The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10651 malaria professionals are enjoying the free benefits of MalariaWorld today

Ghana

Prevalence of sickle cell disorders and malaria infection in children aged 1–12 years in the Volta Region, Ghana: a community-based study

November 24, 2020 - 14:59 -- Open Access
Author(s): 
Mavis Oppong, Helena Lamptey, Eric Kyei-Baafour, Belinda Aculley, Ebenezer Addo Ofori, Bernard Tornyigah, Margaret Kweku and Michael F. Ofori
Reference: 
Malaria Journal 2020 19:426, 23 November 2020

Alterations in the structure of haemoglobin (Hb) are usually brought about by point mutations affecting one or, in some cases, two codons encoding amino acids of the globin chains. One in three Ghanaians are said to have sickle cell disorders, whereas malaria continues to be one of the leading causes of mortality among children. This study determined the prevalence of sickle cell disorders and malaria infection among children aged 1–12 years in the Volta Region.

Accounting for regional transmission variability and the impact of malaria control interventions in Ghana: a population level mathematical modelling approach

November 24, 2020 - 14:52 -- Open Access
Author(s): 
Timothy Awine and Sheetal P. Silal
Reference: 
Malaria Journal 2020 19:423, 23 November 2020

This paper investigates the impact of malaria preventive interventions in Ghana and the prospects of achieving programme goals using mathematical models based on regionally diverse climatic zones of the country.

Epidemiology of malaria among pregnant women during their first antenatal clinic visit in the middle belt of Ghana: a cross sectional study

October 27, 2020 - 15:55 -- Open Access
Author(s): 
David Kwame Dosoo, Daniel Chandramohan, Seth Owusu-Agyei, et al.
Reference: 
Malaria Journal 2020 19:381, 23 October 2020

Malaria during pregnancy may result in unfavourable outcomes in both mothers and their foetuses. This study sought to document the current burden and factors associated with malaria and anaemia among pregnant women attending their first antenatal clinic visit in an area of Ghana with perennial malaria transmission.

Profiles of Plasmodium falciparum infections detected by microscopy through the first year of life in Kintampo a high transmission area of Ghana

October 21, 2020 - 08:36 -- Open Access
Author(s): 
Botwe AK, Owusu-Agyei S, Asghar M, Hammar U, Oppong FB, Gyaase S, Dosoo D, Jakpa G, Boamah E, Twumasi MF, Osier F, Färnert A, Asante KP
Reference: 
PLoS One. 2020 Oct 19;15(10):e0240814

Although malaria mortality among children under five years of age is high, the characteristics of their infection patterns are not well described. The aim of this study was to examine the longitudinal sequence pattern of Plasmodium falciparum infections in the first year of life within a birth cohort in Kintampo, Ghana (N = 1855). Infants were monitored at home with monthly sampling and also at the clinic for any febrile illness between 2008 and 2011.

High prevalence of asymptomatic malaria infections in adults, Ashanti Region, Ghana, 2018

October 14, 2020 - 12:25 -- Open Access
Author(s): 
Melina Heinemann, Richard O. Phillips, Christof D. Vinnemeier, Christina C. Rolling, Egbert Tannich and Thierry Rolling
Reference: 
Malaria Journal 2020 19:366, 14 October 2020

Ghana is among the high-burden countries for malaria infections and recently reported a notable increase in malaria cases. While asymptomatic parasitaemia is increasingly recognized as a hurdle for malaria elimination, studies on asymptomatic malaria are scarce, and usually focus on children and on non-falciparum species. The present study aims to assess the prevalence of asymptomatic Plasmodium falciparum and non-falciparum infections in Ghanaian adults in the Ashanti region during the high transmission season.

High prevalence of asymptomatic malaria infections in adults, Ashanti Region, Ghana, 2018

October 13, 2020 - 12:43 -- Open Access
Author(s): 
Melina Heinemann, Richard O. Phillips, Christof D. Vinnemeier, Christina C. Rolling, Egbert Tannich and Thierry Rolling
Reference: 
Malaria Journal 2020 19:366, 12 October 2020

Ghana is among the high-burden countries for malaria infections and recently reported a notable increase in malaria cases. While asymptomatic parasitaemia is increasingly recognized as a hurdle for malaria elimination, studies on asymptomatic malaria are scarce, and usually focus on children and on non-falciparum species. The present study aims to assess the prevalence of asymptomatic Plasmodium falciparum and non-falciparum infections in Ghanaian adults in the Ashanti region during the high transmission season.

Comparison of leucocyte profiles between healthy children and those with asymptomatic and symptomatic Plasmodium falciparum infections

October 13, 2020 - 12:39 -- Open Access
Author(s): 
Diana Ahu Prah, Linda Eva Amoah, Matthew P. Gibbins, Yaw Bediako, Aubrey J. Cunnington, Gordon A. Awandare and Julius Clemence R. Hafalla
Reference: 
Malaria Journal 2020 19:364, 9 October 2020

The immune mechanisms that determine whether a Plasmodium falciparum infection would be symptomatic or asymptomatic are not fully understood. Several studies have been carried out to characterize the associations between disease outcomes and leucocyte numbers. However, the majority of these studies have been conducted in adults with acute uncomplicated malaria, despite children being the most vulnerable group.

Evaluating the potential of using urine and saliva specimens for malaria diagnosis in suspected patients in Ghana

October 1, 2020 - 15:32 -- Open Access
Author(s): 
Enoch Aninagyei, Joseph Abraham, Paul Atiiga, Shadrach Duodu Antwi, Stephen Bamfo and Desmond Omane Acheampong
Reference: 
Malaria Journal 2020 19:349, 29 September 2020

This study aimed at detecting PfHRP2 and pLDH malaria antigens in urine and salivary specimens of suspected malaria patients using RDT kits, and identifying factors influencing the detection of these antigens.

Managing intermittent preventive treatment of malaria in pregnancy challenges: an ethnographic study of two Ghanaian administrative regions

September 29, 2020 - 13:04 -- Open Access
Author(s): 
Matilda Aberese-Ako, Pascal Magnussen, Margaret Gyapong, Gifty D. Ampofo and Harry Tagbor
Reference: 
Malaria Journal 2020 19:347, 25 September 2020

Malaria in pregnancy (MiP) is an important public health problem across sub-Saharan Africa. The package of measures for its control in Ghana in the last 20 years include regular use of long-lasting insecticide-treated bed nets (LLINs), directly-observed administration (DOT) of intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) and prompt and effective case management of MiP. Unfortunately, Ghana like other sub-Saharan African countries did not achieve the reset Abuja targets of 100% of pregnant women having access to IPTp and 100% using LLINs by 2015.

Will More of the Same Achieve Malaria Elimination? Results from an Integrated Macroeconomic Epidemiological Demographic Model

September 23, 2020 - 09:32 -- Open Access
Author(s): 
Smith RD, Keogh-Brown MR, Chico RM, Bretscher MT, Drakeley C, Jensen HT
Reference: 
Am J Trop Med Hyg. 2020 Sep 21

Historic levels of funding have reduced the global burden of malaria in recent years. Questions remain, however, as to whether scaling up interventions, in parallel with economic growth, has made malaria elimination more likely today than previously. The consequences of "trying but failing" to eliminate malaria are also uncertain. Reduced malaria exposure decreases the acquisition of semi-immunity during childhood, a necessary phase of the immunological transition that occurs on the pathway to malaria elimination.

Pages

Subscribe to RSS - Ghana