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malaria transmission

The persistence of naturally acquired antibodies and memory B cells specific to rhoptry proteins of Plasmodium vivax in patients from areas of low malaria transmission

December 2, 2019 - 15:04 -- Open Access
Author(s): 
Kochayoo P, Changrob S, Wangriatisak K, Lee SK, Chootong P, Han ET
Reference: 
Malaria Journal volume 18, 382 (2019)

Rhoptries are the large, paired, secretory organelles located at the apical tip of the malaria merozoite that are considered important for parasite invasion processes. Plasmodium vivax rhoptry proteins have been shown to induce humoral immunity during natural infections. Therefore, these proteins may be potential novel vaccine candidates. However, there is a lack of data on the duration of antibody and memory B cell (MBC) responses. Here, the longitudinal analysis of antibody and MBC responses to the P. vivax rhoptry proteins PvRALP1-Ecto and PvRhopH2 were monitored and analysed in individuals to determine their persistence.

Not Open Access | Stability and bifurcation analysis of a vector-bias model of malaria transmission

February 6, 2013 - 14:26 -- NOT Open Access
Author(s): 
Bruno Buonomo, Cruz Vargas-De-León
Reference: 
Mathematical Biosciences, Volume 242, Issue 1, March 2013, Pages 59–67
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This implies that a stable endemic equilibrium may also exists for R0<1. When R0>1, the endemic persistence of the disease has been proved to hold also for the extended model. This last result is obtained by means of the geometric approach to global stability.

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