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vivax

Spatio-temporal associations between deforestation and malaria incidence in Lao PDR

March 13, 2021 - 16:33 -- Open Access
Author(s): 
Rerolle F, Dantzer E, Lover AA, Marshall JM, Hongvanthong B, Sturrock HJ, Bennett A
Reference: 
Elife. 2021 Mar 9;10:e56974

As countries in the Greater Mekong Sub-region (GMS) increasingly focus their malaria control and elimination efforts on reducing forest-related transmission, greater understanding of the relationship between deforestation and malaria incidence will be essential for programs to assess and meet their 2030 elimination goals. Leveraging village-level health facility surveillance data and forest cover data in a spatio-temporal modeling framework, we found evidence that deforestation is associated with short-term increases, but long-term decreases in confirmed malaria case incidence in Lao People's Democratic Republic (Lao PDR).

Molecular and morphological identification of suspected Plasmodium vivax vectors in Central and Eastern Sudan

March 10, 2021 - 14:49 -- Open Access
Author(s): 
Omnia Fathelrhman Abdelwhab, Arwa Elaagip, Musab M. Albsheer, Ayman Ahmed, Giacomo Maria Paganotti and Muzamil Mahdi Abdel Hamid
Reference: 
Malaria Journal 2021 20:132, 4 March 2021

In spite of the global effort to eliminate malaria, it remains the most significant vector-borne disease of humans. Plasmodium falciparum is the dominant malaria parasite in sub-Saharan Africa. However, Plasmodium vivax is becoming widely spread throughout Africa. The overuse of vector control methods has resulted in a remarkable change in the behaviour of mosquito that feeds on human as well as on vector composition. The aim of this study was to identify Anopheles mosquito species in vivax malaria endemic regions and to investigate their role in P. vivax circumsporozoite protein (Pvcsp) allele diversity.

Plasmodium falciparum outbreak in native communities of Condorcanqui, Amazonas, Perú

February 15, 2021 - 16:14 -- Open Access
Author(s): 
Carla C. Montenegro, T. Pershing Bustamante-Chauca, Cecilia Pajuelo Reyes, Miguel Bernal, Lizandro Gonzales, Rafael Tapia-Limonchi, Juan R. Tejedo and Stella M. Chenet
Reference: 
Malaria Journal 2021 20:88, 12 February 2021

Malaria remains a serious health threat in the Amazonas Region of Peru and approximately 95% of the cases, mainly Plasmodium vivax, are found in native communities of The Rio Santiago District, Condorcanqui Province. In 2019, more than one thousand malaria cases were reported, with an unusual number of Plasmodium falciparum autochthonous cases. The present study aims to report this P. falciparum outbreak while describing the epidemiology of malaria and the risk factors associated in the native communities of Amazonas, Peru.

The top 1%: quantifying the unequal distribution of malaria in Brazil

February 15, 2021 - 16:03 -- Open Access
Author(s): 
Raquel Lana, Narimane Nekkab, Andre M. Siqueira, Cassio Peterka, Paola Marchesini, Marcus Lacerda, Ivo Mueller, Michael White and Daniel Villela
Reference: 
Malaria Journal 2021 20:87, 12 February 2021

As malaria endemic countries strive towards elimination, intensified spatial heterogeneities of local transmission could undermine the effectiveness of traditional intervention policy.

Natural infections with different Plasmodium species induce antibodies reactive to a chimeric Plasmodium vivax recombinant protein

February 15, 2021 - 15:51 -- Open Access
Author(s): 
Jessica N. McCaffery, Balwan Singh, Douglas Nace, Alberto Moreno, Venkatachalam Udhayakumar and Eric Rogier
Reference: 
Malaria Journal 2021 20:86, 12 February 2021

As malaria incidence and transmission in a region decreases, it becomes increasingly difficult to identify areas of active transmission. Improved methods for identifying and monitoring foci of active malaria transmission are needed in areas of low parasite prevalence in order to achieve malaria elimination. Serological assays can provide population-level infection history to inform elimination campaigns.

Transmission-blocking compound candidates against Plasmodium vivax using P. berghei as an initial screening

February 11, 2021 - 09:21 -- Open Access
Author(s): 
Fabbri C, Trindade AO, Andrade FS, Souza MF, Ríos-Velásquez CM, Lacerda MVG, Monteiro WM, Costa FTM, Amino R, Lopes SCP
Reference: 
Mem Inst Oswaldo Cruz. 2021 Feb 8;116:e200513

Different strategies for improvement of malaria control and elimination are based on the blockage of malaria parasite transmission to the mosquito vector. These strategies include the drugs that target the plasmodial sexual stages in humans and the early developmental stages inside mosquitoes.

NOT Open Access | Biomarkers of disease severity in vivax malaria

February 3, 2021 - 15:16 -- NOT Open Access
Author(s): 
Aqeel S, Naheda A, Raza A, Khan W
Reference: 
Parasitol Res. 2021 Feb 3

Severe complications have been observed and established for Plasmodium falciparum as well as P. vivax infections worldwide. Although P. vivax infection is not fully acknowledged as malignant malaria, recently life-threatening complications have been reported to occur in many studies. The recognition of biomarkers with excellent sensitivity and reliability plays a prime role in disease management. Acute inflammatory response and oxidative stress are observed in malaria due to the production of reactive oxygen species.

Anopheles stephensi Mosquitoes as Vectors of Plasmodium vivax and falciparum, Horn of Africa, 2019

February 3, 2021 - 14:04 -- Open Access
Author(s): 
Tadesse FG, Ashine T, Bousema T, et al.
Reference: 
Emerg Infect Dis. 2021 Feb;27(2):603-607

Anopheles stephensi mosquitoes, efficient vectors in parts of Asia and Africa, were found in 75.3% of water sources surveyed and contributed to 80.9% of wild-caught Anopheles mosquitoes in Awash Sebat Kilo, Ethiopia.

The epidemiology and detectability of asymptomatic plasmodium vivax and plasmodium falciparum infections in low, moderate and high transmission settings in Ethiopia

January 27, 2021 - 11:53 -- Open Access
Author(s): 
Elifaged Hailemeskel, Surafel K Tebeje, Fitsum G. Tadesse, et al.
Reference: 
Malaria Journal 2021 20:59, 22 January 2021

As countries move to malaria elimination, detecting and targeting asymptomatic malaria infections might be needed. Here, the epidemiology and detectability of asymptomatic Plasmodium falciparum and Plasmodium vivax infections were investigated in different transmission settings in Ethiopia.

Past eight-year malaria data in Gedeo zone, southern Ethiopia: trend, reporting-quality, spatiotemporal distribution, and association with socio-demographic and meteorological variables

January 27, 2021 - 11:21 -- Open Access
Author(s): 
Molla E, Behaksra SW, Tadesse FG, Dugassa S, Gadisa E, Mamo H
Reference: 
BMC Infect Dis. 2021 Jan 21;21(1):91

Informed decision making is underlined by all tiers in the health system. Poor data record system coupled with under- (over)-reporting of malaria cases affects the country’s malaria elimination activities. Thus, malaria data at health facilities and health offices are important particularly to monitor and evaluate the elimination progresses. This study was intended to assess overall reported malaria cases, reporting quality, spatiotemporal trends and factors associated in Gedeo zone, South Ethiopia.

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