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anopheline mosquitoes

Not Open Access | Plasmodium falciparum evades immunity of anopheline mosquitoes by interacting with a Pfs47 midgut receptor

February 14, 2020 - 17:06 -- NOT Open Access
Author(s): 
Molina-Cruz A, Canepa GE, Barillas-Mury C, et al.
Reference: 
PNAS February 4, 2020 117 (5) 2597-2605

The surface protein Pfs47 allows Plasmodium falciparum parasites to survive and be transmitted by making them “undetectable” to the mosquito immune system. P. falciparum parasites express Pfs47 haplotypes compatible with their sympatric vectors, while those with incompatible haplotypes are eliminated by the mosquito. We proposed that Pfs47 serves as a “key” that mediates immune evasion by interacting with a mosquito receptor “the lock,” which differs in evolutionarily divergent anopheline mosquitoes. Recombinant Pfs47 (rPfs47) was used to identify the mosquito Pfs47 receptor protein (P47Rec) using far-Western analysis.

Development of an autodissemination strategy for the deployment of novel control agents targeting the common malaria mosquito, Anopheles quadrimaculatus say (Diptera: Culicidae)

April 19, 2018 - 15:32 -- Open Access
Author(s): 
Daniel R. Swale, Zhilin Li, Jake Z. Kraft, Kristen Healy, Mei Liu, Connie M. David, Zhijun Liu, Lane D. Foil
Reference: 
PLoS Negl Trop Dis 12(4): e0006259

Novaluron can be transferred to the adult at a greater efficacy and/or is not degraded as quickly during the gonotropic cycle when compared to pyriproxyfen or triflumuron.

Where have all the mosquito nets gone? Spatial modelling reveals mosquito net distributions across Tanzania do not target optimal Anopheles mosquito habitats

August 24, 2015 - 17:40 -- Open Access
Author(s): 
Emily Acheson, Andrew Plowright, Jeremy Kerr
Reference: 
Malaria Journal 2015, 14:322 (19 August 2015)

Insecticide-treated net ownership is critical for malaria control.

Country: 
Medical Treatment: 

Non-coding RNA gene families in the genomes of anopheline mosquitoes

December 2, 2014 - 16:32 -- Open Access
Author(s): 
Vicky Dritsou, Elena Deligianni, Emmanuel Dialynas, James Allen, Nikos Poulakakis, Christos Louis, Dan Lawson and Pantelis Topalis
Reference: 
BMC Genomics 2014, 15:1038

Our study led to the identification of members of these gene families in the majority of twenty different anopheline taxa. A set of tools for the study of the evolution and molecular biology of important disease vectors has, thus, been obtained.              

Antennal transcriptome profiles of anopheline mosquitoes reveal human host olfactory specialization in Anopheles gambiae

November 5, 2013 - 16:34 -- Open Access
Author(s): 
Rinker DC, Zhou X, Pitts RJ, Rokas A, Zwiebel LJ
Reference: 
BMC Genomics 2013, 14 :749 (1 November 2013)
MalariaWorld

This study improves our understanding of the molecular evolution of chemoreceptors in closely related anophelines and suggests possible mechanisms that underlie the behavioral distinctions in host seeking that, in part, account for the differential vectorial capacity of these mosquitoes.

Protein Kinase C-Dependent Signaling Controls the Midgut Epithelial Barrier to Malaria Parasite Infection in Anopheline Mosquitoes

October 22, 2013 - 07:39 -- Open Access
Author(s): 
Nazzy Pakpour, Lauren Camp, Hannah M. Smithers, Bo Wang, Zhijian Tu, Steven A. Nadler, Shirley Luckhart
Reference: 
PLoS ONE 8(10): e76535
MalariaWorld

Anopheline mosquitoes are the primary vectors of parasites in the genus Plasmodium, the causative agents of malaria.

A dynamic model of some malaria-transmitting anopheline mosquitoes of the Afrotropical region. I. Model description and sensitivity analysis

January 28, 2013 - 15:40 -- Open Access
Author(s): 
Lunde TM, Korecha D, Loha E, Sorteberg A, Lindtjørn B
Reference: 
Malaria Journal 2013, 12:28 (23 January 2013)
MalariaWorld

This study highlights some of the assumptions commonly used when constructing mosquito-malaria models and presents a realistic model of An. gambiae s.s. and An. arabiensis and their interaction.

Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common

December 19, 2012 - 06:25 -- Open Access
Author(s): 
White NJ, Qiao LG, Qi G, Luzzatto L
Reference: 
Malaria Journal 2012, 11:418 (14 December 2012)
MalariaWorld

In areas of low malaria transmission, it is currently recommended that a single dose of primaquine (0.75 mg base/kg; 45 mg adult dose) be added to artemisinin combination treatment (ACT) in acute falciparum malaria to block malaria transmission.

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