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Tracking progress towards malaria elimination in China: Individual-level estimates of transmission and its spatiotemporal variation using a diffusion network approach

March 24, 2020 - 12:40 -- Open Access
Routledge I, Lai S, Battle KE, Ghani AC, Gomez-Rodriguez M, Gustafson KB, Mishra S, Unwin J, Proctor JL, Tatem AJ, Li Z, Bhatt S
PLoS Comput Biol 16(3): e1007707

In order to monitor progress towards malaria elimination, it is crucial to be able to measure changes in spatio-temporal transmission. However, common metrics of malaria transmission such as parasite prevalence are under powered in elimination contexts. China has achieved major reductions in malaria incidence and is on track to eliminate, having reporting zero locally-acquired malaria cases in 2017 and 2018. Understanding the spatio-temporal pattern underlying this decline, especially the relationship between locally-acquired and imported cases, can inform efforts to maintain elimination and prevent re-emergence.

Not Open Access | Malaria Elimination in China: Improving County-Level Malaria Personnel Knowledge of the 1-3-7 Strategy through Tabletop Exercises

March 2, 2020 - 15:49 -- NOT Open Access
Cao Y, Cotter C, Wang W, Liu Y, Zhou H, Zhu G, Cao J
Am J Trop Med Hyg. 2020 Feb 24

As China moves to the prevention of reestablishment of malaria, maintaining skills for malaria in county personnel on the “1-3-7” surveillance and response strategy is critical. China’s “1-3-7” strategy defines targets used to guide and monitor malaria case reporting, investigation, and response, respectively: reporting of malaria cases within 1 day, their confirmation and investigation within 3 days, and the appropriate public health response to prevent further transmission within 7 days. Assessing the knowledge of local CDC malaria personnel on the “1-3-7” surveillance and response strategy is urgently needed.

Malaria in China: a longitudinal population-based surveillance study

March 2, 2020 - 14:12 -- Open Access
Ding C, Huang C, Zhou Y, Fu X, Liu X, Wu J, Deng M, Li L, Yang S
Epidemiol Infect. 2020 Feb 24; 148:e37

This study aims to ascertain the long-term epidemic trends of malaria and evaluates the probability of achieving the eradication goal by 2020 in China. Data on malaria incidence and deaths were extracted from the China Information System for Disease Control and Prevention. The epidemic trends by sex, age and spatial distribution and predictions of malaria were estimated by using Joinpoint and Poisson regressions.

Molecular surveillance of Pfcrt and k13 propeller polymorphisms of imported Plasmodium falciparum cases to Zhejiang Province, China between 2016 and 2018

February 10, 2020 - 16:08 -- Open Access
Xiaoxiao Wang, Wei Ruan, Shuisen Zhou, Fang Huang, Qiaoyi Lu, Xinyu Feng and He Yan
Malaria Journal 2020 19:59, 4 February 2020

Resistance to anti-malarial drugs hinders malaria elimination. Monitoring the molecular markers of drug resistance helps improve malaria treatment policies. This study aimed to assess the distribution of molecular markers of imported Plasmodium falciparum infections.

Genetic polymorphism of histidine rich protein 2 in Plasmodium falciparum isolates from different infection sources in Yunnan Province, China

January 6, 2020 - 16:05 -- Open Access
Ying Dong, Shuping Liu, Yan Deng, Yanchun Xu, Mengni Chen, Yan Liu and Jingpo Xue
Malaria Journal 2019 18:446, 30 December 2019

Failed diagnoses of some falciparum malaria cases by RDTs are constantly reported in recent years. Plasmodium falciparum histidine-rich protein 2 (pfhpr2) gene deficiency has been found to be the major reason of RDTs failure in many countries. This article analysed the deletion of pfhpr2 gene of falciparum malaria cases isolated in Yunnan Province, China.

Management of imported malaria cases and healthcare institutions in central China, 2012–2017: application of decision tree analysis

December 30, 2019 - 14:10 -- Open Access
Xi-Liang Wang, Jie-Bin Cao, Wei-Dong Zhang, et al.
Malaria Journal 2019 18:429, 18 December 2019

Imported malaria has been an important challenge for China. Fatality rates from malaria increased in China, particularly in Henan Province, primarily due to malpractice and misdiagnoses in healthcare institutions, and the level of imported malaria. This study aims to investigate the relationship between the state of diagnosis and subsequent complications among imported malaria cases at healthcare institutions, based on malaria surveillance data in Henan Province from 2012 to 2017.

Malaria surveillance-response strategies in different transmission zones of the People's Republic of China: preparing for climate change

December 26, 2012 - 16:43 -- Open Access
Yang G, Tanner M, Utzinger J, Malone JB, Bergquist R, Chan EY, Gao Q, Zhou X
Malaria Journal 2012, 11:426 (21 December 2012)

Environmental data obtained from 676 locations across P.R. China, such as monthly temperature and yearly relative humidity (YRH), for the period 1961--2000 were prepared.

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