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Not Open Access | Prevalence of mutations in the antifolates resistance-associated genes (dhfr and dhps) in Plasmodium vivax parasites from Eastern and Central Sudan

June 20, 2014 - 17:45 -- NOT Open Access
Sekineh Pirahmadi, Badawi Abdelbagi Talha, Bakri Y.M. Nour, Sedigheh Zakeri
Infection, Genetics and Evolution, Volume 26, August 2014, Pages 153-159

Therefore, the main objective of the present study was to provide data on the prevalence of molecular markers in two genes (pvdhfr and pvdhps) associated with SP resistance after nine years of AS + SP deployment among P. vivax parasites from Eastern and Central Sudan using PCR-RFLP.

A flow cytometric assay to quantify invasion of red blood cells by rodent Plasmodium parasites in vivo

April 7, 2014 - 17:17 -- Open Access
Lelliott PM, Lampkin S, McMorran BJ, Foote SJ, Burgio G
Malaria Journal 2014, 13 :100 (17 March 2014)

Assays for analysing parasite invasion in vitro have been developed, but no equivalent assays exist for in vivo studies. This article describes a novel flow cytometric in vivo parasite invasion assay.

Efficacy of a Plasmodium vivax malaria vaccine using ChAd63 and MVA expressing TRAP assessed with transgenic Plasmodium berghei parasites.

January 6, 2014 - 16:08 -- Open Access
Karolis Bauza, Tomas Malinauskas, Claudia Pfander, Burcu Anar, E. Yvonne Jones, Oliver Billker, Adrian V.S. Hill and Arturo Reyes-Sandoval
Infection and Immunity , volume 82, issue 1, January 2014

In addition, we report a novel way of assessing efficacy of new candidate vaccines against P. vivax using a fully infectious transgenic Plasmodium berghei parasite expressing P. vivax TRAP to allow studies of vaccine efficacy and protective mechanisms in rodents.

Not Open Access | Pharmacokinetics and in vivo chemosuppressive activity studies on cryptolepine hydrochloride and cryptolepine hydrochloride-loaded gelatine nanoformulation designed for parenteral administration for the treatment of malaria

July 18, 2013 - 05:22 -- NOT Open Access
N. Kuntworbe, M. Ofori, P. Addo, M. Tingle, R. Al-Kassas
Acta Tropica, Volume 127, Issue 3, September 2013, Pages 165-173

The main objective of this investigation was to establish the pharmacokinetics profile and in vivo chemosuppressive activities of cryptolepine hydrochloride-loaded gelatine nanoparticles (CHN) designed for parenteral administration for the treatment of malaria in comparison to the drug free in solution (CHS)

Stress and sex in malaria parasites. Why does commitment vary?

July 9, 2013 - 15:06 -- Open Access
Lucy M. Carter, Björn F.C. Kafsack, Manuel Llinás, Nicole Mideo, Laura C. Pollitt and Sarah E. Reece
Evolution, Medicine, and Public Health, Volume 2013, Issue 1 Pp. 135-147.

We examine why parasites adjust investment in gametocytes according to the impact of changing conditions on their in-host survival.


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