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rapid diagnostic tests (RDTs)

Comparative performance of four malaria rapid diagnostic tests, Vikia Malaria Pf/Pan, Meriline-Meriscreen Pf/Pv/Pan, Right Sign Malaria Pf/Pan, and Right Sign Malaria Pf, among febrile patients in Gabon

June 26, 2020 - 12:02 -- Open Access
Author(s): 
Ditombi BCM, Minko JI, Tsamba RP, Ngomo JMN, Nymane T, Ognagosso FBB, M'bondoukwe NP, Mawili-Mboumba DP, Akotet MKB
Reference: 
Rev Soc Bras Med Trop. 2020 Jun 22; 53:e20190274

Rapid diagnostic tests (RDTs) are selected based on their performances. Here, we compared the diagnostic performance of different malaria RDTs.

The Importance of an Active Case Detection (ACD) Programme for Malaria among Migrants from Malaria Endemic Countries: The Greek Experience in a Receptive and Vulnerable Area

June 12, 2020 - 14:01 -- Open Access
Author(s): 
Tseroni M, Georgitsou M, Hadjichristodoulou C, et al.
Reference: 
Int J Environ Res Public Health. 2020 Jun 8; 17(11):E4080

Greece has been malaria-free since 1974. In October 2011, following an outbreak of 36 locally acquired malaria (LAM) cases in Evrotas Municipality, a Pro-Active Case Detection (PACD) program for malaria was implemented among migrants from malaria-endemic countries, to support early diagnosis and treatment of cases. We evaluated the PACD program for the years 2012–2017 using indicators such as the number of locally acquired cases, the detection rate/sensitivity and the timeliness of diagnosis and treatment.

Bacteremia in adults with severe malaria

June 8, 2020 - 15:45 -- Open Access
Author(s): 
White NJ
Reference: 
Clin Infect Dis. 2020 Jun 7:ciaa733

Symptomatic malaria is predominantly a disease of childhood in areas of higher transmission (i.e. much of sub-Saharan Africa). Most cases of severe malaria occur in children less than 5 years of age. In these regions both malaria and sepsis are major causes of childhood death, yet the clinical distinction between the two is difficult, particularly if there is no obvious focus of infection. Furthermore, severe malaria predisposes to bacterial infections, particularly with Salmonella sp, so a very sick child  may have both.

Plasmodium falciparum Histidine-Rich Protein 2 and 3 Gene Deletions and Their Implications in Malaria Control

May 25, 2020 - 07:54 -- Open Access
Author(s): 
Nyataya J, Waitumbi J, Mobegi VA, Noreddin A, El Zowalaty ME
Reference: 
Diseases. 2020 May 20; 8(2):E15

Malaria remains the biggest threat to public health, especially among pregnant women and young children in sub-Saharan Africa. Prompt and accurate diagnosis is critical for effective case management and detection of drug resistance. Conventionally, microscopy and rapid diagnostic tests (RDTs) are the tools of choice for malaria diagnosis. RDTs are simple to use and have been extensively used in the diagnosis of malaria among travelers to malaria-endemic regions, routine case management, and surveillance studies.

Malaria case management commodity supply and use by community health workers in Mozambique, 2017

February 26, 2019 - 15:18 -- Open Access
Author(s): 
Elizabeth Davlantes, Cristolde Salomao, Flavio Wate, Deonilde Sarmento, Humberto Rodrigues, Eric S. Halsey, Lauren Lewis, Baltazar Candrinho and Rose Zulliger
Reference: 
Malaria Journal 2019 18:47, 21 February 2019

Variations in geographic and seasonal malaria commodity needs should be considered in CHW kit distribution planning in Mozambique.

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Expanding malaria diagnosis and treatment in Lao PDR: lessons learned from a public–private mix initiative

November 15, 2017 - 16:03 -- Open Access
Author(s): 
Nouannipha Simmalavong, Sengkham Phommixay, Phoudaliphone Kongmanivong, Odai Sichanthongthip, Bouasy Hongvangthong, Deyer Gopinath and David M. Sintasath
Reference: 
Malaria Journal 2017 16:460, 13 November 2017

Ensuring adequate and timely supplies of RDTs and ACT to PPM sites is critical.

The role of early detection and treatment in malaria elimination

July 19, 2016 - 16:20 -- Open Access
Author(s): 
Jordi Landier, Daniel M. Parker, François H. Nosten, et al.
Reference: 
Malaria Journal 2016 15:363, 15 July 2016

Falciparum malaria persists in hard-to-reach areas or demographic groups that are missed by conventional healthcare systems but could be reached by trained community members in a malaria post (MP).

A cross-sectional study of the availability and price of anti-malarial medicines and malaria rapid diagnostic tests in private sector retail drug outlets in rural Western Kenya, 2013

July 19, 2016 - 15:45 -- Open Access
Author(s): 
Urbanus Kioko, Christina Riley, Ann M. Buff, et al.
Reference: 
Malaria Journal 2016 15:359, 12 July 2016

Most outlets never stocked RDTs; therefore, testing prior to treatment was unlikely for customers seeking treatment in the private retail sector.

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HRP2 and pLDH-Based Rapid Diagnostic Tests, Expert Microscopy, and PCR for Detection of Malaria Infection during Pregnancy and at Delivery in Areas of Varied Transmission: A Prospective Cohort Study in Burkina Faso and Uganda

July 19, 2016 - 15:21 -- Open Access
Author(s): 
Daniel J. Kyabayinze, Issaka Zongo, David Bell, et al.
Reference: 
PLoS ONE 11(7): e0156954

The study suggests that HRP2-based RDTs are the most appropriate point-of-care test currently available for use during pregnancy especially for symptomatic women, but will still miss some PCR-positive women.

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A qualitative study of perceptions of a mass test and treat campaign in Southern Zambia and potential barriers to effectiveness

April 24, 2015 - 07:10 -- Open Access
Author(s): 
Kafula Silumbe, Elizabeth Chiyende, Adam Bennett, et al.
Reference: 
Malaria Journal 2015, 14:171 (21 April 2015)

These findings highlight the importance of increased community sensitization as part of mass treatment campaigns for improving campaign coverage and acceptance

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