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artemisinin combination therapies (ACTs

Improving Pharmacokinetic-Pharmacodynamic Modeling to Investigate Anti-Infective Chemotherapy with Application to the Current Generation of Antimalarial Drugs

July 31, 2013 - 15:27 -- Open Access
Katherine Kay, Ian M. Hastings
PLoS Comput Biol 9(7): e1003151

Mechanism-based pharmacokinetic-pharmacodynamic (PK/PD) modelling is the standard computational technique for simulating drug treatment of infectious diseases with the potential to enhance our understanding of drug treatment outcomes, drug deployment strategies, and dosing regimens.

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