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basic reproductive number

GCE Special: Endectocides for controlling transmission of mosquito-borne diseases

May 27, 2013 - 19:40 -- Bart G.J. Knols
Author(s): 
Massamba Sylla, Kevin C. Kobylinski, Brian D. Foy
Reference: 
MWJ 2013, 4, 5

The aim of this GCE project was to develop a control method that targets the most important variables of vectorial capacity (VC) and the basic reproductive number (Ro) so malaria parasite transmission would be maximally impacted, but that did so by targeting mosquitoes through human blood meals. This would a) target all malaria vectors around a community, regardless of when and where they bite, and b) ensure that the effector molecules directly entered the midgut of mosquitoes rather than needing to be efficiently applied in the environment and then efficiently penetrate the vectors’ cuticle.

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