Gene drive mosquitoes are a novel approach to vector control being developed to help tackle malaria. A gene drive increases the frequency of a desired gene and its phenotypic effect into a mosquito population through reproduction in relatively few generations . Combining gene drive with the precision of gene editing, scientists are able to modify the Anopheles mosquito genome and push modifications through natural vector populations.
Majority of the community members recognized presence of mosquito swarms in their communities but did not associate these swarms with mosquito mating.
Mosquitoes use many cues to assess whether a habitat is conducive for reproduction, possibly including the presence of stimuli from aquatic macrophytes.
This semi-automated qPCR method enables accurate detection of low-level P. falciparum oocyst infections in mosquito midguts, and may improve the sensitivity, specificity and throughput of assays used to evaluate candidate transmission-blocking interventions.
Ivermectin has captured the imagination of a small group of global health scientists as one approach to solving the problem of residual transmission of malaria. This old, so-called wonder drug—an endectocide that targets both endoparasites and ectoparasites—was originally identified as a natural substance by Satoshi Ōmura of Kitasato Institute. The drug was further developed by William Campbell of Merck Labs as a potent anthelmintic, originally for use in veterinary health and targeting more than 20 species of helminth.
Fine-scale differences in endophagy and exophagy, and temporal differences among months and hours exist in biting patterns among mosquito taxa in southern coastal Ecuador.
The proposed bead-beating CSP-ELISA/qPCR methodology considerably increases throughput for the detection of mosquito infection.
The new design houses had fewer mosquitoes and were cooler than modified and unmodified traditional homes.
The current study demonstrates that concentration methods of P. falciparum gametocyte-infected whole blood samples can enhance transmission in mosquito-feeding assays.
Malaria-related mortality has slowly decreased over the past decade; however, eradication of malaria requires the development of new antimalarial chemotherapies that target liver stages of the parasite and combat the emergence of drug resistance.