The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10364 malaria professionals are enjoying the free benefits of MalariaWorld today


Video Recording Can Conveniently Assay Mosquito Locomotor Activity

March 23, 2020 - 14:54 -- Open Access
Araujo MDS, Guo F, Rosbash M
Sci Rep. 2020 Mar 19;10(1):4994

Anopheles gambiae and Aedes aegypti are perhaps the best studied mosquito species and important carriers of human malaria and arbovirus, respectively. Mosquitoes have daily rhythms in behaviors and show a wide range of activity patterns. Although Anopheles is known to be principally nocturnal and Aedes principally diurnal, details of mosquito activity are not easily assayed in the laboratory.

NOT Open Access | Surprising differences in the respiratory protein of insects: A spectroscopic study of haemoglobin from the European honeybee and the malaria mosquito

March 19, 2020 - 09:01 -- NOT Open Access
Nys K, Cuypers B, Berghmans H, Hammerschmid D, Moens L, Dewilde S, Van Doorslaer S
Biochim Biophys Acta Proteins Proteom. 2020 Mar 13 :140413

Only recently it was discovered that haemoglobin (Hb) belongs to the standard gene repertoire of insects, although their tracheal system is used for respiration. A classical oxygen-carrying function of Hb is only obvious for hexapods living in hypoxic environments.

Creating mosquito-free outdoor spaces using transfluthrin-treated chairs and ribbons

March 18, 2020 - 14:46 -- Open Access
John P. Masalu, Marceline Finda, Gerry F. Killeen, Halfan S. Ngowo, Polius G. Pinda and Fredros O. Okumu
Malaria Journal 2020 19:109, 10 March 2020

Residents of malaria-endemic communities spend several hours outdoors performing different activities, e.g. cooking, story-telling or eating, thereby exposing themselves to potentially-infectious mosquitoes. This compromises effectiveness of indoor interventions, notably long-lasting insecticide-treated nets (LLINs) and indoor residual spraying (IRS). This study characterized common peri-domestic spaces in rural south-eastern Tanzania, and assessed protective efficacy against mosquitoes of hessian fabric mats and ribbons treated with the spatial repellent, transfluthrin, and fitted to chairs and outdoor kitchens, respectively.

Cas9-Mediated Gene-Editing in the Malaria Mosquito Anopheles stephensi by ReMOT Control

March 9, 2020 - 14:26 -- Open Access
Macias VM, McKeand S, Chaverra-Rodriguez D, Hughes GL, Fazekas A, Pujhari S, Jasinskiene N, James AA, Rasgon JL
G3 (Bethesda). 2020 Mar 2. pii: g3.401133.2020

Innovative tools are essential for advancing malaria control and depend on an understanding of molecular mechanisms governing transmission of malaria parasites by Anopheles mosquitoes. CRISPR/Cas9-based gene disruption is a powerful method to uncover underlying biology of vector-pathogen interactions and can itself form the basis of mosquito control strategies. However, embryo injection methods used to genetically manipulate mosquitoes (especially Anopheles) are difficult and inefficient, particularly for non-specialist laboratories.

Consequences of larval competition and exposure to permethrin for the development of the rodent malaria Plasmodium berghei in the mosquito Anopheles gambiae

March 3, 2020 - 13:07 -- Open Access
Hauser G, Thiévent K, Koella JC
Parasites & Vectors, 2020 Feb 27;13(1):107

Mosquitoes and other vectors are often exposed to sublethal doses of insecticides. Larvae can be exposed to the run-off of agricultural use, and adults can be irritated by insecticides used against them and move away before they have picked up a lethal dose. This sublethal exposure may affect the success of control of insect-borne diseases, for it may affect the competence of insects to transmit parasites, in particular if the insects are undernourished.

Not Open Access | A Plasmodium key fits a mosquito lock

February 17, 2020 - 12:27 -- NOT Open Access
Cha SJ, Jacobs-Lorena M
Proc Natl Acad Sci U S A. 2020 Feb 5. pii: 202000122

Malaria is one of the three most lethal infectious diseases. Unlike AIDS and tuberculosis, malaria is unique in that the parasite must complete a complex differentiation program in its mosquito vector for transmission to occur (1) (Fig. 1). Despite significant progress made in the last couple of decades, our mechanistic understanding of how the parasite develops in the mosquito is incomplete.

NOT Open Access | Mosquito heat seeking is driven by an ancestral cooling receptor

February 17, 2020 - 12:19 -- NOT Open Access
Greppi C, Laursen WJ, Budelli G, Chang EC, Daniels AM, van Giesen L, Smidler AL, Catteruccia F, Garrity PA
Science 07 Feb 2020, Vol. 367, Issue 6478, pp. 681-684

Mosquitoes transmit pathogens that kill >700,000 people annually. These insects use body heat to locate and feed on warm-blooded hosts, but the molecular basis of such behavior is unknown. Here, we identify ionotropic receptor IR21a, a receptor conserved throughout insects, as a key mediator of heat seeking in the malaria vector Anopheles gambiae.

Direct and indirect effects of predation and parasitism on the Anopheles gambiae mosquito

February 10, 2020 - 15:47 -- Open Access
Fedinand Ong’wen, Patrick Ogola Onyango, Tullu Bukhari
Parasites Vectors 13, 43 (2020)

A good understanding of mosquito ecology is imperative for integrated vector control of malaria. In breeding sites, Anopheles larvae are concurrently exposed to predators and parasites. However, to our knowledge, there is no study on combined effects of predators and parasites on development and survival of larvae and their carry-over effects on adult survivorship and susceptibility to further parasite infection.

Estimating spatio-temporal distributions of mosquito breeding pools in irrigated agricultural schemes: a case study at the Bwanje Valley Irrigation Scheme

January 27, 2020 - 13:28 -- Open Access
April N. Frake, Willy Namaona, Edward D. Walker and Joseph P. Messina
Malaria Journal 2020 19:38, 22 January 2020

The association between irrigation and the proliferation of adult mosquitoes including malaria vectors is well known; however, irrigation schemes are treated as homogenous spatio-temporal units, with little consideration for how larval breeding varies across space and time. The objective of this study was to estimate the spatio-temporal distribution of pools of water facilitating breeding at the Bwanje Valley Irrigation Scheme (BVIS) in Malawi, Africa as a function of environmental and anthropogenic characteristics.

Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development

December 23, 2019 - 14:21 -- Open Access
Lampe L, Jentzsch M, Kierszniowska S, Levashina EA
Nat Commun. 2019 Dec 10; 10 (1):5634

The blood-feeding behavior of Anopheles females delivers essential nutrients for egg development and drives parasite transmission between humans. Plasmodium growth is adapted to the vector reproductive cycle, but how changes in the reproductive cycle impact parasite development remains unclear. Here, we show that the bloodmeal-induced miR-276-5p fine-tunes the expression of branched-chain amino acid transferase to terminate the reproductive cycle.


Subscribe to RSS - mosquito