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anopheles sinensis

Genomic Variant Analyses in Pyrethroid Resistant and Susceptible Malaria Vector, Anopheles sinensis

May 20, 2020 - 10:29 -- Open Access
Author(s): 
Chang X, Zhong D, Wang X, Bonizzoni M, Li Y, Zhou G, Cui L, Wei X, Yan G
Reference: 
G3 (Bethesda). 2020 May 18:g3.401279.2020

Anopheles sinensis is a major malaria vector in Southeast Asia. Resistance to pyrethroid insecticides in this species has impeded malaria control in the region. Previous studies found that An. sinensis populations from Yunnan Province, China were highly resistant to deltamethrin and did not carry mutations in the voltage-gated sodium channel gene that cause knockdown resistance.

RDL mutations in Guangxi Anopheles sinensis populations along the China–Vietnam border: distribution frequency and evolutionary origin of A296S resistance allele

January 20, 2020 - 15:39 -- Open Access
Author(s): 
Nian Liu, Xiangyang Feng and Xinghui Qiu
Reference: 
Malaria Journal 2020 19:23, 15 January 2020

Malaria is a deadly vector-borne disease in tropical and subtropical regions. Although indigenous malaria has been eliminated in Guangxi of China, 473 confirmed cases were reported in the Northern region of neighbouring Vietnam in 2014.

The polymorphism and geographical distribution of knockdown resistance of adult Anopheles sinensis populations in eastern China

May 13, 2019 - 12:14 -- Open Access
Author(s): 
Wei-Long Tan, Chun-Xiao Li, Tong-Yan Zhao, et al.
Reference: 
Malaria Journal 2019 18:164, 7 May 2019

Anopheles sinensis is one of the major malaria vectors in China and other southeast Asian countries, including Vietnam, Cambodia, Thailand. Vector control is considered to be the critical measure for malaria control, while the increasing prevalence of insecticide resistance caused by long-term use of insecticides, especially pyrethroids, is threatening the successful control of An. sinensis. In order to understand the underlying resistance mechanisms involved and molecular basis, the principal malaria vector, An. sinensis from Jiangsu and Anhui provinces, Southeast China, was investigated.

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Modification of contact avoidance behaviour associated with pyrethroid resistance in Anopheles sinensis (Diptera: Culicidae)

April 14, 2019 - 17:06 -- Open Access
Author(s): 
Zhengbo He, Jing Zhang, Zongpan Shi, Jingang Liu, Jingjing Zhang, Zhentian Yan and Bin Chen
Reference: 
Malaria Journal 2019 18:131, 11 April 2019

The An. sinensis populations were highly resistant to deltamethrin and exhibited decreased avoidance behaviour.

An odorant receptor from Anopheles sinensis in China is sensitive to oviposition attractants

October 16, 2018 - 14:10 -- Open Access
Author(s): 
Hongmei Liu, Luhong Liu, Peng Cheng, Xiaodan Huang and Maoqing Gong
Reference: 
Malaria Journal 2018 17:348, 5 October 2018

AsinOrco was characterized as a new member of the Orco ortholog subfamily.

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Comparative physical genome mapping of malaria vectors Anopheles sinensis and Anopheles gambiae

June 6, 2017 - 15:49 -- Open Access
Author(s): 
Yun Wei, Biao Cheng, Ai Xia, et al.
Reference: 
Malaria Journal 2017 16:235, 5 June 2017

The physical map will facilitate detailed genomic analysis of An. sinensis and contribute to understanding of the patterns and mechanisms of large-scale genome rearrangements in anopheline mosquitoes.

Diversity and frequency of kdr mutations within Anopheles sinensis populations from Guangxi, China

August 23, 2016 - 16:34 -- Open Access
Author(s): 
Chan Yang, Xiangyang Feng, Zushi Huang, Mei Li and Xinghui Qiu
Reference: 
Malaria Journal 2016 15:411, 15 August 2016

Diverse haplotypes of AS-VGSC are distributed in Guangxi.

Landscape genetic structure and evolutionary genetics of insecticide resistance gene mutations in Anopheles sinensis

April 26, 2016 - 16:21 -- Open Access
Author(s): 
Chang X, Zhong D, Yan G, et al.
Reference: 
Parasites & Vectors 2016, 9 :228 (23 April 2016)

Despite the importance of kdr mutations in pyrethroid resistance, the evolutionary origin of the kdr mutations is unknown. This study aims to examine the evolutionary genetics of kdr mutations in relation to spatial population genetic structure of An. sinensis.

Distribution and frequency of G119S mutation in ace-1 gene within Anopheles sinensis populations from Guangxi, China

November 26, 2015 - 05:49 -- Open Access
Author(s): 
Xiangyang Feng, Chan Yang, Yichao Yang, Jun Li, Kangming Lin, Mei Li, Xinghui Qiu
Reference: 
Malaria Journal 2015, 14:470 (25 November 2015)

The G119S mutation has become fixed and is widespread in An. sinensis field populations in Guangxi, China.

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Historical survey of the kdr mutations in the populations of Anopheles sinensis in China in 1996-2014

March 23, 2015 - 12:06 -- Open Access
Author(s): 
Yan Wang, Wanqin Yu, Hua Shi, Zhenzhou Yang, Jiannong Xu, Yajun Ma
Reference: 
Malaria Journal 2015, 14:120 (20 March 2015)

The survey revealed that the kdr occurrence and accumulation in the An. sinensis populations were more frequent in central China than in the other regions, suggesting that the kdr mutations may contribute significantly to the pyrethroid resistance in the mosquitoes in central China.

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