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Parasite clearance, cure rate, post-treatment prophylaxis and safety of standard 3-day versus an extended 6-day treatment of artemether–lumefantrine and a single low-dose primaquine for uncomplicated Plasmodium falciparum malaria in Bagamoyo district, Tan

June 26, 2020 - 15:41 -- Open Access
Lwidiko E. Mhamilawa, Billy Ngasala, Ulrika Morris, Eliford Ngaimisi Kitabi, Rory Barnes, Aung Paing Soe, Bruno P. Mmbando, Anders Björkman and Andreas Mårtensson
Malaria Journal 2020 19:216, 23 June 2020

Artemisinin-based combination therapy (ACT) resistant Plasmodium falciparum represents an increasing threat to Africa. Extended ACT regimens from standard 3 to 6 days may represent a means to prevent its development and potential spread in Africa.

Household factors associated with access to insecticide-treated nets and house modification in Bagamoyo and Ulanga districts, Tanzania

June 26, 2020 - 11:02 -- Open Access
Olukayode G. Odufuwa, Amanda Ross, Yeromin P. Mlacha, Omary Juma, Selemani Mmbaga, Daniel Msellemu and Sarah Moore
Malaria Journal 2020 19:220, 23 June 2020

Insecticide-treated nets (ITNs) and house modifications are proven vector control tools, yet in most regions, full coverage has not been achieved. This study investigates household factors associated with access to ITNs and house modification in Tanzania.

Aquatic habitats of the malaria vector Anopheles funestus in rural south-eastern Tanzania

June 26, 2020 - 11:00 -- Open Access
Ismail H. Nambunga, Halfan S. Ngowo, Fredros O. Okumu, et al.
Malaria Journal 2020 19:219, 23 June 2020

In rural south-eastern Tanzania, Anopheles funestus is a major malaria vector, and has been implicated in nearly 90% of all infective bites. Unfortunately, little is known about the natural ecological requirements and survival strategies of this mosquito species.

High malaria parasitemia among outpatient febrile children in low endemic area, East-Central Tanzania in 2013

May 25, 2020 - 11:41 -- Open Access
Chipwaza B, Sumaye RD
BMC Res Notes. 2020 May 24; 13(1):251

This study investigated the prevalence and distribution patterns of malaria in Kilosa district as part of non-malaria causes of febrile illnesses in children study. We enrolled febrile patients aged 2–13 years presenting at the outpatient department during the rainy and dry seasons, in 2013. For each participant, we tested for malaria parasites and identified parasite species using microscopy. We then calculated parasite density and estimated geometric mean parasite density.

NOT Open Access | Mean platelet counts are relatively decreased with malaria but relatively increased with endemic Burkitt Lymphoma in Uganda, Tanzania, and Kenya

May 13, 2020 - 14:54 -- NOT Open Access
Peprah S, Ogwang MD, Mbulaiteye SM, et al.
Br J Haematol. 2020 May 12

Platelet counts are decreased in Plasmodium falciparum malaria, which is aetiologically linked with endemic Burkitt lymphoma (eBL). However, the pattern of platelet counts in eBL cases is unknown. We studied platelet counts in 582 eBL cases and 2 248 controls enrolled in a case‐control study in Uganda, Tanzania and Kenya (2010–2016). Mean platelet counts in controls or eBL cases with or without malaria‐infection in controls versus eBLcases were compared using Student’s t‐test.

Sub-national stratification of malaria risk in mainland Tanzania: a simplified assembly of survey and routine data

May 12, 2020 - 16:37 -- Open Access
Sumaiyya G. Thawer, Frank Chacky, Fabrizio Molteni, et al.
Malaria Journal 2020 19:177, 8 May 2020

Recent malaria control efforts in mainland Tanzania have led to progressive changes in the prevalence of malaria infection in children, from 18.1% (2008) to 7.3% (2017). As the landscape of malaria transmission changes, a sub-national stratification becomes crucial for optimized cost-effective implementation of interventions. This paper describes the processes, data and outputs of the approach used to produce a simplified, pragmatic malaria risk stratification of 184 councils in mainland Tanzania.

Prevalence and Correlates of Asymptomatic Malaria and Anemia on First Antenatal Care Visit among Pregnant Women in Southeast, Tanzania

May 6, 2020 - 15:54 -- Open Access
Mlugu EM, Minzi O, Kamuhabwa AAR, Aklillu E
Int J Environ Res Public Health. 2020 Apr 30;17(9), pii: E3123.

Asymptomatic malaria and anemia during pregnancy increase the risk of negative birth outcomes. This cross-sectional study investigated the prevalence and correlates of asymptomatic malaria and anemia during first antenatal care (ANC) visit among pregnant women in a rural district, Tanzania. HIV-uninfected pregnant women without symptoms of malaria (n = 819) attending their first ANC at Kibiti Health Centre were enrolled from February 2017 to February 2018.

Opinions of key stakeholders on alternative interventions for malaria control and elimination in Tanzania

April 23, 2020 - 10:29 -- Open Access
Marceline F. Finda, Nicola Christofides, Javier Lezaun, Brian Tarimo, Prosper Chaki, Ann H. Kelly, Ntuli Kapologwe, Paul Kazyoba, Basiliana Emidi and Fredros O. Okumu
Malaria Journal 2020 19:164, 23 April 2020

Malaria control in Tanzania currently relies primarily on long-lasting insecticidal nets and indoor residual spraying, alongside effective case management and behaviour change communication. This study explored opinions of key stakeholders on the national progress towards malaria elimination, the potential of currently available vector control interventions in helping achieve elimination by 2030, and the need for alternative interventions that could be used to supplement malaria elimination efforts in Tanzania.

Effect of sulfadoxine-pyrimethamine doses for prevention of malaria during pregnancy in hypoendemic area in Tanzania

April 20, 2020 - 09:51 -- Open Access
Wigilya P. Mikomangwa, Omary Minzi, Ritah Mutagonda, Vito Baraka, Eulambius M. Mlugu, Eleni Aklillu and Appolinary A. R. Kamuhabwa
Malaria Journal 2020 19:160, 19 April 2020

Malaria in pregnancy increases the risk of deleterious maternal and birth outcomes. The use of ≥ 3 doses of sulfadoxine-pyrimethamine (SP) for intermittent preventive treatment of malaria (IPTp-SP) is recommended for preventing the consequences of malaria during pregnancy. This study assessed the effect of IPTp-SP for prevention of malaria during pregnancy in low transmission settings.

Sustaining LLIN coverage with continuous distribution: the school net programme in Tanzania

April 20, 2020 - 09:04 -- Open Access
Joshua Yukich, Logan Stuck, Hannah Koenker, et al.
Malaria Journal 2020 19:158, 17 April 2020

Most malaria-endemic countries have struggled in the past decade to establish effective national-scale continuous distribution mechanisms for long-lasting insecticidal nets (LLINs). Since the implementation of the Tanzania National Voucher Scheme in 2004 and mass-distribution campaigns in 2009–2011 and 2015–2016, Tanzania has been committed to finding new and innovative ways of achieving and maintaining universal bed net coverage.


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