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Leishmania

Pentacyclic triterpenes in antimalarial plants, a new paradigm

May 8, 2016 - 07:48 -- Pierre Lutgen

Many plants have antiplasmodial properties but nobody really knows why some do and others do not. We have paid most of our attention to artemisinin and derivatives, to flavonoids and antioxidants, swamped and blinded by thousands of papers on these molecules, billions invested and earned in ACTs, the prohibition of clinical trials with Artemisia annua by WHO-Geneva, the Vatican of malaria, and the colonial ITG-Antwerp. And we have forgotten that there are other molecules in Artemisia which may play an equivalent or stronger role.

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'Breakthrough' of the week: Flying syringes

March 19, 2010 - 12:29 -- Bart G.J. Knols

In the early 1990s, when scientists first came up with a radical new idea to engineer mosquitoes that would no longer be capable of transmitting pathogens, some thought of an even more fantastic application. Use mosquitoes to vaccinate people. Silence followed until now...

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