Artemisinin resistance in Plasmodium falciparum, the agent of severe malaria, is currently a major obstacle to malaria control in Southeast Asia.
Plasmodium ovale is rare and not exactly known to be autochthonous in Malaysia.
Our novel P. ovale rbp2 qPCR assay detects P. ovale curtisi and P. ovale wallikeri simultaneously and can be utilized to characterize the prevalence, distribution, and burden of P. ovale in malaria endemic regions.
Both P. ovale wallikeri and P. ovale curtisi infections are present in imported malaria cases of China.
Only a few late cases of Plasmodium ovale presentation have been reported in literature.
Plasmodium ovale is potentially capable of causing severe complications, if not death.
All three hospitalised patients were originally residents of remote inaccessible forest villages and never moved out of their residence.
ECMO support allowed adequate oxygenation and correction of hypercapnia under lung protective ventilation, therefore reducing ventilator-induced lung injury.
This work explores misclassifications of four Plasmodium species by conventional microscopy in relation to the proficiency of microscopists and morphological characteristics of the parasites on Giemsa-stained blood films.