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plasmodium chabaudi

NOT Open Access | Acute Plasmodium chabaudi Infection Dampens Humoral Responses to a Secondary T-Dependent Antigen but Enhances Responses to a Secondary T-Independent Antigen

October 22, 2013 - 07:35 -- NOT Open Access
Author(s): 
Joel R. Wilmore, Alexander C. Maue, Julie S. Lefebvre, Laura Haynes, and Rosemary Rochford
Reference: 
The Journal of Immunology November 1, 2013 vol. 191 no. 9 4731-4739
MalariaWorld

High rates of coinfection occur in malaria endemic regions, leading to more severe disease outcomes.

Quantifying variation in the potential for antibody-mediated apparent competition among nine genotypes of the rodent malaria parasite Plasmodium chabaudi

October 16, 2013 - 18:37 -- Open Access
Author(s): 
Karen J. Fairlie-Clarke, Judith E. Allen, Andrew F. Read, Andrea L. Graham
Reference: 
Infection, Genetics and Evolution, Volume 20, December 2013, Pages 270-275
MalariaWorld

Here, we quantify the potential for antibodies induced by one clone to bind another (i.e., to cause antibody-mediated apparent competition) for nine genetically distinct P. chabaudi clones.

Not Open Access | Acute Plasmodium chabaudi Infection Dampens Humoral Responses to a Secondary T-Dependent Antigen but Enhances Responses to a Secondary T-Independent Antigen

October 2, 2013 - 16:07 -- NOT Open Access
Author(s): 
Joel R. Wilmore, Alexander C. Maue, Julie S. Lefebvre, Laura Haynes, and Rosemary Rochford
Reference: 
The Journal of Immunology September 30, 2013 1301450
MalariaWorld

These data suggest that during P. chabaudi infection, there is a shift toward an extrafollicular Ab response that could be responsible for decreased Ab responses to secondary T-dependent Ags.

The Impact of Genetic Susceptibility to Systemic Lupus Erythematosus on Placental Malaria in Mice

May 22, 2013 - 06:59 -- Open Access
Author(s): 
Michael Waisberg, Christina K. Lin, Chiung-Yu Huang, Mirna Pena, Marlene Orandle, Silvia Bolland, Susan K. Pierce
Reference: 
PLoS ONE 8(5): e62820
MalariaWorld

Severe malaria, including cerebral malaria (CM) and placental malaria (PM), have been recognized to have many of the features of uncontrolled inflammation.

Preconditioning with Hemin Decreases Plasmodium chabaudi adami Parasitemia and Inhibits Erythropoiesis in BALB/c Mice

February 11, 2013 - 18:08 -- Open Access
Author(s): 
Esther Dalko, Véronique Gaudreault, Jaime Sanchez Dardon, Robert Moreau, Tatiana Scorza
Reference: 
PLoS ONE 8(1): e54744
MalariaWorld

Herein, we investigated the impact of heme (hemin) administration on immune parameters and steady state erythropoiesis in BALB/c mice, and on parasitemia and anemia during Plasmodium chabaudi adami infection.

Dried Whole Plant Artemisia annua as an Antimalarial Therapy

January 2, 2013 - 06:35 -- Open Access
Author(s): 
Mostafa A. Elfawal, Melissa J. Towler, Nicholas G. Reich, Douglas Golenbock, Pamela J. Weathers, Stephen M. Rich
Reference: 
PLoS ONE 7(12): e52746
MalariaWorld

Drugs are primary weapons for reducing malaria in human populations.

Mosquito transmission of the rodent malaria parasite Plasmodium chabaudi

December 10, 2012 - 09:01 -- Open Access
Author(s): 
Spence PJ, Jarra W, Lévy P, Nahrendorf W, Langhorne J
Reference: 
Malaria Journal 2012, 11:407 (6 December 2012)
MalariaWorld

This protocol was utilized for mosquito transmission of genetically distinct P. c. chabaudi isolates, highlighting differential parasite virulence within the mosquito vector and the spectrum of host  susceptibility to infection initiated via the natural route, mosquito bite.

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