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p. berghei

A genetically hmgb2 attenuated blood stage P. berghei induces crossed-long live protection

May 12, 2020 - 16:47 -- Open Access
Briquet S, Lawson-Hogban N, Peronet R, Mécheri S, Vaquero C
PLoS ONE 15(5): e0232183

Due to the lack of efficiency to control malaria elicited by sub-unit vaccine preparations, vaccination with live-attenuated Plasmodium parasite as reported 70 years ago with irradiated sporozoites regained recently a significant interest. The complex life cycle of the parasite and the different stages of development between mammal host and anopheles do not help to propose an easy vaccine strategy.

In vivo antiplasmodial and toxicological effect of crude ethanol extract of Echinops kebericho traditionally used in treatment of malaria in Ethiopia

May 12, 2015 - 11:15 -- Open Access
Alemayehu Toma, Serawit Deyno, Abrham Fikru, Amalework Eyado, Andrew Beale
Malaria Journal 2015, 14:196 (10 May 2015)

The result revealed the ethanol extract of E. kebericho roots has anti-malarial activity against P. berghei in an animal model and lends support to the use of the plant to combat malaria in Ethiopian folk medicine.

Phenotypic Dissection of a Plasmodium-Refractory Strain of Malaria Vector Anopheles stephensi: The Reduced Susceptibility to P. berghei and P. yoelii

June 15, 2013 - 11:30 -- Open Access
Naoaki Shinzawa, Tomoko Ishino, Mayumi Tachibana, Takafumi Tsuboi, Motomi Torii
PLoS ONE 8(5): e63753

Anopheline mosquitoes are the major vectors of human malaria.

NOT Open Access | Protective role of brain water channel AQP4 in murine cerebral malaria

January 17, 2013 - 12:54 -- NOT Open Access
Dominique Promeneur, Lisa Kristina Lunde, Mahmood Amiry-Moghaddam, and Peter Agre
PNAS January 15, 2013 vol. 110 no. 3 1035-1040

Tragically common among children in sub-Saharan Africa, cerebral malaria is characterized by rapid progression to coma and death.

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