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NOT Open Access | cGMP Signalling: Malarial Guanylyl Cyclase Leads the Way

September 13, 2018 - 17:27 -- NOT Open Access
Mathieu Brochet
Current Biology Volume 28, Issue 17, 10 September 2018, Pages R939-R941

When ingested by a mosquito, the malaria parasite relies on an unusual form of gliding motility to escape from the rapidly deteriorating blood meal.

Seeing is believing: the nocturnal malarial mosquito Anopheles coluzzii responds to visual host-cues when odour indicates a host is nearby

June 8, 2016 - 16:07 -- Open Access
Hawkes F, Gibson G
Parasites & Vectors 2016, 9:320 (3 June 2016)

The immediate aim of our study was to analyse the behaviour of the malarial mosquito Anopheles coluzzii (An. gambiae species complex) near a human host with the ultimate aim of contributing to our fundamental understanding of mosquito host-seeking behaviour and the overall aim of identifying behaviours that could be exploited to enhance sampling and control strategies.

Suboptimal larval habitats modulate oviposition of the malaria vector mosquito Anopheles gambiae s.s.

September 24, 2015 - 14:46 -- Open Access
Eunho Suh, Dong-Hwan Choe, Ahmed M Saveer, Laurence J Zwiebel

Taken together, these findings validate the hypothesis in question and suggest that suboptimal environments for An. gambiae larval development results in the release of DMDS, DMTS and sulcatone that impact the response valence of gravid females to directly modulate the chemical ecology of oviposition site selection.

New antibody insecticide targets malaria mosquito

May 23, 2015 - 11:17 -- Open Access
Kathryn Knight
J Exp Biol 218, 1461-1462, May 15, 2015

However, little was known about how Ivermectin targets mosquitoes – it was developed to treat diseases in nematodes – so Meyers, Brian Foy and a team of colleagues from Colorado State University, including Meg Gray, Wojtek Kuklinski, Lucas Johnson, Christopher Snow, William Black IV and Kathryn Partin, decided to find out more about the drug's modus operandi.

Malaria Parasites Produce Volatile Mosquito Attractants

May 5, 2015 - 15:26 -- Open Access
Megan Kelly, Chih-Ying Su, Chad Schaber, Jan R. Crowley, Fong-Fu Hsu, John R. Carlson, Audrey R. Odom
mBio vol. 6 no. 2 e00235-15, 24 March 2015

In this work, we describe the volatile chemical profile of cultured malaria parasites. Among the identified compounds are several plant-like terpenes and terpene derivatives, including known mosquito attractants.

In depth annotation of the Anopheles gambiae mosquito midgut transcriptome

August 8, 2014 - 18:08 -- Open Access
Padrón A, Molina-Cruz A, Quinones M, Ribeiro JM, Ramphul U, Rodrigues J, Shen K, Haile A, Ramirez J, Barillas-Mury C
BMC Genomics 2014, 15 :636 (29 July 2014)

This in-depth Illumina sequencing and assembly of the An. gambiae midgut transcriptome doubled the number of known transcripts and tripled the number of variants known in this mosquito species.

Should we broaden our attack on mosquitoes to maintain and improve national support?

July 2, 2014 - 10:53 -- William Jobin

One of the weaknesses in our fight against malaria is that we are missing the opportunity to attack other mosquito-transmitted diseases. It is the weakness of any "vertical" approach to disease control.

Pyriproxyfen for mosquito control: female sterilization or horizontal transfer to oviposition substrates by Anopheles gambiae sensu stricto and Culex quinquefasciatus

July 1, 2014 - 18:17 -- Open Access
Mbare O, Lindsay SW, Fillinger U
Parasites & Vectors 2014, 7 :280 (21 June 2014)

We explore the effect of PPF exposure at seven time points around blood feeding on individual Anopheles gambiae sensu stricto and Culex quinquefasciatus fecundity and ability to transfer in laboratory assays.

Not Open Access | Blood feeding induces hemocyte proliferation and activation in the African malaria mosquito, Anopheles gambiae Giles

May 6, 2014 - 17:11 -- NOT Open Access
William B. Bryant and Kristin Michel
The Journal of Experimental Biology , J Exp Biol 217, 1238-1245 , April 15, 2014

Taken together, this study demonstrates that the normal physiological process of a blood meal activates the innate immune response in mosquitoes. This process is likely in part regulated by Ras-MAPK signaling, highlighting a novel mechanistic link between blood feeding and immunity.


Evaluating local vegetation cover as a risk factor for malaria transmission: a new analytical approach using ImageJ

April 8, 2014 - 20:11 -- Open Access
Ricotta EE, Frese SA, Choobwe C, Louis TA, Shiff CJ
Malaria Journal 2014, 13 :94 (13 March 2014)

Analysis of this vegetation can be done using satellite information and mapping programs, such as Google Earth, but manual quantification is difficult and can be tedious and subjective. A more objective method is required.


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