Plasmodium salivary sporozoites are the infectious form of the malaria parasite and are dormant inside salivary glands of Anopheles mosquitoes.
The device was capable of carrying out the RPA reaction and detecting meaningful amounts of synthetic Plasmodium DNA in a self-sealing and self-contained device.
Glycoconjugates are important mediators of host-pathogen interactions and are usually very abundant in the surface of many protozoan parasites.
Gene fusion is a common mechanism of protein evolution that has mainly been discussed in the context of multidomain or symmetric proteins.
Inhibition of nitric oxide (NO) signaling may contribute to pathological activation of the vascular endothelium during severe malaria infection.
Parasitic helminths establish chronic infections in mammalian hosts. Helminth/Plasmodium co-infections occur frequently in endemic areas.
Plasmodium parasites must complete development in the mosquito vector for transmission to occur.
Stage-specific transcription is a fundamental biological process in the life cycle of the Plasmodium parasite.
Here we describe a SYBR Green-based real-time PCR assay for Plasmodium species identification from whole blood, which uses a panel of reactions to detect species-specific non-18S rRNA gene targets.
We found that the Plasmodium genome encodes two genuine HMGB factors, Plasmodium HMGB1 and HMGB2 that encompass, as their human counterparts, a pro-inflammatory domain.