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anemia

Atypical memory B-cells and autoantibodies correlate with anemia during Plasmodium vivax complicated infections

July 21, 2020 - 15:15 -- Open Access
Author(s): 
Rivera-Correa J, Yasnot-Acosta MF, Tovar NC, Velasco-Pareja MC, Easton A, Rodriguez A
Reference: 
PLoS Negl Trop Dis 14(7): e0008466

Malaria caused by Plasmodium vivax is a highly prevalent infection world-wide, that was previously considered mild, but complications such as anemia have been highly reported in the past years. In mice models of malaria, anti-phosphatidylserine (anti-PS) autoantibodies, produced by atypical B-cells, bind to uninfected erythrocytes and contribute to anemia. In human patients with P. falciparum malaria, the levels of anti-PS, atypical B-cells and anemia are strongly correlated to each other.

Prevalence and Correlates of Asymptomatic Malaria and Anemia on First Antenatal Care Visit among Pregnant Women in Southeast, Tanzania

May 6, 2020 - 15:54 -- Open Access
Author(s): 
Mlugu EM, Minzi O, Kamuhabwa AAR, Aklillu E
Reference: 
Int J Environ Res Public Health. 2020 Apr 30;17(9), pii: E3123.

Asymptomatic malaria and anemia during pregnancy increase the risk of negative birth outcomes. This cross-sectional study investigated the prevalence and correlates of asymptomatic malaria and anemia during first antenatal care (ANC) visit among pregnant women in a rural district, Tanzania. HIV-uninfected pregnant women without symptoms of malaria (n = 819) attending their first ANC at Kibiti Health Centre were enrolled from February 2017 to February 2018.

NOT Open Access | Asymptomatic Submicroscopic Plasmodium Infection Is Highly Prevalent and Is Associated with Anemia in Children Younger than 5 Years in South Kivu/Democratic Republic of Congo

March 9, 2020 - 14:37 -- NOT Open Access
Author(s): 
Lufungulo Bahati Y, Delanghe J, Bisimwa Balaluka G, Sadiki Kishabongo A, Philippe J
Reference: 
Am J Trop Med Hyg. 2020 Mar 2

One of the most important problems in controlling malaria is the limited access to effective and accurate diagnosis of malaria parasitemia. In the Democratic Republic of Congo (DRC), malaria is one of the leading causes of morbidity and mortality. The purpose of this study was to assess the prevalence of anemia and the relationship with asymptomatic submicroscopic Plasmodium infection.

NOT Open Access | Effects of IgG and IgM autoantibodies on non-infected erythrocytes is related to ABO blood group in Plasmodium vivax malaria and is associated with anemia

March 2, 2020 - 15:27 -- NOT Open Access
Author(s): 
Mourão LC, Medeiros CMP, Braga ÉM, et al.
Reference: 
Microbes Infect. 2020 Feb 22. pii: S1286-4579(20)30031-9

Autoantibodies play an important role in the destruction of non-infected red blood cells (nRBCs) during malaria. However, the relationship between this clearance and ABO blood groups is yet to be fully enlightened, especially for Plasmodium vivax infections. Here we show that anti-RBC IgG and IgM are increased in anemic patients with acute vivax malaria.

NOT open Access | Associations among Soil-Transmitted Helminths, G6PD Deficiency and Asymptomatic Malaria Parasitemia, and Anemia in Schoolchildren from a Conflict Zone of Northeast Myanmar

February 25, 2020 - 13:57 -- NOT Open Access
Author(s): 
Zeng W, Malla P, Xu X, Pi L, Zhao L, He X, He Y, Menezes LJ, Cui L, Yang Z
Reference: 
Am J Trop Med Hyg. 2020 Feb 10


In tropical areas of developing countries, the interactions among parasitic diseases such as soil-transmitted helminths (STHs) and malaria, and glucose-6-phosphate dehydrogenase deficiency (G6PDd), are complex. Here, we investigated their interactions and impact on anemia in school students residing in a conflict zone of northeast Myanmar. A cross-sectional survey was conducted between July and December 2015 in two schools located along the China–Myanmar border.

NOT Open Access | Anemia and transfusion requirements among Ugandan children with severe malaria treated with intravenous artesunate

December 23, 2019 - 14:23 -- NOT Open Access
Author(s): 
Hawkes MT, Opoka RO, Conroy AL, Elphinstone RE, Hume HA, Namasopo S, Kain KC
Reference: 
Pediatr Hematol Oncol. 2019 Dec 12:1-13

Parenteral artesunate for the treatment of severe malaria in non-immune travelers is associated with late-onset hemolysis. In children in sub-Saharan Africa, the hematologic effects of malaria and artesunate are less well documented. Here we report a prospective case series of 91 children with severe malaria treated with parenteral artesunate, managed at a resource-poor hospital in Africa, with longitudinal data on hemoglobin (Hb), lactate dehydrogenase (LDH), haptoglobin, and erythrocyte morphology.

Not Open Access | Prevalence of malaria and anemia among pregnant women residing in malaria-endemic forest villages in India

September 10, 2014 - 16:52 -- NOT Open Access
Author(s): 
Ihtesham Aatif Qureshi, Nimmathota Arlappa, Mohtashim Arbaab Qureshi
Reference: 
International Journal of Gynecology & Obstetrics, Volume 127, Issue 1, October 2014, Page 93

Data were used that had been previously collected by Médecins Sans Frontières India for 1222 pregnant women residing in adjoining forest villages who attended one of seven mobile prenatal-care clinics between January 1 and December 31, 2012.

Not Open Access | A systematic review of the impact of malaria prevention in pregnancy on low birth weight and maternal anemia

April 25, 2013 - 17:00 -- NOT Open Access
Author(s): 
Elizabeth M. McClure, Robert L. Goldenberg, Arlene E. Dent, Steven R. Meshnick
Reference: 
International Journal of Gynecology & Obstetrics, Volume 121, Issue 2, May 2013, Pages 103-109
MalariaWorld

 

To evaluate the association between recommended preventative SP programs in pregnancy and low birth weight (LBW) and maternal anemia through available clinical trial, observational, and programmatic evaluation studies.

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