategies, and dosing regimens.

Medical Treatment: 
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