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plasmodium species

Serological markers to measure recent changes in malaria at population level in Cambodia

November 9, 2016 - 17:13 -- Open Access
Author(s): 
Karen Kerkhof, Vincent Sluydts, Lies Durnez, et al.
Reference: 
Malaria Journal 2016 15:529, 4 November 2016

For Plasmodium falciparum, antibodies against LSA3.RE, GLURP and Pf.GLURP.R2 are most likely to be a reflexion of recent (range from 6 to 8 months) exposure in the Mekong Subregion.

NOT Open Access | Conjugation of N-acylhydrazone and 1,2,4-oxadiazole leads to the identification of active antimalarial agents

November 8, 2016 - 16:56 -- NOT Open Access
Author(s): 
José Maurício dos Santos Filho, Diogo Manoel Alves de Queiroz e Silva, Milena Botelho Pereira Soares, et al.
Reference: 
Bioorganic & Medicinal Chemistry, Volume 24, Issue 22, 15 November 2016, Pages 5693–5701

Malaria, caused by several Plasmodium species, is the major life-threatening parasitic infection worldwide.

Medical Treatment: 

NOT Open Access | Utility of nested polymerase chain reaction over the microscopy and immuno-chromatographic test in the detection of Plasmodium species and their clinical spectrum

August 19, 2016 - 18:41 -- NOT Open Access
Author(s): 
P. Ranjan & U. Ghoshal
Reference: 
Parasitology Research, September 2016, Volume 115, Issue 9, pp 3375–3385

Though demonstration of Plasmodium parasite in peripheral blood on microscopy remains gold standard, it may miss some patients resulting in delay in instituting life-saving therapy.

Seroepidemiology of Plasmodium species infections in Zimbabwean population

May 16, 2016 - 17:19 -- Open Access
Author(s): 
Seth A. Amanfo, Takafira Mduluza, Nicholas Midzi, David R. Cavanagh and Francisca Mutapi
Reference: 
Malaria Journal 2016 15:267, 10 May 2016

There is evidence of a higher exposure to the non-falciparum parasite species than previously reported in Zimbabwe.

Country: 

NOT Open Access | Anti-Self Phosphatidylserine Antibodies Recognize Uninfected Erythrocytes Promoting Malarial Anemia

February 15, 2016 - 18:19 -- NOT Open Access
Author(s): 
Cristina Fernandez-Arias, Juan Rivera-Correa, Ana Rodriguez, et al.
Reference: 
Cell Host & Microbe, Volume 19, Issue 2, 10 February 2016, Pages 194–203

Plasmodium species, the parasitic agents of malaria, invade erythrocytes to reproduce, resulting in erythrocyte loss.

Inhibition by stabilization: targeting the Plasmodium falciparum aldolase–TRAP complex

August 24, 2015 - 17:50 -- Open Access
Author(s): 
Sondra Nemetski, Timothy J Cardozo, Jürgen Bosch, et al.
Reference: 
Malaria Journal 2015, 14:324 (20 August 2015)

This proof-of-concept study presents a novel approach to anti-malarial drug discovery and design.

The influence of host genetics on erythrocytes and malaria infection: is there therapeutic potential?

July 31, 2015 - 15:16 -- Open Access
Author(s): 
Patrick M Lelliott, Brendan J McMorran, Simon J Foote, Gaetan Burgio
Reference: 
Malaria Journal 2015, 14:289 (29 July 2015)

As parasites, Plasmodium species depend upon their host for survival.

Zoonotic malaria – global overview and research and policy needs

September 4, 2014 - 13:29 -- Open Access
Author(s): 
Ranjan Ramasamy
Reference: 
Front. Public Health, 18 August 2014

The four main Plasmodium species that cause human malaria, Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, and Plasmodium ovale, are transmitted between humans by mosquito vectors belonging to the genus Anopheles.

Improving N-terminal protein annotation of Plasmodium species based on signal peptide prediction of orthologous proteins

November 20, 2012 - 06:48 -- Open Access
Author(s): 
Menezes de Neto A, Alvarenga DA, Rezende AM, Resende SS, Souza deRibeiro R, Fontes CJ, Carvalho LH, Alves de Brito CF
Reference: 
Malaria Journal 2012, 11:375 (15 November 2012)
MalariaWorld

The methodological novelty proposed here combining orthology and signal peptide prediction proved to be an effective strategy for the identification of proteins showing wrongly N-terminal annotated sequences, and it might have an important impact in the available data for genome-wide searching of potential vaccine and drug targets and proteins involved in host/parasite interactions, as demonstrated for five Plasmodium species.

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