Innate immunity is an ancient and conserved defense system that provides an early effective response against invaders.
The putative Plasmodium translocon of exported proteins (PTEX) is essential for transport of malarial effector proteins across a parasite-encasing vacuolar membrane into host erythrocytes, but the mechanism of this process remains unknown.
Currently, there are very few studies of avian malaria that investigate relationships among the host-vector-parasite triad concomitantly.
Cell motility is essential for protozoan and metazoan organisms and typically relies on the dynamic turnover of actin filaments.
Currently, the most effective antimalarial is artemisinin, which is extracted from the leaves of medicinal herb Artemisia annua L. (A. annua).
Although Wolbachia-infected mosquitoes fare overall better than uninfected ones, Wolbachia does not confer a sufficiently high reproductive boost to mosquitoes to compensate for the reproductive losses inflicted by Plasmodium.
In this article, we first review the history of malarial infection in Korea by means of studies on Joseon documents and the related scientific data on the evolutionary history of P. vivax in Asia.
Multiplicity of infection (MOI), also termed complexity of infection (COI), is defined as the number of genetically distinct parasite strains co-infecting a single host, which is an important indicator of malaria epidemiology.
Ever since Plasmodium intraerythrocytic development was reported to proceed via an unusual “hardwired” transcriptional cascade, the control of gene transcription in malaria parasites has been an area of intense investigation.
Malaria parasites (Plasmodium) can change the attractiveness of their vertebrate hosts to Anopheles vectors, leading to a greater number of vector–host contacts and increased transmission.