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long-lasting insecticidal nets (LLINs)

Monitoring the durability of the long-lasting insecticidal nets MAGNet and Royal Sentry in three ecological zones of Mozambique

June 22, 2020 - 16:32 -- Open Access
Ana Paula Abílio, Emmanuel Obi, Albert Kilian, et al.
Malaria Journal 2020 19:209, 17 June 2020

Malaria prevention with long-lasting insecticidal nets (LLINs) has seen a tremendous scale-up in sub-Saharan Africa in the last decade. To sustain this success, it is important to understand how long LLINs remain in the households and continue to protect net users, which is termed durability. This information is needed to decide the appropriate timing of LLIN distribution and also to identify product(s) that may be underperforming relative to expectations. Following guidance from the U.S. President’s Malaria Initiative, durability monitoring of polyethylene 150-denier LLIN (Royal Sentry® and MAGNet®) distributed during a 2017 mass campaign in Mozambique was implemented in three ecologically different sites: Inhambane, Tete, and Nampula.

Acetylcholinesterase (ace-1R) target site mutation G119S and resistance to carbamates in Anopheles gambiae (sensu lato) populations from Mali

June 8, 2020 - 15:41 -- Open Access
Keïta M, Kané F, Thiero O, Traoré B, Zeukeng F, Sodio AB, Traoré SF, Djouaka R, Doumbia S, Sogoba N
Parasit Vectors. 2020 Jun 5; 13(1):283

The long-lasting insecticidal nets (LLINs) and indoor residual spraying of insecticide (IRS) are major malaria vector control strategies in Mali. The success of control strategies depends on a better understanding of the status of malaria vectors with respect to the insecticides used. In this study we evaluate the level of resistance of Anopheles gambiae (sensu lato) to bendiocarb and the molecular mechanism that underlies it.

The epidemiology of Plasmodium falciparum and Plasmodium vivax in East Sepik Province, Papua New Guinea, pre- and post-implementation of national malaria control efforts

June 8, 2020 - 15:18 -- Open Access
Johanna H. Kattenberg, Dulcie L. Gumal, Leanne J. Robinson, et al.
Malaria Journal 2020 19:198, 5 June 2020

In the past decade, national malaria control efforts in Papua New Guinea (PNG) have received renewed support, facilitating nationwide distribution of free long-lasting insecticidal nets (LLINs), as well as improvements in access to parasite-confirmed diagnosis and effective artemisinin-combination therapy in 2011–2012.

Evaluation of bio-efficacy and durability of long-lasting insecticidal nets distributed by malaria elimination programme in Eastern India

May 25, 2020 - 08:38 -- Open Access
Sudhansu Sekhar Sahu, Amol Vasantrao Keshaowar, Sonia Thankachy, Dilip Kumar Panigrahi, Premalata Acharya, Vijayakumar Balakrishnan and Ashwani Kumar
Malaria Journal 2020 19:186, 24 May 2020

Long-lasting insecticidal nets (LLINs) are the most favoured vector control tools worldwide. Timely monitoring and evaluation of LLINs is important to sustain the impact of this promising vector control method and for replacement of worn-out and those rendered ineffective. During the mid-2017, LLINs were distributed by the National Vector Borne Disease Control Programme (NVBDCP) in high malaria endemic districts of the eastern coastal state of Odisha. The study was carried out to assess the field performance of the LLINs post 30 months of distribution in Koraput district of Odisha state.

NOT Open Access | Long-lasting insecticidal nets and the quest for malaria eradication: a mathematical modeling approach

May 25, 2020 - 08:13 -- NOT Open Access
Enahoro I, Eikenberry S, Gumel AB, Huijben S, Paaijmans K
J Math Biol. 2020 May 23

Recent dramatic declines in global malaria burden and mortality can be largely attributed to the large-scale deployment of insecticidal-based measures, namely long-lasting insecticidal nets (LLINs) and indoor residual spraying. However, the sustainability of these gains, and the feasibility of global malaria eradication by 2040, may be affected by increasing insecticide resistance among the Anopheles malaria vector.

Resistance status of Anopheles gambiae s.l. to insecticides following the 2011 mass distribution campaign of long-lasting insecticidal nets (LLINs) in the Plateau Department, south-eastern Benin

January 20, 2020 - 15:50 -- Open Access
Arthur Sovi, Renaud Govoétchan, Martin Codjo Akogbeto, et al.
Malaria Journal 2020 19:26, 15 January 2020

In 2011, Benin’s National Malaria Control Programme (NMCP) organized a nationwide mass distribution campaign of LLINs throughout the country. Following this intervention, it was important to assess whether the level of susceptibility of malaria vectors to insecticides had remained the same as compared to the pre-intervention period. The current study investigated this.

Mosquito feeding behavior and how it influences residual malaria transmission across Africa

July 29, 2019 - 15:04 -- Open Access
Ellie Sherrard-Smith, Janetta E. Skarp, Thomas S. Churcher, et al.
PNAS July 23, 2019 116 (30) 15086-15095

The antimalarial efficacy of the most important vector control interventions—long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS)—primarily protect against mosquitoes’ biting people when they are in bed and indoors.

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Characterizing the molecular and metabolic mechanisms of insecticide resistance in Anopheles gambiae in Faranah, Guinea

July 21, 2019 - 21:48 -- Open Access
Caleb Stica, Claire L. Jeffries, Seth R. Irish, Yaya Barry, Denka Camara, Ismael Yansane, Mojca Kristan, Thomas Walker and Louisa A. Messenger
Malaria Journal 2019 18:244, 17 July 2019

In recent years, the scale-up of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) has greatly reduced malaria transmission. However, malaria remains a global public health concern with the majority of the disease burden in sub-Saharan Africa. Insecticide resistance is a growing problem among Anopheles vector populations, with potential implications for the continued effectiveness of available control interventions. Improved understanding of current resistance levels and underlying mechanisms is essential to design appropriate management strategies and to mitigate future selection for resistance.

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High-accuracy detection of malaria vector larval habitats using drone-based multispectral imagery

January 26, 2019 - 14:59 -- Open Access
Gabriel Carrasco-Escobar, Edgar Manrique, Dionicia Gamboa, et al.
PLoS Negl Trop Dis 13(1): e0007105

Interest in larval source management (LSM) as an adjunct intervention to control and eliminate malaria transmission has recently increased mainly because long-lasting insecticidal nets (LLINs) and indoor residual spray (IRS) are ineffective against exophagic and exophilic mosquitoes.

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Reshaping the vector control strategy for malaria elimination in Ethiopia in the context of current evidence and new tools: opportunities and challenges

December 6, 2018 - 16:49 -- Open Access
Taye Gari and Bernt Lindtjørn
Malaria Journal 2018 17:454, 5 December 2018

The core vector control measures, long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS), reduce the risk of malaria infection by targeting indoor biting mosquitoes.

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